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Single Shot MultiBox Detector (SSD) is one of the fastest algorithms in the current object detection field, which uses fully convolutional neural network to detect all scaled objects in an image. Deconvolutional Single Shot Detector (DSSD)…

Computer Vision and Pattern Recognition · Computer Science 2018-01-19 Liwen Zheng , Canmiao Fu , Yong Zhao

Spatial transcriptomics (ST) measures gene expression at fine-grained spatial resolution, offering insights into tissue molecular landscapes. Previous methods for spatial gene expression prediction typically crop spots of interest from…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Ruikun Zhang , Yan Yang , Liyuan Pan

Extended depth of field microscopy encodes axial information into a single acquisition through engineered point spread functions, but conventional and deep optics approaches are subject to degradation in scattering tissue. We introduce…

Understanding and manipulating two-dimensional materials for real-world applications remains challenging due to a lack of effective and high-throughput characterization techniques. Soft X-ray time-of-flight photoemission electron microscopy…

Materials Science · Physics 2025-12-22 Aashwin Mishra , Daniel Ratner , Quynh Nguyen

Limited throughput is a key challenge in in-vivo deep-tissue imaging using nonlinear optical microscopy. Point scanning multiphoton microscopy, the current gold standard, is slow especially compared to the wide-field imaging modalities used…

Image and Video Processing · Electrical Eng. & Systems 2022-12-26 Navodini Wijethilake , Mithunjha Anandakumar , Cheng Zheng , Peter T. C. So , Murat Yildirim , Dushan N. Wadduwage

The point spread function (PSF) of a translation invariant imaging system is its impulse response, which cannot always be measured directly. This is the case in high energy X-ray radiography, and it must be estimated from images of…

Numerical Analysis · Mathematics 2017-09-27 Kevin T. Joyce , Johnathan M. Bardsley , Aaron Luttman

Point-spread function (PSF) estimation in spatially undersampled images is challenging because large pixels average fine-scale spatial information. This is problematic when fine-resolution details are necessary, as in optimal photometry…

Instrumentation and Methods for Astrophysics · Physics 2021-02-03 Teresa Symons , Michael Zemcov , James Bock , Yun-Ting Cheng , Brendan Crill , Christopher Hirata , Stephanie Venuto

We propose a new scanning transmission electron microscopy (STEM) technique that can realize the three-dimensional (3D) characterization of vacancies, lighter and heavier dopants with high precision. Using multislice STEM imaging and…

Materials Science · Physics 2016-07-12 Jared M. Johnson , Soohyun Im , Jinwoo Hwang

We propose spatial semantic embedding network (SSEN), a simple, yet efficient algorithm for 3D instance segmentation using deep metric learning. The raw 3D reconstruction of an indoor environment suffers from occlusions, noise, and is…

Computer Vision and Pattern Recognition · Computer Science 2020-07-08 Dongsu Zhang , Junha Chun , Sang Kyun Cha , Young Min Kim

We propose a compact snapshot monocular depth estimation technique that relies on an engineered point spread function (PSF). Traditional approaches used in microscopic super-resolution imaging such as the Double-Helix PSF (DHPSF) are…

Image and Video Processing · Electrical Eng. & Systems 2022-08-05 Bhargav Ghanekar , Vishwanath Saragadam , Dushyant Mehra , Anna-Karin Gustavsson , Aswin Sankaranarayanan , Ashok Veeraraghavan

4D-STEM, in which the 2D diffraction plane is captured for each 2D scan position in the scanning transmission electron microscope (STEM) using a pixelated detector, is complementing and increasingly replacing existing imaging approaches.…

Instrumentation and Detectors · Physics 2022-07-27 Colum M. O'Leary , Benedikt Haas , Christoph T. Koch , Peter D. Nellist , Lewys Jones

Imaging through scattering is an important, yet challenging problem. Tremendous progress has been made by exploiting the deterministic input-output "transmission matrix" for a fixed medium. However, this "one-to-one" mapping is highly…

Image and Video Processing · Electrical Eng. & Systems 2018-09-27 Yunzhe Li , Yujia Xue , Lei Tian

X-ray Photoelectron Spectroscopy (XPS) is a crucial technique for material surface analysis, yet interpreting its spectra is often challenging for both human analysts and automated methods due to the prevalence of variable spectral shifts…

Materials Science · Physics 2026-03-06 Issa Saddiq , Yuxin Fan , Robert G. Palgrave , Mark A. Isaacs , David Morgan , Keith T. Butler

The point spread function (PSF) is fundamental to any type of microscopy, most importantly so for single-molecule localization techniques, where the exact PSF shape is crucial for precise molecule localization at the nanoscale. However,…

Deep learning has become an extremely effective tool for image classification and image restoration problems. Here, we apply deep learning to microscopy, and demonstrate how neural networks can exploit the chromatic dependence of the…

Optics · Physics 2018-07-05 Eran Hershko* , Lucien E. Weiss* , Tomer Michaeli , Yoav Shechtman

We present a semi-blind, spatially-variant deconvolution technique aimed at optical microscopy that combines a local estimation step of the point spread function (PSF) and deconvolution using a spatially variant, regularized Richardson-Lucy…

Computer Vision and Pattern Recognition · Computer Science 2019-05-21 Adrian Shajkofci , Michael Liebling

The key features of the MATPHOT algorithm for precise and accurate stellar photometry and astrometry using discrete Point Spread Functions are described. A discrete Point Spread Function (PSF) is a sampled version of a continuous PSF which…

Astrophysics · Physics 2009-11-11 Kenneth J. Mighell

Microscopy is one of the most essential imaging techniques in life sciences. High-quality images are required in order to solve (potentially life-saving) biomedical research problems. Many microscopy techniques do not achieve sufficient…

Computer Vision and Pattern Recognition · Computer Science 2018-10-24 Joris Roels , Jan Aelterman , Jonas De Vylder , Hiep Luong , Yvan Saeys , Wilfried Philips

In this paper we consider the problem of estimating a dense depth map from a set of sparse LiDAR points. We use techniques from compressed sensing and the recently developed Alternating Direction Neural Networks (ADNNs) to create a deep…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Nathaniel Chodosh , Chaoyang Wang , Simon Lucey

We present a new two-stage 3D object detection framework, named sparse-to-dense 3D Object Detector (STD). The first stage is a bottom-up proposal generation network that uses raw point cloud as input to generate accurate proposals by…

Computer Vision and Pattern Recognition · Computer Science 2019-07-25 Zetong Yang , Yanan Sun , Shu Liu , Xiaoyong Shen , Jiaya Jia
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