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We consider a parabolic non-local free boundary problem that has been derived as a limit of a bulk-surface reaction-diffusion system which models cell polarization. The authors have justified the well-posedness of this problem and have…

Analysis of PDEs · Mathematics 2023-04-24 Anna Logioti , Barbara Niethammer , Matthias Röger , Juan J. L. Velázquez

In this paper we study a mass-constrained free boundary problem modeling cell polarization, in the regime where the mass is small. In the generic case of a signal with nondegenerate maxima, we prove that the solution converges locally to a…

Analysis of PDEs · Mathematics 2026-05-06 Sebastián Flores Sepúlveda , Barbara Niethammer , Juan J. L. Velázquez

The amplification of an external signal is a key step in direction sensing of biological cells. We consider a simple model for the response to a time-depending signal, which was previously proposed by the last three authors. The model…

Analysis of PDEs · Mathematics 2020-06-30 Anna Logioti , Barbara Niethammer , Matthias Röger , Juan J. L. Velázquez

A mutualist model with nonlocal diffusions and a free boundary is first considered. We prove that this problem has a unique solution defined $t\ge0$, and its dynamics are governed by a spreading-vanishing dichotomy. Some criteria for…

Analysis of PDEs · Mathematics 2021-10-28 Lei Li , Mingxin Wang

This paper studies asymptotic behavior of solutions of a free boundary problem modeling the growth of tumors with two species of cells: proliferating cells and quiecent cells. In previous literatures it has been proved that this problem has…

Analysis of PDEs · Mathematics 2013-03-18 Shangbin Cui

We consider a coupled bulk-surface system of partial differential equations with nonlinear coupling modelling receptor-ligand dynamics. The model arises as a simplification of a mathematical model for the reaction between cell surface…

Analysis of PDEs · Mathematics 2016-11-08 Charles M. Elliott , Thomas Ranner , Chandrasekhar Venkataraman

We derive various novel free boundary problems as limits of a coupled bulk-surface reaction-diffusion system modelling ligand-receptor dynamics on evolving domains. These limiting free boundary problems may be formulated as Stefan-type…

Analysis of PDEs · Mathematics 2024-07-24 Amal Alphonse , Diogo Caetano , Charles M. Elliott , Chandrasekhar Venkataraman

In this paper we present an individual-based mechanical model that describes the dynamics of two contiguous cell populations with different proliferative and mechanical characteristics. An off-lattice modelling approach is considered…

Analysis of PDEs · Mathematics 2020-01-14 Tommaso Lorenzi , Philip J. Murray , Mariya Ptashnyk

In this paper, we study a competitive model involving two species. When the competition is strong enough, the two species are separated by a free boundary. If the initial data has a positive bound at infinity. We prove that the solution…

Analysis of PDEs · Mathematics 2013-12-17 Jian Yang

We provide rigorous asymptotic models for the free boundary Darcy and Forchheimer problem under the assumption of weak nonlinear interaction, in a regime in which the steepness parameter of the interface is considered to be very small. The…

Analysis of PDEs · Mathematics 2019-08-15 Rafael Granero-Belinchón , Stefano Scrobogna

We study the motion of phase interfaces in a diffusive lattice equation with bistable nonlinearity and derive a free boundary problem with hysteresis to describe the macroscopic evolution in the parabolic scaling limit. The first part of…

Analysis of PDEs · Mathematics 2015-03-03 Michael Helmers , Michael Herrmann

We consider an elliptic-parabolic free boundary problem that models the fluid flow through a partially saturated porous medium. The free boundary arises as the interface separating the saturated and unsaturated regions. Our main goal is to…

Analysis of PDEs · Mathematics 2025-08-20 Dennis Kriventsov , María Soria-Carro

In this work, we investigate the dynamics of a non-local model describing spontaneous cell polarisation. It consists in a drift-diffusion equation set in the half-space, with the coupling involving the trace value on the boundary. We…

Analysis of PDEs · Mathematics 2011-05-24 Vincent Calvez , Rhoda Hawkins , Nicolas Meunier , Raphael Voituriez

We are concerned with the global bifurcation analysis of positive solutions to free boundary problems arising in plasma physics. We show that in general, in the sense of domain variations, the following alternative holds: either the shape…

Analysis of PDEs · Mathematics 2021-12-13 Daniele Bartolucci , Yeyao Hu , Aleks Jevnikar , Wen Yang

In this article we establish the exact growth of the solution to the singular quasilinear p-parabolic free boundary problem in non-divergence form near the free boundary from which follows its porosity.

Analysis of PDEs · Mathematics 2018-10-09 G. C. Ricarte

We study a class of free boundary problems of ecological models with nonlocal and local diffusions, which are natural extensions of free boundary problems of reaction diffusion systems in there local diffusions are used to describe the…

Analysis of PDEs · Mathematics 2019-09-17 Jianping Wang , Mingxin Wang

We consider a free boundary model of epithelial cell migration with logistic growth and nonlinear diffusion induced by mechanical interactions. Using numerical simulations, phase plane and perturbation analysis, we find and analyse…

Pattern Formation and Solitons · Physics 2020-10-05 Ryan J Murphy , Pascal R Buenzli , Ruth E Baker , Matthew J Simpson

We study a parabolic free boundary problem, arising from a model for the propagation of equi-diffusional premixed flames with high activation energy. If an initial data is compactly supported, then the solution vanishes in a finite time,…

Analysis of PDEs · Mathematics 2019-11-19 Rubin Abrams , Sunhi Choi

This article is concerned with a system of semilinear parabolic equations with two free boundaries describing the spreading fronts of the invasive species in a mutualistic ecological model. The local existence and uniqueness of a classical…

Analysis of PDEs · Mathematics 2014-05-20 Mei Li

We consider the free boundary problem for the plasma-vacuum interface in ideal compressible magnetohydrodynamics (MHD). In the plasma region, the flow is governed by the usual compressible MHD equations, while in the vacuum region we…

Analysis of PDEs · Mathematics 2014-07-22 Davide Catania , Marcello D'Abbicco , Paolo Secchi
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