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Radiotherapy (RT) is a key component in the treatment of various cancers, including Acute Lymphocytic Leukemia (ALL) and Acute Myelogenous Leukemia (AML). Precise delineation of organs at risk (OARs) and target areas is essential for…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Ricardo Coimbra Brioso , Damiano Dei , Ciro Franzese , Nicola Lambri , Daniele Loiacono , Pietro Mancosu , Marta Scorsetti

Accurate segmentation of gross tumor volume (GTV) is essential for effective MRI-guided adaptive radiotherapy (MRgART) in head and neck cancer. However, manual segmentation of the GTV over the course of therapy is time-consuming and prone…

Image and Video Processing · Electrical Eng. & Systems 2024-12-03 Xin Tie , Weijie Chen , Zachary Huemann , Brayden Schott , Nuohao Liu , Tyler J. Bradshaw

Radiotherapy is the main treatment modality for nasopharynx cancer. Delineation of Gross Target Volume (GTV) from medical images such as CT and MRI images is a prerequisite for radiotherapy. As manual delineation is time-consuming and…

Image and Video Processing · Electrical Eng. & Systems 2021-01-28 Haochen Mei , Wenhui Lei , Ran Gu , Shan Ye , Zhengwentai Sun , Shichuan Zhang , Guotai Wang

Introduction: The present study on the development and evaluation of an automated brain tumor segmentation technique based on deep learning using the 3D U-Net model. Objectives: The objective is to leverage state-of-the-art convolutional…

Image and Video Processing · Electrical Eng. & Systems 2024-04-10 Suman Sourabh , Murugappan Valliappan , Narayana Darapaneni , Anwesh R P

In post-operative radiotherapy for prostate cancer, the cancerous prostate gland has been surgically removed, so the clinical target volume (CTV) to be irradiated encompasses the microscopic spread of tumor cells, which cannot be visualized…

Accurate delineation of the Clinical Target Volume (CTV) is essential for radiotherapy planning, yet remains time-consuming and difficult to assess, especially for complex treatments such as Total Marrow and Lymph Node Irradiation (TMLI).…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Ricardo Coimbra Brioso , Lorenzo Mondo , Damiano Dei , Nicola Lambri , Pietro Mancosu , Marta Scorsetti , Daniele Loiacono

Deep learning (DL) models for disease classification or segmentation from medical images are increasingly trained using transfer learning (TL) from unrelated natural world images. However, shortcomings and utility of TL for specialized…

Machine Learning · Statistics 2021-11-11 Sambuddha Ghosal , Pratik Shah

Efficient, reliable and reproducible target volume delineation is a key step in the effective planning of breast radiotherapy. However, post-operative breast target delineation is challenging as the contrast between the tumor bed volume…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Mahdieh Kazemimoghadam , Weicheng Chi , Asal Rahimi , Nathan Kim , Prasanna Alluri , Chika Nwachukwu , Weiguo Lu , Xuejun Gu

Background: Deep learning (DL)-based head and neck lymph node level (HN_LNL) autodelineation is of high relevance to radiotherapy research and clinical treatment planning but still underinvestigated in academic literature. Methods: An…

Deep learning-based automated contouring and treatment planning has been proven to improve the efficiency and accuracy of radiotherapy. However, conventional radiotherapy treatment planning process has the automated contouring and treatment…

Medical Physics · Physics 2024-12-02 Sangwook Kim , Aly Khalifa , Thomas G. Purdie , Chris McIntosh

$\bf{Purpose:}$ The goal of this study was (i) to use artificial intelligence to automate the traditionally labor-intensive process of manual segmentation of tumor regions in pathology slides performed by a pathologist and (ii) to validate…

The integration of machine learning in magnetic resonance imaging (MRI), specifically in neuroimaging, is proving to be incredibly effective, leading to better diagnostic accuracy, accelerated image analysis, and data-driven insights, which…

Automatic lymph node segmentation is the cornerstone for advances in computer vision tasks for early detection and staging of cancer. Traditional segmentation methods are constrained by manual delineation and variability in operator…

Image and Video Processing · Electrical Eng. & Systems 2025-06-11 Jingguo Qu , Xinyang Han , Man-Lik Chui , Yao Pu , Simon Takadiyi Gunda , Ziman Chen , Jing Qin , Ann Dorothy King , Winnie Chiu-Wing Chu , Jing Cai , Michael Tin-Cheung Ying

Transfer learning (TL) for medical image segmentation helps deep learning models achieve more accurate performances when there are scarce medical images. This study focuses on completing segmentation of the ribs from lung ultrasound images…

Image and Video Processing · Electrical Eng. & Systems 2021-10-06 Dorothy Cheng , Edmund Y. Lam

Tumor segmentation is a fundamental step for radiotherapy treatment planning. To define an accurate segmentation of the primary tumor (GTVp) of oropharyngeal cancer patients (OPC), simultaneous assessment of different image modalities is…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Alessia De Biase , Nanna Maria Sijtsema , Lisanne van Dijk , Johannes A. Langendijk , Peter van Ooijen

The implication of the thalamus in multiple neurological pathologies makes it a structure of interest for volumetric analysis. In the present work, we have designed and implemented a multimodal volumetric deep neural network for the…

Background: The aim of this study was to develop and evaluate a deep learning-based automated segmentation method for hepatic anatomy (i.e., parenchyma, tumors, portal vein, hepatic vein and biliary tree) from the hepatobiliary phase of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-21 Karin A. Olthof , Matteo Fusagli , Bianca Güttner , Tiziano Natali , Bram Westerink , Stefanie Speidel , Theo J. M. Ruers , Koert F. D. Kuhlmann , Andrey Zhylka

Precise automated delineation of post-operative gross tumor volume in glioblastoma cases is challenging and time-consuming owing to the presence of edema and the deformed brain tissue resulting from the surgical tumor resection. To develop…

Deep learning has quickly become the weapon of choice for brain lesion segmentation. However, few existing algorithms pre-configure any biological context of their chosen segmentation tissues, and instead rely on the neural network's…

Computer Vision and Pattern Recognition · Computer Science 2017-09-12 Andrew Beers , Ken Chang , James Brown , Emmett Sartor , CP Mammen , Elizabeth Gerstner , Bruce Rosen , Jayashree Kalpathy-Cramer

In drug discovery, accurate lung tumor segmentation is an important step for assessing tumor size and its progression using \textit{in-vivo} imaging such as MRI. While deep learning models have been developed to automate this process, the…

Image and Video Processing · Electrical Eng. & Systems 2024-11-11 Piotr Kaniewski , Fariba Yousefi , Yeman Brhane Hagos , Talha Qaiser , Nikolay Burlutskiy
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