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Segmentation in medical imaging is an essential and often preliminary task in the image processing chain, driving numerous efforts towards the design of robust segmentation algorithms. Supervised learning methods achieve excellent…

Image and Video Processing · Electrical Eng. & Systems 2024-04-03 Pierre Rougé , Pierre-Henri Conze , Nicolas Passat , Odyssée Merveille

Deep learning provides us with powerful methods to perform nucleus or cell segmentation with unprecedented quality. However, these methods usually require large training sets of manually annotated images, which are tedious and expensive to…

Image and Video Processing · Electrical Eng. & Systems 2023-01-11 Thomas Bonte , Maxence Philbert , Emeline Coleno , Edouard Bertrand , Arthur Imbert , Thomas Walter

Medical image segmentation is crucial for clinical applications, but it is frequently disrupted by noisy annotations and ambiguous anatomical boundaries, limiting its application in real-world scenarios. Existing methods often directly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Chenyu Mu , Guihai Chen , Xun Yang , Erkun Yang , Cheng Deng

Manually annotating object segmentation masks is very time-consuming. While interactive segmentation methods offer a more efficient alternative, they become unaffordable at a large scale because the cost grows linearly with the number of…

Computer Vision and Pattern Recognition · Computer Science 2021-10-07 Dim P. Papadopoulos , Ethan Weber , Antonio Torralba

Labeled datasets for semantic segmentation are imperfect, especially in medical imaging where borders are often subtle or ill-defined. Little work has been done to analyze the effect that label errors have on the performance of segmentation…

Computer Vision and Pattern Recognition · Computer Science 2018-09-25 Nicholas Heller , Joshua Dean , Nikolaos Papanikolopoulos

Imperfect labels limit the quality of predictions learned by deep neural networks. This is particularly relevant in medical image segmentation, where reference annotations are difficult to collect and vary significantly even across expert…

Computer Vision and Pattern Recognition · Computer Science 2021-07-07 Eugene Vorontsov , Samuel Kadoury

Large, fine-grained image segmentation datasets, annotated at pixel-level, are difficult to obtain, particularly in medical imaging, where annotations also require expert knowledge. Weakly-supervised learning can train models by relying on…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Gabriele Valvano , Andrea Leo , Sotirios A. Tsaftaris

Generalization is an important attribute of machine learning models, particularly for those that are to be deployed in a medical context, where unreliable predictions can have real world consequences. While the failure of models to…

Computer Vision and Pattern Recognition · Computer Science 2022-12-14 Brennan Nichyporuk , Jillian Cardinell , Justin Szeto , Raghav Mehta , Jean-Pierre R. Falet , Douglas L. Arnold , Sotirios A. Tsaftaris , Tal Arbel

Although numerous improvements have been made in the field of image segmentation using convolutional neural networks, the majority of these improvements rely on training with larger datasets, model architecture modifications, novel loss…

Computer Vision and Pattern Recognition · Computer Science 2019-07-11 Saied Asgari Taghanaki , Kumar Abhishek , Ghassan Hamarneh

This paper shows the machine learning system which performs instance segmentation of cytological images in veterinary medicine. Eleven cell types were used directly and indirectly in the experiments, including damaged and unrecognized…

The Segment Anything Model (SAM) exhibits a capability to segment a wide array of objects in natural images, serving as a versatile perceptual tool for various downstream image segmentation tasks. In contrast, medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Yizhe Zhang , Tao Zhou , Shuo Wang , Ye Wu , Pengfei Gu , Danny Z. Chen

Recently deep neural networks, which require a large amount of annotated samples, have been widely applied in nuclei instance segmentation of H\&E stained pathology images. However, it is inefficient and unnecessary to label all pixels for…

Computer Vision and Pattern Recognition · Computer Science 2022-12-21 Wei Lou , Haofeng Li , Guanbin Li , Xiaoguang Han , Xiang Wan

Evidence suggests that networks trained on large datasets generalize well not solely because of the numerous training examples, but also class diversity which encourages learning of enriched features. This raises the question of whether…

High-quality pixel-level annotations are essential for the semantic segmentation of remote sensing imagery. However, such labels are expensive to obtain and often affected by noise due to the labor-intensive and time-consuming nature of…

Deep learning has shown great promise in the ability to automatically annotate organs in magnetic resonance imaging (MRI) scans, for example, of the brain. However, despite advancements in the field, the ability to accurately segment…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Cosmin Ciausu , Deepa Krishnaswamy , Benjamin Billot , Steve Pieper , Ron Kikinis , Andrey Fedorov

Medical image segmentation annotation suffers from inter-rater variability (IRV) due to differences in annotators' expertise and the inherent blurriness of medical images. Standard approaches that simply average expert labels are flawed, as…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Chen Zhong , Yuxuan Yang , Xinyue Zhang , Ruohan Ma , Yong Guo , Gang Li , Jupeng Li

In-vitro tests are an alternative to animal testing for the toxicity of medical devices. Detecting cells as a first step, a cell expert evaluates the growth of cells according to cytotoxicity grade under the microscope. Thus, human fatigue…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Marawan Elbatel , Christina Bornberg , Manasi Kattel , Enrique Almar , Claudio Marrocco , Alessandro Bria

Accurate identification of breast masses is crucial in diagnosing breast cancer; however, it can be challenging due to their small size and being camouflaged in surrounding normal glands. Worse still, it is also expensive in clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Xinyu Xiong , Churan Wang , Wenxue Li , Guanbin Li

Nuclei segmentation is a fundamental task in histopathology image analysis. Typically, such segmentation tasks require significant effort to manually generate accurate pixel-wise annotations for fully supervised training. To alleviate such…

Computer Vision and Pattern Recognition · Computer Science 2020-07-13 Hui Qu , Pengxiang Wu , Qiaoying Huang , Jingru Yi , Zhennan Yan , Kang Li , Gregory M. Riedlinger , Subhajyoti De , Shaoting Zhang , Dimitris N. Metaxas

This paper explores the use of a soft ground-truth mask ("soft mask'') to train a Fully Convolutional Neural Network (FCNN) for segmentation of Multiple Sclerosis (MS) lesions. Detection and segmentation of MS lesions is a complex task…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Eytan Kats , Jacob Goldberger , Hayit Greenspan