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Unlike Right Atrium (RA), Left Atrium (LA) presents distinctive challenges, including much thinner myocardial walls, complex and irregular morphology, as well as diversity in individual's structure, making off-the-shelf methods designed for…

Image and Video Processing · Electrical Eng. & Systems 2024-05-29 Abdul Qayyum , Moona Mazher , Angela Lee , Jose A Solis-Lemus , Imran Razzak , Steven A Niederer

We propose an end-to-end deep neural network (DNN) which can simultaneously segment the left atrial (LA) cavity and quantify LA scars. The framework incorporates the continuous spatial information of the target by introducing a spatially…

Image and Video Processing · Electrical Eng. & Systems 2020-06-24 Lei Li , Xin Weng , Julia A. Schnabel , Xiahai Zhuang

The functional analysis of the left atrium (LA) is important for evaluating cardiac health and understanding diseases like atrial fibrillation. Cine MRI is ideally placed for the detailed 3D characterization of LA motion and deformation but…

Computer Vision and Pattern Recognition · Computer Science 2024-09-19 Christoforos Galazis , Samuel Shepperd , Emma Brouwer , Sandro Queirós , Ebraham Alskaf , Mustafa Anjari , Amedeo Chiribiri , Jack Lee , Anil A. Bharath , Marta Varela

Visualizing disease-induced scarring and fibrosis in the heart on cardiac magnetic resonance (CMR) imaging with contrast enhancement (LGE) is paramount in characterizing disease progression and quantifying pathophysiological substrates of…

Image and Video Processing · Electrical Eng. & Systems 2021-01-12 Haley G. Abramson , Dan M. Popescu , Rebecca Yu , Changxin Lai , Julie K. Shade , Katherine C. Wu , Mauro Maggioni , Natalia A. Trayanova

Atrial fibrillation (AF) is the most common arrhythmia, increasing the risk of stroke, heart failure, and other cardiovascular complications. While AF detection algorithms perform well in identifying persistent AF, early-stage progression,…

Machine Learning · Computer Science 2025-08-28 Yongbin Lee , Ki H. Chon

Atrial fibrillation (AF) is the most common type of cardiac arrhythmia. It is associated with an increased risk of stroke, heart failure, and other cardiovascular complications, but can be clinically silent. Passive AF monitoring with…

Machine Learning · Computer Science 2024-03-12 Zhicheng Guo , Cheng Ding , Duc H. Do , Amit Shah , Randall J. Lee , Xiao Hu , Cynthia Rudin

Left atrial appendage (LAA) closure (LAAC) is a minimally invasive implant-based method to prevent cardiovascular stroke in patients with non-valvular atrial fibrillation. Assessing the LAA orifice in preoperative CT angiography plays a…

Computer Vision and Pattern Recognition · Computer Science 2020-12-21 Walid Abdullah Al , Il Dong Yun , Eun Ju Chun

Nowadays, cardiac diagnosis largely depends on left ventricular function assessment. With the help of the segmentation deep learning model, the assessment of the left ventricle becomes more accessible and accurate. However, deep learning…

Computer Vision and Pattern Recognition · Computer Science 2021-10-29 Hang Duong Thi Thuy , Tuan Nguyen Minh , Phi Nguyen Van , Long Tran Quoc

More than 13 million people suffer from ischemic cerebral stroke worldwide each year. Thrombolytic treatment can reduce brain damage but has a narrow treatment window. Computed Tomography Perfusion imaging is a commonly used primary…

Image and Video Processing · Electrical Eng. & Systems 2021-04-22 Luca Tomasetti , Kjersti Engan , Mahdieh Khanmohammadi , Kathinka Dæhli Kurz

We develop a deep learning model, ABioSPATH, to predict the one-year risk of ischemic stroke (IS) in atrial fibrillation (AF) patients. The model integrates drug-protein-disease pathways and real-world clinical data of AF patients to…

