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Accurate molecular force fields are of paramount importance for the efficient implementation of molecular dynamics techniques at large scales. In the last decade, machine learning methods have demonstrated impressive performances in…

Quantum Physics · Physics 2022-07-22 Oriel Kiss , Francesco Tacchino , Sofia Vallecorsa , Ivano Tavernelli

Genetic algorithms are highly effective optimization techniques for many computationally challenging problems, including combinatorial optimization tasks like portfolio optimization. Quantum computing has also shown potential in addressing…

Emerging Technologies · Computer Science 2025-04-28 Mohammad Kashfi Haghighi , Matthieu Fortin-Deschênes , Christophe Pere , Mickaël Camus

Quantum computers offer the potential for efficiently sampling from complex probability distributions, attracting increasing interest in generative modeling within quantum machine learning. This surge in interest has driven the development…

Quantum Physics · Physics 2025-11-19 Maria Demidik , Cenk Tüysüz , Nico Piatkowski , Michele Grossi , Karl Jansen

Effective and accurate diagnosis of diseases such as cancer, diabetes, and heart failure is crucial for timely medical intervention and improving patient survival rates. Machine learning has revolutionized diagnostic methods in recent years…

Machine Learning · Computer Science 2025-12-02 Antonio Tudisco , Deborah Volpe , Giovanna Turvani

The novel nature of SARS-CoV-2 calls for the development of efficient de novo drug design approaches. In this study, we propose an end-to-end framework, named CogMol (Controlled Generation of Molecules), for designing new drug-like small…

Computational methods are the most effective tools we have besides scientific experiments to explore the properties of complex biological systems. Progress is slowing because digital silicon computers have reached their limits in terms of…

Quantum Physics · Physics 2020-04-03 Viv Kendon

Wideband and low-latency requirements in sixth-generation (6G) networks demand detectors that approach maximum-likelihood (ML) performance without incurring exponential complexity. This work develops a hybrid quantum-classical detection…

Networking and Internet Architecture · Computer Science 2025-11-07 Maryam Tariq , Omar Alhussein , Raneem Abdelraheem , Abdullah Quran , Georges Kaddoum , Sami Muhaidat

Dose-response prediction in cancer is an active application field in machine learning. Using large libraries of \textit{in-vitro} drug sensitivity screens, the goal is to develop accurate predictive models that can be used to guide…

Quantitative Methods · Quantitative Biology 2024-07-02 Leiv Rønneberg , Vidhi Lalchand , Paul D. W. Kirk

The rapid expansion of biomolecular datasets presents significant challenges for computational biology. Quantum computing emerges as a promising solution to address these complexities. This study introduces a novel quantum framework for…

Chemical Physics · Physics 2025-07-02 Don Roosan , Rubayat Khan , Saif Nirzhor , Tiffany Khou , Fahmida Hai

We develop a general method for incentive-based programming of hybrid quantum-classical computing systems using reinforcement learning, and apply this to solve combinatorial optimization problems on both simulated and real gate-based…

Quantum Physics · Physics 2019-08-23 Keri A. McKiernan , Erik Davis , M. Sohaib Alam , Chad Rigetti

High-energy materials (HEMs) are critical for propulsion and defense domains, yet their discovery remains constrained by experimental data and restricted access to testing facilities. This work presents a novel approach toward high-energy…

Machine Learning · Computer Science 2025-10-31 Siddharth Verma , Alankar Alankar

Magnetic molecules, modelled as finite-size spin systems, are test-beds for quantum phenomena and could constitute key elements in future spintronics devices, long-lasting nanoscale memories or noise-resilient quantum computing platforms.…

Quantum Physics · Physics 2021-03-16 A. Chiesa , F. Tacchino , M. Grossi , P. Santini , I. Tavernelli , D. Gerace , S. Carretta

The design of coordination compounds with target properties often requires years of continuous feedback loop between theory, simulations and experiments. In the case of magnetic molecules, this conventional strategy has indeed led to the…

Materials Science · Physics 2025-04-21 Lion Frangoulis , Zahra Khatibi , Lorenzo A. Mariano , Alessandro Lunghi

Quantum computing has gained a lot of attention recently, and scientists have seen potential applications in this field using quantum computing for Cryptography and Communication to Machine Learning and Healthcare. Protein folding has been…

Quantum Physics · Physics 2022-11-16 Hasan Mustafa , Sai Nandan Morapakula , Prateek Jain , Srinjoy Ganguly

Quantum computing has been on the rise in recent years, evidenced by a surge in publications on quantum software engineering and testing. Progress in quantum hardware has also been notable, with the introduction of impressive systems like…

Software Engineering · Computer Science 2024-10-03 Sinhué García Gil , Luis Llana Díaz , José Ignacio Requeno Jarabo

Drug discovery is vitally important for protecting human against disease. Target-based screening is one of the most popular methods to develop new drugs in the past several decades. This method efficiently screens candidate drugs inhibiting…

Quantitative Methods · Quantitative Biology 2022-11-22 Fan Hu , Dongqi Wang , Huazhen Huang , Yishen Hu , Peng Yin

Recent advancements in generative models have established state-of-the-art benchmarks in the generation of molecules and novel drug candidates. Despite these successes, a significant gap persists between generative models and the…

Machine Learning · Computer Science 2024-10-10 Aditya Malusare , Vaneet Aggarwal

Solving problems related to planning and operations of large-scale power systems is challenging on classical computers due to their inherent nature as mixed-integer and nonlinear problems. Quantum computing provides new avenues to approach…

Quantum Physics · Physics 2025-05-02 Willie Aboumrad , Phani R V Marthi , Suman Debnath , Martin Roetteler , Evgeny Epifanovsky

Control theory has seen recently impactful applications in network science, especially in connections with applications in network medicine. A key topic of research is that of finding minimal external interventions that offer control over…

Molecular Networks · Quantitative Biology 2020-07-10 Victor-Bogdan Popescu , Krishna Kanhaiya , Iulian Năstac , Eugen Czeizler , Ion Petre