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Background: Conventional cardiovascular magnetic resonance (CMR) in paediatric and congenital heart disease uses 2D, breath-hold, balanced steady state free precession (bSSFP) cine imaging for assessment of function and cardiac-gated,…
Alterations in the geometry and function of the heart define well-established causes of cardiovascular disease. However, current approaches to the diagnosis of cardiovascular diseases often rely on subjective human assessment as well as…
In this paper, we propose an enhanced 3D myocardial strain estimation procedure, which combines complementary displacement information from multiple orientations of a single imaging modality (untagged CMR SSFP images). To estimate…
Large prospective epidemiological studies acquire cardiovascular magnetic resonance (CMR) images for pre-symptomatic populations and follow these over time. To support this approach, fully automatic large-scale 3D analysis is essential. In…
Electrocardiograms (ECGs) are commonly used by cardiologists to detect heart-related pathological conditions. Reliable collections of ECGs are crucial for precise diagnosis. However, in clinical practice, the assignment of captured ECG…
Delineation of the cardiac structures from 2D echocardiographic images is a common clinical task to establish a diagnosis. Over the past decades, the automation of this task has been the subject of intense research. In this paper, we…
Twelve-lead electrocardiography (ECG) is essential for cardiovascular diagnosis, but its long-term acquisition in daily life is constrained by complex and costly hardware. Recent efforts have explored reconstructing ECG from low-cost…
Accurate three-dimensional (3D) reconstruction of cardiac chamber motion from time-resolved medical imaging modalities is of growing interest in both the clinical and biomechanical fields. Despite recent advancement, the cardiac motion…
In this work we apply reduced basis methods for parametric PDEs to an isogeometric formulation based on NURBS. The motivation for this work is an integrated and complete work pipeline from CAD to parametrization of domain geometry, then…
Quantitative assessment of cardiac left ventricle (LV) morphology is essential to assess cardiac function and improve the diagnosis of different cardiovascular diseases. In current clinical practice, LV quantification depends on the…
The traditional interpretation of Intravascular Ultrasound (IVUS) images during Percutaneous Coronary Intervention (PCI) is time-intensive and inconsistent, relying heavily on physician expertise. Regulatory restrictions and privacy…
In this contribution, we provide a new mass lumping scheme for explicit dynamics in isogeometric analysis (IGA). To this end, an element formulation based on the idea of dual functionals is developed. Non-Uniform Rational B-splines (NURBS)…
Combining physics-based modeling with data-driven methods is critical to enabling the translation of computational methods to clinical use in cardiology. The use of rigorous differential equations combined with machine learning tools allows…
Accurate geometric quantification of the human heart is a key step in the diagnosis of numerous cardiac diseases, and in the management of cardiac patients. Ultrasound imaging is the primary modality for cardiac imaging, however acquisition…
Computer-based simulations of non-invasive cardiac electrical outputs, such as electrocardiograms and body surface potential maps, usually entail severe computational costs due to the need of capturing fine-scale processes and to the…
Accurate segmentation of the heart is an important step towards evaluating cardiac function. In this paper, we present a fully automated framework for segmentation of the left (LV) and right (RV) ventricular cavities and the myocardium…
This study presents a novel methodology for stratifying post-myocardial infarction patients at risk of ventricular arrhythmias using patient-specific 3D cardiac models derived from late gadolinium enhancement cardiovascular magnetic…
Echocardiography has become an indispensable clinical imaging modality for general heart health assessment. From calculating biomarkers such as ejection fraction to the probability of a patient's heart failure, accurate segmentation of the…
Computational fluid dynamics (CFD) can be used for evaluation of hemodynamics. However, its routine use is limited by labor-intensive manual segmentation, CFD mesh creation, and time-consuming simulation. This study aims to train a deep…
Cardiovascular waveforms contain information for clinical diagnosis. By "learning" and organizing the subtle change of waveform morphology from large amounts of raw waveform data, unsupervised manifold learning helps delineate a…