Quantitative Methods · Quantitative Biology 2024-08-27 Zhiheng Lyu , Jiannan Yang , Zhongzhi Xu , Weilan Wang , Weibin Cheng , Kwok-Leung Tsui , Gary Tse , Qingpeng Zhang

Late gadolinium enhancement magnetic resonance imaging (LGE MRI) appears to be a promising alternative for scar assessment in patients with atrial fibrillation (AF). Automating the quantification and analysis of atrial scars can be…

Computer Vision and Pattern Recognition · Computer Science 2019-02-22 Lei Li , Fuping Wu , Guang Yang , Lingchao Xu , Tom Wong , Raad Mohiaddin , David Firmin , Jennifer Keegan , Xiahai Zhuang

In this work, we propose to resolve the issue existing in current deep learning based organ segmentation systems that they often produce results that do not capture the overall shape of the target organ and often lack smoothness. Since…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yuan Xue , Hui Tang , Zhi Qiao , Guanzhong Gong , Yong Yin , Zhen Qian , Chao Huang , Wei Fan , Xiaolei Huang

Two-dimensional representation of 3D anatomical structures is a simple and intuitive way for analysing patient information across populations and image modalities. It also allows convenient visualizations that can be included in clinical…

Accurate segmentation and localization of left atrial (LA) ablation scars from Late gadolinium enhancement (LGE)-MRI is essential for assessing the lesion completeness and guiding ablation therapy. Incomplete or discontinuous lesions can…

Image and Video Processing · Electrical Eng. & Systems 2026-05-01 Bipasha Kundu , Cristian Linte

Segmentation of the left atrium (LA) is crucial for assessing its anatomy in both pre-operative atrial fibrillation (AF) ablation planning and post-operative follow-up studies. In this paper, we present a fully automated framework for left…

Computer Vision and Pattern Recognition · Computer Science 2019-02-28 Chen Chen , Wenjia Bai , Daniel Rueckert

Pre-operative Abdominal Aortic Aneurysm (AAA) 3D shape is critical for customized stent-graft design in Fenestrated Endovascular Aortic Repair (FEVAR). Traditional segmentation approaches implement expert-designed feature extractors while…

Computer Vision and Pattern Recognition · Computer Science 2018-04-10 Jian-Qing Zheng , Xiao-Yun Zhou , Qing-Biao Li , Celia Riga , Guang-Zhong Yang

Cardiac MR image segmentation is essential for the morphological and functional analysis of the heart. Inspired by how experienced clinicians assess the cardiac morphology and function across multiple standard views (i.e. long- and…

Image and Video Processing · Electrical Eng. & Systems 2019-12-18 Chen Chen , Carlo Biffi , Giacomo Tarroni , Steffen Petersen , Wenjia Bai , Daniel Rueckert

Computed Tomography (CT) is commonly used to image acute ischemic stroke (AIS) patients, but its interpretation by radiologists is time-consuming and subject to inter-observer variability. Deep learning (DL) techniques can provide automated…

Image and Video Processing · Electrical Eng. & Systems 2023-10-02 Alessandro Fontanella , Wenwen Li , Grant Mair , Antreas Antoniou , Eleanor Platt , Paul Armitage , Emanuele Trucco , Joanna Wardlaw , Amos Storkey

Semantic segmentation using convolutional neural networks (CNNs) is the state-of-the-art for many medical segmentation tasks including left ventricle (LV) segmentation in cardiac MR images. However, a drawback is that these CNNs lack…

Image and Video Processing · Electrical Eng. & Systems 2022-08-18 Sofie Tilborghs , Tom Dresselaers , Piet Claus , Jan Bogaert , Frederik Maes

Medical image segmentation is often considered as the task of labelling each pixel or voxel as being inside or outside a given anatomy. Processing the images at their original size and resolution often result in insuperable memory…

Image and Video Processing · Electrical Eng. & Systems 2025-04-28 Kristine Sørensen , Oscar Camara , Ole de Backer , Klaus Kofoed , Rasmus Paulsen