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Large Language Models offer impressive language capabilities but suffer from well-known limitations, including hallucinations, biases, privacy concerns, and high computational costs. These issues are largely driven by the combination of…

Computation and Language · Computer Science 2025-09-03 Jaime Collado-Montañez , L. Alfonso Ureña-López , Arturo Montejo-Ráez

As the knowledge of large language models (LLMs) becomes outdated over time, there is a growing need for efficient methods to update them, especially when injecting proprietary information. Our study reveals that comprehension-intensive…

Computation and Language · Computer Science 2025-05-26 Essa Jan , Moiz Ali , Muhammad Saram Hassan , Fareed Zaffar , Yasir Zaki

Large Language Models (LLMs) have emerged as powerful tools in the field of Natural Language Processing (NLP) and have recently gained significant attention in the domain of Recommendation Systems (RS). These models, trained on massive…

Information Retrieval · Computer Science 2024-06-19 Likang Wu , Zhi Zheng , Zhaopeng Qiu , Hao Wang , Hongchao Gu , Tingjia Shen , Chuan Qin , Chen Zhu , Hengshu Zhu , Qi Liu , Hui Xiong , Enhong Chen

Large language models (LLMs) such as ChatGPT have gained considerable interest across diverse research communities. Their notable ability for text completion and generation has inaugurated a novel paradigm for language-interfaced problem…

Quantitative Methods · Quantitative Biology 2024-02-22 Hengchuang Yin , Zhonghui Gu , Fanhao Wang , Yiparemu Abuduhaibaier , Yanqiao Zhu , Xinming Tu , Xian-Sheng Hua , Xiao Luo , Yizhou Sun

Large language models (LLMs) have demonstrated remarkable proficiency in understanding and generating responses to complex queries through large-scale pre-training. However, the efficacy of these models in memorizing and reasoning among…

Computation and Language · Computer Science 2024-02-23 Qiyuan He , Yizhong Wang , Wenya Wang

Knowledge Tracing (KT) is a research field that aims to estimate a student's knowledge state through learning interactions-a crucial component of Intelligent Tutoring Systems (ITSs). Despite significant advancements, no current KT models…

Computers and Society · Computer Science 2024-12-13 Yongwan Cho , Rabia Emhamed AlMamlook , Tasnim Gharaibeh

Large Language Models (LLMs) inherently encode a wealth of knowledge within their parameters through pre-training on extensive corpora. While prior research has delved into operations on these parameters to manipulate the underlying…

Computation and Language · Computer Science 2024-05-09 Ming Zhong , Chenxin An , Weizhu Chen , Jiawei Han , Pengcheng He

A Language Model is a term that encompasses various types of models designed to understand and generate human communication. Large Language Models (LLMs) have gained significant attention due to their ability to process text with human-like…

Computation and Language · Computer Science 2024-06-12 Sylvio Barbon Junior , Paolo Ceravolo , Sven Groppe , Mustafa Jarrar , Samira Maghool , Florence Sèdes , Soror Sahri , Maurice Van Keulen

Large Language Models (LLMs) have demonstrated exceptional performance in general knowledge and reasoning tasks across various domains. However, their effectiveness in specialized scientific fields like Chemical and Biological Engineering…

Artificial Intelligence · Computer Science 2025-05-20 Gaurab Sarkar , Sougata Saha

Neural language models are black-boxes--both linguistic patterns and factual knowledge are distributed across billions of opaque parameters. This entangled encoding makes it difficult to reliably inspect, verify, or update specific facts.…

Due to an exponential increase in published research articles, it is impossible for individual scientists to read all publications, even within their own research field. In this work, we investigate the use of large language models (LLMs)…

Deep neural-network-based language models (LMs) are increasingly applied to large-scale protein sequence data to predict protein function. However, being largely black-box models and thus challenging to interpret, current protein LM…

Quantitative Methods · Quantitative Biology 2024-08-06 Mai Ha Vu , Rahmad Akbar , Philippe A. Robert , Bartlomiej Swiatczak , Victor Greiff , Geir Kjetil Sandve , Dag Trygve Truslew Haug

The recent success of large language models (LLMs) trained on static, pre-collected, general datasets has sparked numerous research directions and applications. One such direction addresses the non-trivial challenge of integrating…

Machine Learning · Computer Science 2024-11-26 Haizhou Shi , Zihao Xu , Hengyi Wang , Weiyi Qin , Wenyuan Wang , Yibin Wang , Zifeng Wang , Sayna Ebrahimi , Hao Wang

Multimodal large language models (MLLMs) have made impressive progress in many applications in recent years. However, chemical MLLMs that can handle cross-modal understanding and generation remain underexplored. To fill this gap, we propose…

Machine Learning · Computer Science 2025-08-05 Qian Tan , Dongzhan Zhou , Peng Xia , Wanhao Liu , Wanli Ouyang , Lei Bai , Yuqiang Li , Tianfan Fu

Integrating external knowledge into large language models (LLMs) presents a promising solution to overcome the limitations imposed by their antiquated and static parametric memory. Prior studies, however, have tended to over-reliance on…

Computation and Language · Computer Science 2024-05-30 Hao Zhang , Yuyang Zhang , Xiaoguang Li , Wenxuan Shi , Haonan Xu , Huanshuo Liu , Yasheng Wang , Lifeng Shang , Qun Liu , Yong Liu , Ruiming Tang

Large language models (LLMs) have ushered in a new era for processing complex information in various fields, including science. The increasing amount of scientific literature allows these models to acquire and understand scientific…

Computation and Language · Computer Science 2024-08-21 Huy Quoc To , Ming Liu , Guangyan Huang

Large Language Models are cognitively biased judges. Large Language Models (LLMs) have recently been shown to be effective as automatic evaluators with simple prompting and in-context learning. In this work, we assemble 15 LLMs of four…

Computation and Language · Computer Science 2024-09-26 Ryan Koo , Minhwa Lee , Vipul Raheja , Jong Inn Park , Zae Myung Kim , Dongyeop Kang

Although large language models (LLMs) store vast amount of knowledge in their parameters, they still have limitations in the memorization and utilization of certain knowledge, leading to undesired behaviors such as generating untruthful and…

Computation and Language · Computer Science 2025-05-28 Moxin Li , Yong Zhao , Wenxuan Zhang , Shuaiyi Li , Wenya Xie , See-Kiong Ng , Tat-Seng Chua , Yang Deng

We introduce the framework of "social learning" in the context of large language models (LLMs), whereby models share knowledge with each other in a privacy-aware manner using natural language. We present and evaluate two approaches for…

Machine Learning · Computer Science 2024-02-09 Amirkeivan Mohtashami , Florian Hartmann , Sian Gooding , Lukas Zilka , Matt Sharifi , Blaise Aguera y Arcas