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The difference in restricted mean survival times between two groups is a clinically relevant summary measure. With observational data, there may be imbalances in confounding variables between the two groups. One approach to account for such…

Applications · Statistics 2014-10-17 Andrew Wey , David Vock , John Connett , Kyle Rudser

In survival analysis, estimating the fraction of 'immune' or 'cured' subjects who will never experience the event of interest, requires a sufficiently long follow-up period. A few statistical tests have been proposed to test the assumption…

Methodology · Statistics 2026-01-13 Tsz Pang Yuen , Eni Musta , Ingrid Van Keilegom

In recent years, mixture cure models have gained increasing popularity in survival analysis as an alternative to the Cox proportional hazards model, particularly in settings where a subset of patients is considered cured. The proportional…

Methodology · Statistics 2025-12-10 Fatih Kızılaslan , Valeria Vitelli

We address the problem of survival regression modelling with multivariate responses and nonlinear covariate effects. Our model extends the proportional hazards model by introducing several weakly-parametric elements: the marginal baseline…

Methodology · Statistics 2025-10-16 Na Lei , Mark A. Wolters , Wenqing He

We propose a deep generative approach to nonparametric estimation of conditional survival and hazard functions with right-censored data. The key idea of the proposed method is to first learn a conditional generator for the joint conditional…

Statistics Theory · Mathematics 2022-05-20 Xingyu Zhou , Wen Su , Changyu Liu , Yuling Jiao , Xingqiu Zhao , Jian Huang

The goals in clinical and cohort studies often include evaluation of the association of a time-dependent binary treatment or exposure with a survival outcome. Recently, several impactful studies targeted the association between…

Applications · Statistics 2019-01-24 Daniel Nevo , Tsuyoshi Hamada , Shuji Ogino , Molin Wang

Relative survival methodology deals with a competing risks survival model where the cause of death is unknown. This lack of information occurs regularly in population-based cancer studies. Non-parametric estimation of the net survival is…

Statistics Theory · Mathematics 2025-02-14 Oskar Laverny , Nathalie Grafféo , Roch Giorgi

This paper addresses the problem of identifying and estimating the causal effect of a treatment in the presence of unmeasured confounding and various types of right-censoring. Examples of these censoring mechanisms are administrative…

Statistics Theory · Mathematics 2025-03-19 Ilias Willems , Sara Rutten , Gilles Crommen , Ingrid Van Keilegom

Doubly robust estimators of causal effects are a popular means of estimating causal effects. Such estimators combine an estimate of the conditional mean of the outcome given treatment and confounders (the so-called outcome regression) with…

Methodology · Statistics 2019-01-17 David Benkeser , Weixin Cai , Mark J van der Laan

Conventional approaches to statistical inference preclude structures that facilitate incorporation of supplemental information acquired from similar circumstances. For example, the analysis of data obtained using perfusion computed…

Applications · Statistics 2015-11-18 Thomas A. Murray , Brian P. Hobbs , Bradley P. Carlin

In the mixture of experts model, a common assumption is the linearity between a response variable and covariates. While this assumption has theoretical and computational benefits, it may lead to suboptimal estimates by overlooking potential…

Methodology · Statistics 2025-04-17 Yeongsan Hwang , Byungtae Seo , Sangkon Oh

In this paper, we study the local constant and the local linear estimators of the conditional density function with right-censored data which exhibit some type of dependence. It is assumed that the observations form a stationary…

Statistics Theory · Mathematics 2019-07-12 Xianzhu Xiong , Meijuan Ou

In modeling survival data with a cure fraction, flexible modeling of covariate effects on the probability of cure has important medical implications, which aids investigators in identifying better treatments to cure. This paper studies a…

Methodology · Statistics 2019-11-06 Li-Hsiang Lin , Li-Shan Huang

In this paper, we first provide a review of different non-parametric estimators for the cumulative distribution function under left-censoring. We then propose a new estimator based on a non-parametric likelihood approach using reversed…

Statistics Theory · Mathematics 2023-07-11 N. Balakrishnan , Christian Paroissin , Magdalena Pereda Vivo

We propose a semiparametric data fusion framework for efficient inference on survival probabilities by integrating right-censored and current status data. Existing data fusion methods focus largely on fusing right-censored data only, while…

Methodology · Statistics 2025-09-15 Xiudi Li , Sijia Li

It is often of interest to study the association between covariates and the cumulative incidence of a right-censored time-to-event outcome. When time-varying covariates are measured on a fixed discrete time scale, it is desirable to account…

Methodology · Statistics 2026-04-28 Hongxiang Qiu , Marco Carone , Alex Luedtke , Peter B. Gilbert

Instrumental variable (IV) methods allow us the opportunity to address unmeasured confounding in causal inference. However, most IV methods are only applicable to discrete or continuous outcomes with very few IV methods for censored…

Methodology · Statistics 2020-09-30 Youjin Lee , Edward H. Kennedy , Nandita Mitra

Quantile regression is a powerful tool for detecting exposure-outcome associations given covariates across different parts of the outcome's distribution, but has two major limitations when the aim is to infer the effect of an exposure.…

In this paper, we study a novel approach for the estimation of quantiles when facing potential right censoring of the responses. Contrary to the existing literature on the subject, the adopted strategy of this paper is to tackle censoring…

Methodology · Statistics 2017-03-24 Mickaël De Backer , Anouar El Ghouch , Ingrid Van Keilegom

A novel mixture cure frailty model is introduced for handling censored survival data. Mixture cure models are preferable when the existence of a cured fraction among patients can be assumed. However, such models are heavily underexplored:…

Methodology · Statistics 2025-05-07 Fatih Kızılaslan , David Michael Swanson , Valeria Vitelli
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