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Large language models (LLMs) achieve remarkable advancements by leveraging tools to interact with environments, a critical step toward generalized AI. However, the standard supervised fine-tuning (SFT) approach, which relies on large-scale…

Computation and Language · Computer Science 2025-08-27 Junjie Ye , Yilong Wu , Sixian Li , Yuming Yang , Zhiheng Xi , Tao Gui , Qi Zhang , Xuanjing Huang , Peng Wang , Zhongchao Shi , Jianping Fan , Zhengyin Du

Humans can learn to solve new tasks by inducing high-level strategies from example solutions to similar problems and then adapting these strategies to solve unseen problems. Can we use large language models to induce such high-level…

Machine Learning · Computer Science 2025-08-27 Weijia Xu , Nebojsa Jojic , Nicolas Le Roux

There is a growing interest in applying pre-trained large language models (LLMs) to planning problems. However, methods that use LLMs directly as planners are currently impractical due to several factors, including limited correctness of…

Artificial Intelligence · Computer Science 2023-11-03 Lin Guan , Karthik Valmeekam , Sarath Sreedharan , Subbarao Kambhampati

Model-driven engineering (MDE) simplifies software development through abstraction, yet challenges such as time constraints, incomplete domain understanding, and adherence to syntactic constraints hinder the design process. This paper…

Software Engineering · Computer Science 2024-10-17 Meriem Ben Chaaben , Lola Burgueño , Istvan David , Houari Sahraoui

Large language models (LLMs) have demonstrated remarkable capabilities in a wide range of tasks, yet their application to specialized domains remains challenging due to the need for deep expertise. Retrieval-Augmented generation (RAG) has…

Computation and Language · Computer Science 2025-09-30 Qinggang Zhang , Shengyuan Chen , Yuanchen Bei , Zheng Yuan , Huachi Zhou , Zijin Hong , Hao Chen , Yilin Xiao , Chuang Zhou , Junnan Dong , Yi Chang , Xiao Huang

Large language models (LLMs) process and predict sequences containing text to answer questions, and address tasks including document summarization, providing recommendations, writing software and solving quantitative problems. We provide a…

Numerical Analysis · Mathematics 2026-02-02 Ricardo Baptista , Andrew Stuart , Son Tran

While LLMs have shown great success in understanding and generating text in traditional conversational settings, their potential for performing ill-defined complex tasks is largely under-studied. Indeed, we are yet to conduct comprehensive…

Artificial Intelligence · Computer Science 2023-10-26 Shubhra Kanti Karmaker Santu , Dongji Feng

The pervasive deployment of Large Language Models-LLMs in various sectors often neglects the nuanced requirements of individuals and small organizations, who benefit more from models precisely tailored to their specific business contexts…

Computation and Language · Computer Science 2024-07-10 Jiaxi Cui , Wentao Zhang , Jing Tang , Xudong Tong , Zhenwei Zhang , Amie , Jing Wen , Rongsheng Wang , Pengfei Wu

The integration of Large Language Models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating drug discovery, and optimizing…

Quantitative Methods · Quantitative Biology 2024-09-10 Yizhen Zheng , Huan Yee Koh , Maddie Yang , Li Li , Lauren T. May , Geoffrey I. Webb , Shirui Pan , George Church

The success of large language models (LLMs) depends heavily on large-scale, high-quality instruction-following and reinforcement datasets. However, generating such data through human annotation is prohibitively time-consuming particularly…

Computation and Language · Computer Science 2026-02-02 Chenhua Shi , Gregor Macdonald , Bhavika Jalli , Wanlu Lei , John Zou , Mridul Jain , Joji Philip

In recent years, large language models (LLMs) have achieved state-of-the-art results in various biological sequence analysis tasks, such as sequence classification, structure prediction, and function prediction. Similar to advancements in…

Genomics · Quantitative Biology 2025-02-19 Wang Liang

We propose a method to teach multiple large language models (LLM) to collaborate by interleaving their generations at the token level. We model the decision of which LLM generates the next token as a latent variable. By optimizing the…

Computation and Language · Computer Science 2024-08-28 Shannon Zejiang Shen , Hunter Lang , Bailin Wang , Yoon Kim , David Sontag

This paper introduces a novel, multi-source framework for the relational validation of Large Language Models (LLMs). While existing benchmarks have demonstrated LLMs' proficiency at factual recall, their ability to understand and reproduce…

Social and Information Networks · Computer Science 2026-05-22 Moses Boudourides

Continual learning (CL) in large language models (LLMs) is an evolving domain that focuses on developing efficient and sustainable training strategies to adapt models to emerging knowledge and achieve robustness in dynamic environments. Our…

Computation and Language · Computer Science 2025-02-13 Çağatay Yıldız , Nishaanth Kanna Ravichandran , Nitin Sharma , Matthias Bethge , Beyza Ermis

Large Language models (LLMs) have emerged as powerful tools for addressing challenges across diverse domains. Notably, recent studies have demonstrated that large language models significantly enhance the efficiency of biomolecular analysis…

Computation and Language · Computer Science 2025-03-07 Jiyue Jiang , Zikang Wang , Yuheng Shan , Heyan Chai , Jiayi Li , Zixian Ma , Xinrui Zhang , Yu Li

Recent advancements in Large Language Models (LLMs) have demonstrated exceptional capabilities in natural language understanding and generation. While these models excel in general complex reasoning tasks, they still face challenges in…

Artificial Intelligence · Computer Science 2024-10-25 Graziano A. Manduzio , Federico A. Galatolo , Mario G. C. A. Cimino , Enzo Pasquale Scilingo , Lorenzo Cominelli

Cross-domain text classification aims to adapt models to a target domain that lacks labeled data. It leverages or reuses rich labeled data from the different but related source domain(s) and unlabeled data from the target domain. To this…

Computation and Language · Computer Science 2024-04-11 Yunlong Feng , Bohan Li , Libo Qin , Xiao Xu , Wanxiang Che

Large Language Models (LLMs) have emerged as powerful tools for accelerating scientific discovery, yet their static knowledge and hallucination issues hinder autonomous research applications. Recent advances integrate LLMs into agentic…

Artificial Intelligence · Computer Science 2025-12-23 Zeyu Xia , Jinzhe Ma , Congjie Zheng , Shufei Zhang , Yuqiang Li , Hang Su , P. Hu , Changshui Zhang , Xingao Gong , Wanli Ouyang , Lei Bai , Dongzhan Zhou , Mao Su

The large-scale pre-trained vision language models (VLM) have shown remarkable domain transfer capability on natural images. However, it remains unknown whether this capability can also apply to the medical image domain. This paper…

Computer Vision and Pattern Recognition · Computer Science 2023-02-08 Ziyuan Qin , Huahui Yi , Qicheng Lao , Kang Li

Spoken language understanding (SLU) tasks involve diverse skills that probe the information extraction, classification and/or generation capabilities of models. In this setting, task-specific training data may not always be available. While…

Computation and Language · Computer Science 2025-10-06 Neeraj Agrawal , Sriram Ganapathy
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