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Identifying predictive factors for an outcome of interest via a multivariable analysis is often difficult when the data set is small. Combining data from different medical centers into a single (larger) database would alleviate this…

Applications · Statistics 2024-03-12 Marianne A. Jonker , Hassan Pazira , Anthony CC Coolen

In cancer research, overall survival and progression free survival are often analyzed with the Cox model. To estimate accurately the parameters in the model, sufficient data and, more importantly, sufficient events need to be observed. In…

Modelling a complex system is almost invariably a challenging task. The incorporation of experimental observations can be used to improve the quality of a model, and thus to obtain better predictions about the behavior of the corresponding…

Computational Physics · Physics 2015-11-24 Massimiliano Bonomi , Carlo Camilloni , Andrea Cavalli , Michele Vendruscolo

Hierarchical models are versatile tools for joint modeling of data sets arising from different, but related, sources. Fully Bayesian inference may, however, become computationally prohibitive if the source-specific data models are complex,…

Computation · Statistics 2016-05-06 Ritabrata Dutta , Paul Blomstedt , Samuel Kaski

We are interested in estimating the effect of a treatment applied to individuals at multiple sites, where data is stored locally for each site. Due to privacy constraints, individual-level data cannot be shared across sites; the sites may…

Machine Learning · Computer Science 2023-04-04 Ruoxuan Xiong , Allison Koenecke , Michael Powell , Zhu Shen , Joshua T. Vogelstein , Susan Athey

Data analysis based on information from several sources is common in economic and biomedical studies. This setting is often referred to as the data fusion problem, which differs from traditional missing data problems since no complete data…

Methodology · Statistics 2022-04-07 Wei Li , Shanshan Luo , Wangli Xu

The limited representation of minorities and disadvantaged populations in large-scale clinical and genomics research has become a barrier to translating precision medicine research into practice. Due to heterogeneity across populations,…

Machine Learning · Statistics 2021-08-30 Sai Li , Tianxi Cai , Rui Duan

Integrating data from multiple heterogeneous sources has become increasingly popular to achieve a large sample size and diverse study population. This paper reviews development in causal inference methods that combines multiple datasets…

Methodology · Statistics 2021-10-05 Xu Shi , Ziyang Pan , Wang Miao

Many analyses require linking records from two databases comprising overlapping sets of individuals. In the absence of unique identifiers, the linkage procedure often involves matching on a set of categorical variables, such as…

Applications · Statistics 2017-06-12 Nicole M. Dalzell , Jerome P. Reiter

This paper presents a novel nonlinear regression model for estimating heterogeneous treatment effects from observational data, geared specifically towards situations with small effect sizes, heterogeneous effects, and strong confounding.…

Methodology · Statistics 2019-11-14 P. Richard Hahn , Jared S. Murray , Carlos Carvalho

Federated learning faces huge challenges from model overfitting due to the lack of data and statistical diversity among clients. To address these challenges, this paper proposes a novel personalized federated learning method via Bayesian…

Machine Learning · Computer Science 2022-06-17 Xu Zhang , Yinchuan Li , Wenpeng Li , Kaiyang Guo , Yunfeng Shao

Bayesian inference is a powerful tool for combining information in complex settings, a task of increasing importance in modern applications. However, Bayesian inference with a flawed model can produce unreliable conclusions. This review…

Methodology · Statistics 2023-05-22 David J. Nott , Christopher Drovandi , David T. Frazier

We empirically show that Bayesian inference can be inconsistent under misspecification in simple linear regression problems, both in a model averaging/selection and in a Bayesian ridge regression setting. We use the standard linear model,…

Statistics Theory · Mathematics 2018-10-30 Peter Grünwald , Thijs van Ommen

The estimation of heterogeneous treatment effects in the potential outcome setting is biased when there exists model misspecification or unobserved confounding. As these biases are unobservable, what model to use when remains a critical…

Methodology · Statistics 2024-05-09 Shonosuke Sugasawa , Kosaku Takanashi , Kenichiro McAlinn , Edoardo M. Airoldi

Federated Learning (FL) involves training a model over a dataset distributed among clients, with the constraint that each client's dataset is localized and possibly heterogeneous. In FL, small and noisy datasets are common, highlighting the…

Machine Learning · Computer Science 2024-01-11 Mohsin Hasan , Guojun Zhang , Kaiyang Guo , Xi Chen , Pascal Poupart

Decentralized data sources are prevalent in real-world applications, posing a formidable challenge for causal inference. These sources cannot be consolidated into a single entity owing to privacy constraints. The presence of dissimilar data…

Machine Learning · Computer Science 2024-05-31 Thanh Vinh Vo , Young lee , Tze-Yun Leong

Bayesian causal inference offers a principled approach to policy evaluation of proposed interventions on mediators or time-varying exposures. We outline a general approach to the estimation of causal quantities for settings with…

Methodology · Statistics 2019-02-28 Leah Comment , Brent A. Coull , Corwin Zigler , Linda Valeri

Given a supervised machine learning problem where the training set has been subject to a known sampling bias, how can a model be trained to fit the original dataset? We achieve this through the Bayesian inference framework by altering the…

Machine Learning · Statistics 2022-03-16 Max Sklar

Bayesian model comparison is often based on the posterior distribution over the set of compared models. This distribution is often observed to concentrate on a single model even when other measures of model fit or forecasting ability…

Statistics Theory · Mathematics 2020-03-10 Oscar Oelrich , Shutong Ding , Måns Magnusson , Aki Vehtari , Mattias Villani

Nested error regression models are useful tools for analysis of grouped data, especially in the case of small area estimation. This paper suggests a nested error regression model using uncertain random effects in which the random effect in…

Methodology · Statistics 2017-02-28 Shonosuke Sugasawa , Tatsuya Kubokawa
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