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Related papers: Causal Discovery under Off-Target Interventions

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Causal inference methods are widely applied in various decision-making domains such as precision medicine, optimal policy and economics. Central to these applications is the treatment effect estimation of intervention strategies. Current…

Artificial Intelligence · Computer Science 2021-05-28 Tri Dung Duong , Qian Li , Guandong Xu

A major challenge in causal discovery from observational data is the absence of perfect interventions, making it difficult to distinguish causal features from spurious ones. We propose an innovative approach, Feature Matching Intervention…

Machine Learning · Statistics 2025-03-06 Haoze Li , Jun Xie

The causal revolution has stimulated interest in understanding complex relationships in various fields. Most of the existing methods aim to discover causal relationships among all variables within a complex large-scale graph. However, in…

Machine Learning · Computer Science 2023-11-02 Hengrui Cai , Yixin Wang , Michael Jordan , Rui Song

Uncovering the underlying causal mechanisms of complex real-world systems remains a significant challenge, as these systems often entail high data collection costs and involve unknown interventions. We introduce MetaCaDI, the first…

Machine Learning · Statistics 2025-10-28 Hans Jarett Ong , Yoichi Chikahara , Tomoharu Iwata

Probabilistic Graphical Bayesian models of causation have continued to impact on strategic analyses designed to help evaluate the efficacy of different interventions on systems. However, the standard causal algebras upon which these…

Healthcare artificial intelligence systems often degrade in performance when deployed across institutions, with documented performance drops and perpetuation of discriminatory patterns embedded in data. This brittleness comes, in part, from…

Machine Learning · Computer Science 2026-03-30 Munib Mesinovic , Max Buhlan , Tingting Zhu

Sequential experimental design to discover interventions that achieve a desired outcome is a key problem in various domains including science, engineering and public policy. When the space of possible interventions is large, making an…

Machine Learning · Computer Science 2023-08-17 Jiaqi Zhang , Louis Cammarata , Chandler Squires , Themistoklis P. Sapsis , Caroline Uhler

Directed acyclic graphical (DAG) models are a powerful tool for representing causal relationships among jointly distributed random variables, especially concerning data from across different experimental settings. However, it is not always…

Machine Learning · Statistics 2026-04-03 Francisco Madaleno , Pratik Misra , Alex Markham

Incorporating causal knowledge and mechanisms is essential for refining causal models and improving downstream tasks such as designing new treatments. In this paper, we introduce a novel concept in causal discovery, termed interventional…

Machine Learning · Computer Science 2025-10-31 Zhigao Guo , Feng Dong

Causal discovery from i.i.d. observational data is known to be generally ill-posed. We demonstrate that if we have access to the distribution {induced} by a structural causal model, and additional data from (in the best case) \textit{only…

Machine Learning · Statistics 2026-05-15 Francesco Montagna

Fair machine learning aims to prevent discrimination against individuals or sub-populations based on sensitive attributes such as gender and race. In recent years, causal inference methods have been increasingly used in fair machine…

Machine Learning · Computer Science 2024-03-11 Aoqi Zuo , Yiqing Li , Susan Wei , Mingming Gong

Causal discovery from time-series data aims to capture both intra-slice (contemporaneous) and inter-slice (time-lagged) causality between variables within the temporal chain, which is crucial for various scientific disciplines. Compared to…

Machine Learning · Computer Science 2026-01-26 Rujia Shen , Boran Wang , Chao Zhao , Yi Guan , Jingchi Jiang

Causality plays a pivotal role in various fields of study. Based on the framework of causal graphical models, previous works have proposed identifying whether a variable is a cause or non-cause of a target in every Markov equivalent graph…

Machine Learning · Statistics 2024-08-16 Qingyuan Zheng , Yue Liu , Yangbo He

The task of inferring high-level causal variables from low-level observations, commonly referred to as causal representation learning, is fundamentally underconstrained. As such, recent works to address this problem focus on various…

Machine Learning · Statistics 2024-03-26 Simon Bing , Urmi Ninad , Jonas Wahl , Jakob Runge

We present a generalized linear structural causal model, coupled with a novel data-adaptive linear regularization, to recover causal directed acyclic graphs (DAGs) from time series. By leveraging a recently developed stochastic monotone…

Machine Learning · Computer Science 2023-01-31 Song Wei , Yao Xie , Christopher S. Josef , Rishikesan Kamaleswaran

We present a generalized linear structural causal model, coupled with a novel data-adaptive linear regularization, to recover causal directed acyclic graphs (DAGs) from time series. By leveraging a recently developed stochastic monotone…

Machine Learning · Computer Science 2023-09-27 Song Wei , Yao Xie , Christopher S. Josef , Rishikesan Kamaleswaran

Neural networks have proven to be effective at solving machine learning tasks but it is unclear whether they learn any relevant causal relationships, while their black-box nature makes it difficult for modellers to understand and debug…

Machine Learning · Computer Science 2023-08-02 Fabrizio Russo , Francesca Toni

Biomarker discovery from high-throughput transcriptomic data is crucial for advancing precision medicine. However, existing methods often neglect gene-gene regulatory relationships and lack stability across datasets, leading to conflation…

Quantitative Methods · Quantitative Biology 2025-11-18 Chaowang Lan , Jingxin Wu , Yulong Yuan , Chuxun Liu , Huangyi Kang , Caihua Liu

To draw scientifically meaningful conclusions and build reliable models of quantitative phenomena, cause and effect must be taken into consideration (either implicitly or explicitly). This is particularly challenging when the measurements…

Machine Learning · Computer Science 2020-12-11 Max A. Little , Reham Badawy

Causal discovery aims to extract qualitative causal knowledge in the form of causal graphs from data. Because causal ground truth is rarely known in the real world, simulated data plays a vital role in evaluating the performance of the…

Machine Learning · Computer Science 2025-12-17 Rebecca J. Herman , Jonas Wahl , Urmi Ninad , Jakob Runge
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