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The protein-protein interactions (PPIs) are crucial for understanding the majority of cellular processes. PPIs play important role in gene transcription regulation, cellular signaling, molecular basis of immune response and more. Moreover,…

Biomolecules · Quantitative Biology 2016-05-31 Maciej Pawel Ciemny , Mateusz Kurcinski , Andrzej Kolinski , Sebastian Kmiecik

Image dehazing poses significant challenges in environmental perception. Recent research mainly focus on deep learning-based methods with single modality, while they may result in severe information loss especially in dense-haze scenarios.…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Meng Yu , Te Cui , Haoyang Lu , Yufeng Yue

This work introduces VISY-REVE: a novel pipeline to validate image processing algorithms for Vision-Based Navigation. Traditional validation methods such as synthetic rendering or robotic testbed acquisition suffer from difficult setup and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Marius Neuhalfen , Jonathan Grzymisch , Manuel Sanchez-Gestido

Background: Cancers are highly heterogeneous with different subtypes. These subtypes often possess different genetic variants, present different pathological phenotypes, and most importantly, show various clinical outcomes such as varied…

Graphics · Computer Science 2014-07-09 Hao Ding , Chao Wang , Kun Huang , Raghu Machiraju

By profiting from recent developments in detector technologies, making it possible to access a stream of detection events with few-ns time resolutions, a new ptychographic workflow is established. This methodological framework, referred to…

Applied Physics · Physics 2026-03-27 Hoelen L. Lalandec Robert , Arno Annys , Tamazouzt Chennit , Jo Verbeeck

The estimation of the camera poses associated with a set of images commonly relies on feature matches between the images. In contrast, we are the first to address this challenge by using objectness regions to guide the pose estimation…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Matteo Taiana , Matteo Toso , Stuart James , Alessio Del Bue

Determining the localization of specific protein in human cells is important for understanding cellular functions and biological processes of underlying diseases. Among imaging techniques, high-throughput fluorescence microscopy imaging is…

Computer Vision and Pattern Recognition · Computer Science 2019-02-01 Yijun Tian

The prediction of protein interactions (CPIs) is crucial for the in-silico screening step in drug discovery. Recently, many end-to-end representation learning methods using deep neural networks have achieved significantly better performance…

Quantitative Methods · Quantitative Biology 2020-11-30 Jingtao Wang , Xi Li , Hua Zhang

Foundation models trained with self-supervised learning (SSL) on large-scale histological images have significantly accelerated the development of computational pathology. These models can serve as backbones for region-of-interest (ROI)…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Jiawen Li , Jiali Hu , Xitong Ling , Yongqiang Lv , Yuxuan Chen , Yizhi Wang , Tian Guan , Yifei Liu , Yonghong He

When studying multi-body protein complexes, biochemists use computational tools that can suggest hundreds or thousands of their possible spatial configurations. However, it is not feasible to experimentally verify more than only a very…

Human-Computer Interaction · Computer Science 2019-09-25 Katarína Furmanová , Adam Jurčík , Barbora Kozlíková , Helwig Hauser , Jan Byška

We present a new program able to perform visual structural analysis on 3D particle systems called PASYVAT (PArticle SYstem Visual Analysis Tool). More specifically, it can select multiple interparticle distance ranges from a radial…

Computational Physics · Physics 2017-02-06 Alfredo Metere , Tomas Oppelstrup , Mikhail Dzugutov , Anders Hast

Protein nanoclustering is a characteristic feature of their activated state and is essential for forming numerous subcellular structures. The formation of these nanoclusters is highly dependent on a series of post-translational…

Biological Physics · Physics 2025-11-13 Olivier Destaing , Bertrand Fourcade

The study of moving particles (e.g. molecules, virus, vesicles, organelles, or whole cells) is crucial to decipher a plethora of cellular mechanisms within physiological and pathological conditions. Powerful live-imaging approaches enable…

Numerical Analysis · Mathematics 2023-11-13 Eloina Corradi , Maurizio Tavelli , Marie-Laure Baudet , Walter Boscheri

The fast development of self-supervised learning lowers the bar learning feature representation from massive unlabeled data and has triggered a series of research on change detection of remote sensing images. Challenges in adapting…

Computer Vision and Pattern Recognition · Computer Science 2022-12-07 Meiqi Hu , Chen Wu , Liangpei Zhang

An optical microscopic examination of thinly cut stained tissue on glass slides prepared from a FFPE tissue blocks is the gold standard for tissue diagnostics. In addition, the diagnostic abilities and expertise of any pathologist is…

Signalling pathways are conserved across different species, therefore making yeast a model organism to study these via disruption of kinase activity. Yeast has 159 genes that encode protein kinases and phosphatases, and 136 of these have…

Molecular Networks · Quantitative Biology 2023-09-01 George A. Elder , Conrad Bessant

Coarse-graining is a powerful tool for extending the reach of dynamic models of proteins and other biological macromolecules. Topological coarse-graining, in which biomolecules or sets thereof are represented via graph structures, is a…

Biomolecules · Quantitative Biology 2021-09-15 Vy Duong , Elizabeth Diessner , Gianmarc Grazioli , Rachel W. Martin , Carter T. Butts

Virtual screening of small molecules against protein targets can accelerate drug discovery and development by predicting drug-target interactions (DTIs). However, structure-based methods like molecular docking are too slow to allow for…

The rapid iteration and widespread dissemination of deepfake technology have posed severe challenges to information security, making robust and generalizable detection of AI-generated forged images increasingly important. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Zhilin Tu , Kemou Li , Fengpeng Li , Jianwei Fei , Jiamin Zhang , Haiwei Wu

Remote photoplethysmography (rPPG) enables contactless measurement of heart rate and other vital signs by analyzing subtle color variations in facial skin induced by cardiac pulsation. Current rPPG methods are mainly based on either…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Junzhe Cao , Bo Zhao , Zhiyi Niu , Dan Guo , Yue Sun , Haochen Liang , Yong Xu , Zitong YU