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Suppose an online platform wants to compare a treatment and control policy, e.g., two different matching algorithms in a ridesharing system, or two different inventory management algorithms in an online retail site. Standard randomized…

Methodology · Statistics 2022-12-27 Peter Glynn , Ramesh Johari , Mohammad Rasouli

Protein function does not solely depend on structure but often relies on dynamical transitions between distinct conformations. Despite this fact, our ability to characterize or predict protein dynamics is substantially less developed…

Statistical Mechanics · Physics 2026-05-08 Michael A. Sauer , Souvik Mondal , Brandon Neff , Sthitadhi Maiti , Matthias Heyden

Many diverse phenomena in nature often inherently encode both short- and long-term temporal dependencies, which especially result from the direction of the flow of time. In this respect, we discovered experimental evidence suggesting that…

Artificial Intelligence · Computer Science 2025-02-11 Kyung Geun Kim , Byeong Tak Lee

Deep neural networks exhibit exceptional accuracy when they are trained and tested on the same data distributions. However, neural classifiers are often extremely brittle when confronted with domain shift---changes in the input distribution…

Computer Vision and Pattern Recognition · Computer Science 2019-04-15 Zuxuan Wu , Xin Wang , Joseph E. Gonzalez , Tom Goldstein , Larry S. Davis

Biological cells are able to accurately sense chemicals with receptors at their surfaces, allowing cells to move towards sources of attractant and away from sources of repellent. The accuracy of sensing chemical concentration is ultimately…

Subcellular Processes · Quantitative Biology 2015-05-14 Robert G. Endres , Ned S. Wingreen

This paper considers a distributed stochastic strongly convex optimization, where agents connected over a network aim to cooperatively minimize the average of all agents' local cost functions. Due to the stochasticity of gradient estimation…

Optimization and Control · Mathematics 2020-02-17 Jinlong Lei , Peng Yi , Jie Chen , Yiguang Hong

The phenomenon of data distribution evolving over time has been observed in a range of applications, calling the needs of adaptive learning algorithms. We thus study the problem of supervised gradual domain adaptation, where labeled data…

Machine Learning · Computer Science 2022-11-15 Jing Dong , Shiji Zhou , Baoxiang Wang , Han Zhao

We present a new adaptive algorithm for learning discrete distributions under distribution drift. In this setting, we observe a sequence of independent samples from a discrete distribution that is changing over time, and the goal is to…

Machine Learning · Computer Science 2024-03-11 Alessio Mazzetto

Machine learning in medical imaging during clinical routine is impaired by changes in scanner protocols, hardware, or policies resulting in a heterogeneous set of acquisition settings. When training a deep learning model on an initial…

Computer Vision and Pattern Recognition · Computer Science 2022-03-16 Matthias Perkonigg , Johannes Hofmanninger , Christian Herold , Helmut Prosch , Georg Langs

The response of microbes to external signals is mediated by biochemical networks with intrinsic time scales. These time scales give rise to a memory that impacts cellular behaviour. Here we study theoretically the role of cellular memory in…

Biological Physics · Physics 2020-02-14 Adam Gosztolai , Mauricio Barahona

Across diverse biological systems -- ranging from neural networks to intracellular signaling and genetic regulatory networks -- the information about changes in the environment is frequently encoded in the full temporal dynamics of the…

Quantitative Methods · Quantitative Biology 2020-07-01 Sarah A Cepeda-Humerez , Jakob Ruess , Gašper Tkačik

The assumption that training and testing samples are generated from the same distribution does not always hold for real-world machine-learning applications. The procedure of tackling this discrepancy between the training (source) and…

Machine Learning · Computer Science 2018-12-05 Debasmit Das , C. S. George Lee

Test-time adaptation (TTA) is a technique used to reduce distribution gaps between the training and testing sets by leveraging unlabeled test data during inference. In this work, we expand TTA to a more practical scenario, where the test…

Machine Learning · Computer Science 2023-03-06 Chenyan Wu , Yimu Pan , Yandong Li , James Z. Wang

Sampling is an important tool for estimating large, complex sums and integrals over high dimensional spaces. For instance, important sampling has been used as an alternative to exact methods for inference in belief networks. Ideally, we…

Artificial Intelligence · Computer Science 2013-01-18 Luis E. Ortiz , Leslie Pack Kaelbling

Co-evolutionary adaptive mechanisms are not only ubiquitous in nature, but also beneficial for the functioning of a variety of systems. We here consider an adaptive network of oscillators with a stochastic, fitness-based, rule of…

Physics and Society · Physics 2016-06-08 Young-Ho Eom , Stefano Boccaletti , Guido Caldarelli

We address control synthesis of stochastic discrete-time linear multi-agent systems under jointly chance-constrained collaborative signal temporal logic specifications in a distribution-free manner using available disturbance samples, which…

Systems and Control · Electrical Eng. & Systems 2025-08-27 Eleftherios E. Vlahakis , Lars Lindemann , Dimos V. Dimarogonas

In this paper, a novel time-based modulation scheme is proposed in the time-asynchronous channel for diffusion-based molecular communication systems with drift. Based on this modulation scheme, we demonstrate that the sample variance of…

Information Theory · Computer Science 2019-05-31 Qingchao Li

We introduce a model for dynamic networks, where the links or the strengths of the links change over time. We solve the model by mapping dynamic networks to the problem of directed percolation, where the direction corresponds to the…

Disordered Systems and Neural Networks · Physics 2015-05-13 Roni Parshani , Mark Dickison , Reuven Cohen , H. Eugene Stanley , Shlomo Havlin

Berg and Purcell [Biophys. J. 20, 193 (1977)] calculated how the accuracy of concentration sensing by single-celled organisms is limited by noise from the small number of counted molecules. Here we generalize their results to the sensing of…

Molecular Networks · Quantitative Biology 2011-11-28 Thierry Mora , Ned S. Wingreen

Test-Time Adaptation (TTA) enables pre-trained models to adjust to distribution shift by learning from unlabeled test-time streams. However, existing methods typically treat these streams as independent samples, overlooking the supervisory…

Machine Learning · Computer Science 2026-01-30 Young Kyung Kim , Oded Schlesinger , Qiangqiang Wu , J. Matías Di Martino , Guillermo Sapiro
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