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Deep Neural Networks (DNNs) suffer from domain shift when the test dataset follows a distribution different from the training dataset. Domain generalization aims to tackle this issue by learning a model that can generalize to unseen…

Computer Vision and Pattern Recognition · Computer Science 2022-12-15 Yu Ding , Lei Wang , Bin Liang , Shuming Liang , Yang Wang , Fang Chen

Model-based approaches for image reconstruction, analysis and interpretation have made significant progress over the last decades. Many of these approaches are based on either mathematical, physical or biological models. A challenge for…

Computer Vision and Pattern Recognition · Computer Science 2019-10-01 Daniel Rueckert , Julia A. Schnabel

Recent artificial intelligence (AI) technologies show remarkable evolution in various academic fields and industries. However, in the real world, dynamic data lead to principal challenges for deploying AI models. An unexpected data change…

Machine Learning · Computer Science 2024-02-21 Jeng-Lin Li , Chih-Fan Hsu , Ming-Ching Chang , Wei-Chao Chen

Machine learning typically relies on the assumption that training and testing distributions are identical and that data is centrally stored for training and testing. However, in real-world scenarios, distributions may differ significantly…

Machine Learning · Computer Science 2025-08-22 Ying Li , Xingwei Wang , Rongfei Zeng , Praveen Kumar Donta , Ilir Murturi , Min Huang , Schahram Dustdar

Domain generalization (DG) focuses on transferring domain-invariant knowledge from multiple source domains (available at train time) to an, a priori, unseen target domain(s). This requires a class to be expressed in multiple domains for the…

Machine Learning · Computer Science 2023-06-02 Kimathi Kaai , Saad Hossain , Sirisha Rambhatla

Deep neural networks often suffer performance drops when test data distribution differs from training data. Domain Generalization (DG) aims to address this by focusing on domain-invariant features or augmenting data for greater diversity.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Nam Duong Tran , Nam Nguyen Phuong , Hieu H. Pham , Phi Le Nguyen , My T. Thai

Deep learning models are often evaluated in scenarios where the data distribution is different from those used in the training and validation phases. The discrepancy presents a challenge for accurately predicting the performance of models…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Shadi Alijani , Jamil Fayyad , Homayoun Najjaran

Modern deep neural networks struggle to transfer knowledge and generalize across diverse domains when deployed to real-world applications. Currently, domain generalization (DG) is introduced to learn a universal representation from multiple…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Yijun Yang , Shujun Wang , Lei Zhu , Lequan Yu

The generalization capability of machine learning models, which refers to generalizing the knowledge for an "unseen" domain via learning from one or multiple seen domain(s), is of great importance to develop and deploy machine learning…

Machine Learning · Computer Science 2022-02-17 Keyu Chen , Di Zhuang , J. Morris Chang

Unsupervised domain adaptation (UDA) aims to learn a model trained on source domain and performs well on unlabeled target domain. In medical image segmentation field, most existing UDA methods depend on adversarial learning to address the…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Shaolei Liu , Siqi Yin , Linhao Qu , Manning Wang

Mitotic figure detection is a challenging task in digital pathology that has a direct impact on therapeutic decisions. While automated methods often achieve acceptable results under laboratory conditions, they frequently fail in the…

Image and Video Processing · Electrical Eng. & Systems 2022-01-21 Jakob Dexl , Michaela Benz , Volker Bruns , Petr Kuritcyn , Thomas Wittenberg

The distribution shifts between training and test data typically undermine the performance of models. In recent years, lots of work pays attention to domain generalization (DG) where distribution shifts exist, and target data are unseen.…

Machine Learning · Computer Science 2024-01-05 Wang Lu , Jindong Wang , Yidong Wang , Xing Xie

Due to the cross-domain distribution shift aroused from diverse medical imaging systems, many deep learning segmentation methods fail to perform well on unseen data, which limits their real-world applicability. Recent works have shown the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-06 Shangqi Gao , Hangqi Zhou , Yibo Gao , Xiahai Zhuang

For medical image segmentation, imagine if a model was only trained using MR images in source domain, how about its performance to directly segment CT images in target domain? This setting, namely generalizable cross-modality segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Ziqi Zhou , Lei Qi , Xin Yang , Dong Ni , Yinghuan Shi

Purpose: Medical images acquired using different scanners and protocols can differ substantially in their appearance. This phenomenon, scanner domain shift, can result in a drop in the performance of deep neural networks which are trained…

Image and Video Processing · Electrical Eng. & Systems 2024-10-03 Brian Guo , Darui Lu , Gregory Szumel , Rongze Gui , Tingyu Wang , Nicholas Konz , Maciej A. Mazurowski

Deep learning has raised hopes and expectations as a general solution for many applications; indeed it has proven effective, but it also showed a strong dependence on large quantities of data. Luckily, it has been shown that, even when data…

Computer Vision and Pattern Recognition · Computer Science 2019-02-14 Fabio Maria Carlucci

Machine learning models are intrinsically vulnerable to domain shift between training and testing data, resulting in poor performance in novel domains. Domain generalization (DG) aims to overcome the problem by leveraging multiple source…

Computer Vision and Pattern Recognition · Computer Science 2022-10-27 Tingwei Wang , Da Li , Kaiyang Zhou , Tao Xiang , Yi-Zhe Song

Existing domain generalization aims to learn a generalizable model to perform well even on unseen domains. For many real-world machine learning applications, the data distribution often shifts gradually along domain indices. For example, a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-09 Qiuhao Zeng , Wei Wang , Fan Zhou , Charles Ling , Boyu Wang

Deep learning models in medical imaging face dual challenges: domain shift, where models perform poorly when deployed in settings different from their training environment, and class imbalance, where certain disease conditions are naturally…

Computer Vision and Pattern Recognition · Computer Science 2025-01-10 Lei Li , Xinglin Zhang , Jun Liang , Tao Chen

Domain generalization (DG) seeks to develop models that generalize well to unseen target domains, addressing the prevalent issue of distribution shifts in real-world applications. One line of research in DG focuses on aligning domain-level…

Machine Learning · Computer Science 2025-06-10 Yuen Chen , Haozhe Si , Guojun Zhang , Han Zhao