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Background: Recent advancements in large language models (LLMs) offer potential benefits in healthcare, particularly in processing extensive patient records. However, existing benchmarks do not fully assess LLMs' capability in handling…

Large Language Models (LLMs) are increasingly being integrated into various medical fields, including mental health support systems. However, there is a gap in research regarding the effectiveness of LLMs in non-English mental health…

Computation and Language · Computer Science 2026-02-10 Konstantinos Skianis , John Pavlopoulos , A. Seza Doğruöz

Large language models (LLMs) have shown impressive potential in helping with numerous medical challenges. Deploying LLMs in high-stakes applications such as medicine, however, brings in many concerns. One major area of concern relates to…

Computation and Language · Computer Science 2025-04-15 Hamed Fayyaz , Raphael Poulain , Rahmatollah Beheshti

Large language models (LLMs) have shown potential in biomedical applications, leading to efforts to fine-tune them on domain-specific data. However, the effectiveness of this approach remains unclear. This study evaluates the performance of…

While large language models (LLMs) play increasingly significant roles in society, research shows they continue to generate content that reflects social bias against sensitive groups. Existing benchmarks effectively identify these biases,…

Computation and Language · Computer Science 2026-03-12 Tian Xie , Tongxin Yin , Vaishakh Keshava , Xueru Zhang , Siddhartha Reddy Jonnalagadda

Cognitive biases often shape human decisions. While large language models (LLMs) have been shown to reproduce well-known biases, a more critical question is whether LLMs can predict biases at the individual level and emulate the dynamics of…

Artificial Intelligence · Computer Science 2026-02-27 Stephen Pilli , Vivek Nallur

We present a benchmark for assessing the capability of Large Language Models (LLMs) to discern intercardinal directions between geographic locations and apply it to three prominent LLMs: GPT-3.5, GPT-4, and Llama-2. This benchmark…

Computation and Language · Computer Science 2024-06-05 Nir Fulman , Abdulkadir Memduhoğlu , Alexander Zipf

As language models (LMs) become integral to fields like healthcare, law, and journalism, their ability to differentiate between fact, belief, and knowledge is essential for reliable decision-making. Failure to grasp these distinctions can…

Computation and Language · Computer Science 2024-10-29 Mirac Suzgun , Tayfun Gur , Federico Bianchi , Daniel E. Ho , Thomas Icard , Dan Jurafsky , James Zou

The potential to provide patients with faster information access while allowing medical specialists to concentrate on critical tasks makes medical domain dialog agents appealing. However, the integration of large-language models (LLMs) into…

Computation and Language · Computer Science 2023-08-30 Fabian Lechner , Allison Lahnala , Charles Welch , Lucie Flek

Large language models (LLMs) are emerging as valuable tools to support clinicians in routine decision-making. HIV management is a compelling use case due to its complexity, including diverse treatment options, comorbidities, and adherence…

Computation and Language · Computer Science 2025-07-28 Gonzalo Cardenal-Antolin , Jacques Fellay , Bashkim Jaha , Roger Kouyos , Niko Beerenwinkel , Diane Duroux

Objective: Large language models (LLMs) are increasingly applied in biomedical settings, and existing benchmark datasets have played an important role in supporting model development and evaluation. However, these benchmarks often have…

Computation and Language · Computer Science 2026-01-21 Kriti Bhattarai , Vipina K. Keloth , Donald Wright , Andrew Loza , Yang Ren , Hua Xu

Large language models (LLMs) have made rapid improvement on medical benchmarks, but their unreliability remains a persistent challenge for safe real-world uses. To design for the use LLMs as a category, rather than for specific models,…

Computation and Language · Computer Science 2024-10-14 Andrew M. Bean , Karolina Korgul , Felix Krones , Robert McCraith , Adam Mahdi

Large Language Models (LLMs) have achieved high accuracy on medical question-answer (QA) benchmarks, yet their capacity for flexible clinical reasoning has been debated. Here, we asked whether advances in reasoning LLMs improve their…

Computation and Language · Computer Science 2026-01-21 Kie Shidara , Preethi Prem , Jonathan Kim , Anna Podlasek , Feng Liu , Ahmed Alaa , Danilo Bernardo

Assessments of algorithmic bias in large language models (LLMs) are generally catered to uncovering systemic discrimination based on protected characteristics such as sex and ethnicity. However, there are over 180 documented cognitive…

Human-Computer Interaction · Computer Science 2023-08-30 Alaina N. Talboy , Elizabeth Fuller

Large Language Models (LLMs) are expected to significantly contribute to patient care, diagnostics, and administrative processes. Emerging biomedical LLMs aim to address healthcare-specific challenges, including privacy demands and…

Computation and Language · Computer Science 2025-10-14 Amin Dada , Marie Bauer , Amanda Butler Contreras , Osman Alperen Koraş , Constantin Marc Seibold , Kaleb E Smith , Jens Kleesiek

Despite high performance on clinical benchmarks, large language models may reach correct conclusions through faulty reasoning, a failure mode with safety implications for oncology decision support that is not captured by accuracy-based…

$\textbf{Objectives}$: Large Language Models (LLMs) such as ChatGPT and Med-PaLM have excelled in various medical question-answering tasks. However, these English-centric models encounter challenges in non-English clinical settings,…

Computation and Language · Computer Science 2024-01-31 Jiageng Wu , Xian Wu , Zhaopeng Qiu , Minghui Li , Yingying Zhang , Yefeng Zheng , Changzheng Yuan , Jie Yang

The integration of large language models (LLMs) into healthcare holds promise to enhance clinical decision-making, yet their susceptibility to biases remains a critical concern. Gender has long influenced physician behaviors and patient…

As Large Language Models (LLMs) are increasingly integrated into healthcare to address complex inquiries, ensuring their reliability remains a critical challenge. Recent studies have highlighted that generic LLMs often struggle in clinical…

Computation and Language · Computer Science 2026-04-01 Bian Sun , Zhenjian Wang , Orvill de la Torre , Zirui Wang

Recent advancements in large language models (LLMs) have transformed the field of question answering (QA). However, evaluating LLMs in the medical field is challenging due to the lack of standardized and comprehensive datasets. To address…

Computation and Language · Computer Science 2023-10-24 Junling Liu , Peilin Zhou , Yining Hua , Dading Chong , Zhongyu Tian , Andrew Liu , Helin Wang , Chenyu You , Zhenhua Guo , Lei Zhu , Michael Lingzhi Li