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Accurate breast lesion risk estimation can significantly reduce unnecessary biopsies and help doctors decide optimal treatment plans. Most existing computer-aided systems rely solely on mammogram features to classify breast lesions. While…

Image and Video Processing · Electrical Eng. & Systems 2021-08-24 Hung Q. Vo , Pengyu Yuan , Tiancheng He , Stephen T. C. Wong , Hien V. Nguyen

Mammography is the most effective and available tool for breast cancer screening. However, the low positive predictive value of breast biopsy resulting from mammogram interpretation leads to approximately 70% unnecessary biopsies with…

Machine Learning · Computer Science 2013-06-04 Sahar A. Mokhtar , Alaa. M. Elsayad

The area under the receiver operating characteristic curve (AUC) is often used to evaluate the performance of clinical prediction models. Recently, a more refined strategy has been proposed to examine a partial area under the curve (pAUC),…

Applications · Statistics 2016-06-22 Travis Gerke , Svitlana Tyekucheva , Lorelei Mucci , Giovanni Parmigiani

Neuro-oncology poses unique challenges for machine learning due to heterogeneous data and tumor complexity, limiting the ability of foundation models (FMs) to generalize across cohorts. Existing FMs also perform poorly in predicting…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Moinak Bhattacharya , Angelica P. Kurtz , Fabio M. Iwamoto , Prateek Prasanna , Gagandeep Singh

Purpose To develop and demonstrate a novel tumor shell feature for predicting distant failure in non-small cell lung cancer (NSCLC) and cervical cancer (CC) patients. Patients and Methods The shell predictive model was constructed using…

Low-rank decomposition plays a central role in accelerating convolutional neural network (CNN), and the rank of decomposed kernel-tensor is a key parameter that determines the complexity and accuracy of a neural network. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2018-07-02 Hyeji Kim , Chong-Min Kyung

Motivation: Gene selection has become a common task in most gene expression studies. The objective of such research is often to identify the smallest possible set of genes that can still achieve good predictive performance. The problem of…

We suggest that deep learning can be used for pre-screening cancer by analyzing demographic and anthropometric information of patients, as well as biological markers obtained from routine blood samples and relative risks obtained from…

Machine Learning · Statistics 2023-02-07 Rolando Gonzales Martinez , Daan-Max van Dongen

Cardiovascular diseases (CVDs) are one of the most common chronic illnesses that affect peoples health. Early detection of CVDs can reduce mortality rates by preventing or reducing the severity of the disease. Machine learning algorithms…

Machine Learning · Computer Science 2021-06-17 Prasannavenkatesan Theerthagiri , Vidya J

The instability in the selection of models is a major concern with data sets containing a large number of covariates. We focus on stability selection which is used as a technique to improve variable selection performance for a range of…

Methodology · Statistics 2016-04-26 Md Hasinur Rahaman Khan , Anamika Bhadra , Tamanna Howlader

Recent advances in cancer research largely rely on new developments in microscopic or molecular profiling techniques offering high level of detail with respect to either spatial or molecular features, but usually not both. Here, we present…

Background: Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide. Accurate survival prediction is essential for treatment stratification, yet existing pathology foundation models often overlook…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Hikmat Khan , Usama Sajjad , Metin N. Gurcan , Anil Parwani , Wendy L. Frankel , Wei Chen , Muhammad Khalid Khan Niazi

The computationally cheap machine learning architecture of random feature maps can be viewed as a single-layer feedforward network in which the weights of the hidden layer are random but fixed and only the outer weights are learned via…

Machine Learning · Computer Science 2025-04-29 Pinak Mandal , Georg A. Gottwald , Nicholas Cranch

In machine learning one often assumes the data are independent when evaluating model performance. However, this rarely holds in practise. Geographic information data sets are an example where the data points have stronger dependencies among…

Applications · Statistics 2020-06-01 Jonne Pohjankukka , Tapio Pahikkala , Paavo Nevalainen , Jukka Heikkonen

We propose a new methodology for selecting and ranking covariates associated with a variable of interest in a context of high-dimensional data under dependence but few observations. The methodology successively intertwines the clustering of…

The reduced-rank regression model is a popular model to deal with multivariate response and multiple predictors, and is widely used in biology, chemometrics, econometrics, engineering, and other fields. In the reduced-rank regression…

Methodology · Statistics 2022-07-05 Canhong Wen , Qin Wang , Yuan Jiang

Physical symptoms caused by high stress commonly happen in our daily lives, leading to the importance of stress recognition systems. This study aims to improve stress classification by selecting appropriate features from Thermal-stress…

Neural and Evolutionary Computing · Computer Science 2021-09-09 Xuyang Shen , Jo Plested , Tom Gedeon

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

The intensive care units (ICUs) are responsible for generating a wealth of useful data in the form of Electronic Health Record (EHR). This data allows for the development of a prediction tool with perfect knowledge backing. We aimed to…

Machine Learning · Computer Science 2020-07-28 Saumil Maheshwari , Rohit Verma , Anupam Shukla , Ritu Tiwari , Rishu Garg

Cancer segmentation in whole-slide images is a fundamental step for viable tumour burden estimation, which is of great value for cancer assessment. However, factors like vague boundaries or small regions dissociated from viable tumour areas…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Yibao Sun , Giussepi Lopez , Yaqi Wang , Xingru Huang , Huiyu Zhou , Qianni Zhang