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Related papers: Large-Language-Model Empowered Dose Volume Histogr…

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Dose volume histograms are a useful tool in state-of-the-art radiotherapy planning, and it is essential to be aware of their limitations. Dose distributions computed by treatment planning systems are affected by several sources of…

Medical Physics · Physics 2007-06-13 Francisco Cutanda-Henriquez , Silvia Vargas-Castrillon

Radiotherapy (RT) is a critical cancer treatment, with volumetric modulated arc therapy (VMAT) being a commonly used technique that enhances dose conformity by dynamically adjusting multileaf collimator (MLC) positions and monitor units…

Medical Physics · Physics 2025-06-26 Stefanos Achlatis , Efstratios Gavves , Jan-Jakob Sonke

Radiotherapy (RT) patient scheduling is a complex operational problem. Current scheduling often relies on manual coordination and can be difficult to adapt to changing clinical demands. This study evaluated the feasibility of using a large…

Conventional planning objectives in optimization of intensity-modulated radiotherapy treatment (IMRT) plans are designed to minimize the violation of dose-volume histogram (DVH) thresholds using penalty functions. Although successful in…

Medical Physics · Physics 2023-07-19 Lovisa Engberg , Kjell Eriksson , Anders Forsgren , Björn Hårdemark

Radiotherapy is sensitive to executional and preparational uncertainties that propagate to uncertainty in dose and plan quality indicators like dose-volume histograms (DVHs). Current approaches to quantify and mitigate such uncertainties…

Medical Physics · Physics 2020-10-27 Niklas Wahl , Philipp Hennig , Hans-Peter Wieser , Mark Bangert

Target volume contouring for radiation therapy is considered significantly more challenging than the normal organ segmentation tasks as it necessitates the utilization of both image and text-based clinical information. Inspired by the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Yujin Oh , Sangjoon Park , Hwa Kyung Byun , Yeona Cho , Ik Jae Lee , Jin Sung Kim , Jong Chul Ye

High-dose-rate (HDR) brachytherapy plays a critical role in the treatment of locally advanced cervical cancer but remains highly dependent on manual treatment planning expertise. The objective of this study is to develop a fully automated…

The global demand for radiologists is increasing rapidly due to a growing reliance on medical imaging services, while the supply of radiologists is not keeping pace. Advances in computer vision and image processing technologies present…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Shehroz S. Khan , Petar Przulj , Ahmed Ashraf , Ali Abedi

We demonstrate the application of mixture density networks (MDNs) in the context of automated radiation therapy treatment planning. It is shown that an MDN can produce good predictions of dose distributions as well as reflect uncertain…

Medical Physics · Physics 2021-07-06 Viktor Nilsson , Hanna Gruselius , Tianfang Zhang , Geert De Kerf , Michaël Claessens

Purpose: This study quantifies the variation in dose-volume histogram (DVH) and normal tissue complication probability (NTCP) metrics for head-and-neck (HN) cancer patients when alternative organ-at-risk (OAR) delineations are used for…

The field of Radiation Oncology is uniquely positioned to benefit from the use of artificial intelligence to fully automate the creation of radiation treatment plans for cancer therapy. This time-consuming and specialized task combines…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Kuancheng Wang , Hai Siong Tan , Rafe Mcbeth

Conventional radiotherapy dose calculation algorithms are often computationally slow and non-differentiable, creating bottlenecks for online adaptive radiotherapy (ART) and limiting end-to-end automatic planning. Deep learning provides…

We propose to develop deep learning models that can predict Pareto optimal dose distributions by using any given set of beam angles, along with patient anatomy, as input to train the deep neural networks. We implement and compare two deep…

Medical Physics · Physics 2021-01-27 Gyanendra Bohara , Azar Sadeghnejad Barkousaraie , Steve Jiang , Dan Nguyen

We propose Deep-Motion-Net: an end-to-end graph neural network (GNN) architecture that enables 3D (volumetric) organ shape reconstruction from a single in-treatment kV planar X-ray image acquired at any arbitrary projection angle.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Isuru Wijesinghe , Michael Nix , Arezoo Zakeri , Alireza Hokmabadi , Bashar Al-Qaisieh , Ali Gooya , Zeike A. Taylor

Accurate segmentation of gross tumor volume (GTV) is essential for effective MRI-guided adaptive radiotherapy (MRgART) in head and neck cancer. However, manual segmentation of the GTV over the course of therapy is time-consuming and prone…

Image and Video Processing · Electrical Eng. & Systems 2024-12-03 Xin Tie , Weijie Chen , Zachary Huemann , Brayden Schott , Nuohao Liu , Tyler J. Bradshaw

In order to optimize the radiotherapy delivery for cancer treatment, especially when dealing with complex treatments such as Total Marrow and Lymph Node Irradiation (TMLI), the accurate contouring of the Planning Target Volume (PTV) is…

Computer Vision and Pattern Recognition · Computer Science 2024-02-12 Ricardo Coimbra Brioso , Damiano Dei , Nicola Lambri , Daniele Loiacono , Pietro Mancosu , Marta Scorsetti

We propose a fast beam orientation selection method, based on deep neural networks (DNN), capable of developing a plan comparable to those by the state-of-the-art column generation method. The novelty of Our model lies in its supervised…

Medical Physics · Physics 2019-12-23 Azar Sadeghnejad Barkousaraie , Olalekan Ogunmolu , Steve Jiang , Dan Nguyen

Lymph node metastasis (LNM) is a significant prognostic factor in patients with head and neck cancer, and the ability to predict it accurately is essential for treatment optimization. PET and CT imaging are routinely used for LNM…

Purpose The purpose of this study was to develop and evaluate a deep neural network (DNN) capable of generating flat-panel detector (FPD) images from digitally reconstructed radiography (DRR) images in lung cancer treatment, with the aim of…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Chisako Hayashi , Shinichiro Mori , Yasukuni Mori , Lim Taehyeung , Hiroki Suyari , Hitoshi Ishikawa

A good initialization of deep learning models is essential since it can help them converge better and faster. However, pretraining large models is unaffordable for many researchers, which makes a desired prediction for initial parameters…

Machine Learning · Computer Science 2024-05-28 Xinyu Zhou , Boris Knyazev , Alexia Jolicoeur-Martineau , Jie Fu