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Molecular Property Prediction (MPP) is a fundamental problem in drug discovery that has recently attracted growing attention. Large Language Models (LLMs), known for their impressive proficiency across domains, show promise as generalist…

Machine Learning · Computer Science 2026-05-28 Khiem Le , Sreejata Dey , Marcos Martínez Galindo , Vanessa Lopez , Ting Hua , Nitesh V. Chawla , Hoang Thanh Lam

Recent research has explored distilling knowledge from large language models (LLMs) to optimize retriever models, especially within the retrieval-augmented generation (RAG) framework. However, most existing training methods rely on…

Information Retrieval · Computer Science 2024-06-19 Zizhong Li , Haopeng Zhang , Jiawei Zhang

Ensuring that Large Language Models (LLMs) generate text representative of diverse sub-populations is essential, particularly when key concepts related to under-represented groups are scarce in the training data. We address this challenge…

Computation and Language · Computer Science 2024-12-17 Sabit Hassan , Anthony Sicilia , Malihe Alikhani

Music Recommender Systems (MRS) have long relied on an information-retrieval framing, where progress is measured mainly through accuracy on retrieval-oriented subtasks. While effective, this reductionist paradigm struggles to address the…

Information Retrieval · Computer Science 2025-11-21 Elena V. Epure , Yashar Deldjoo , Bruno Sguerra , Markus Schedl , Manuel Moussallam

News recommender systems play a critical role in mitigating the information overload problem. In recent years, due to the successful applications of large language model technologies, researchers have utilized Discriminative Large Language…

Information Retrieval · Computer Science 2025-02-25 Rongyao Wang , Veronica Liesaputra , Zhiyi Huang

Sequential recommendation aims to predict users' next interaction with items based on their past engagement sequence. Recently, the advent of Large Language Models (LLMs) has sparked interest in leveraging them for sequential…

Information Retrieval · Computer Science 2024-05-07 Jiayi Liao , Sihang Li , Zhengyi Yang , Jiancan Wu , Yancheng Yuan , Xiang Wang , Xiangnan He

Accurate clinical diagnosis requires extensive domain knowledge and complex clinical reasoning capabilities. Although large language models (LLMs) hold great potential for clinical reasoning, their high computational and memory requirements…

Computers and Society · Computer Science 2026-05-12 Xinchun Su , Chunxu Luo , Lipeng Ma , Yixuan Li , Weidong Yang

Competency modeling is widely used in human resource management to select, develop, and evaluate talent. However, traditional expert-driven approaches rely heavily on manual analysis of large volumes of interview transcripts, making them…

Computation and Language · Computer Science 2026-02-16 Silin Du , Manqing Xin , Raymond Jia Wang

Large Language Models (LLMs) are versatile and demonstrate impressive generalization ability by mining and learning information from extensive unlabeled text. However, they still exhibit reasoning mistakes, often stemming from knowledge…

Computation and Language · Computer Science 2024-08-22 Kai Xiong , Xiao Ding , Li Du , Jiahao Ying , Ting Liu , Bing Qin , Yixin Cao

The rapid evolution of artificial intelligence in drug discovery encounters challenges with generalization and extensive training, yet Large Language Models (LLMs) offer promise in reshaping interactions with complex molecular data. Our…

Biomolecules · Quantitative Biology 2024-12-20 He Cao , Zijing Liu , Xingyu Lu , Yuan Yao , Yu Li

This paper argues that large language model-based recommenders can displace today's attention-allocation machinery. LLM-based recommenders would ingest open-web content, infer a user's natural-language goals, and present information that…

Computers and Society · Computer Science 2025-07-03 Seth Lazar , Luke Thorburn , Tian Jin , Luca Belli

Large language models (LLMs) have grown in their usage to provide support for question answering across numerous disciplines. The models on their own have already shown promise for answering basic questions, however fail quickly where…

Information Retrieval · Computer Science 2025-04-15 David Brett , Anniek Myatt

Based on official estimates, 50 million people worldwide are affected by dementia, and this number increases by 10 million new patients every year. Without a cure, clinical prognostication and early intervention represent the most effective…

Computation and Language · Computer Science 2024-09-06 Francisco de Arriba-Pérez , Silvia García-Méndez

Recommender systems are widely used in online services, with embedding-based models being particularly popular due to their expressiveness in representing complex signals. However, these models often function as a black box, making them…

Information Retrieval · Computer Science 2024-06-25 Yuxuan Lei , Jianxun Lian , Jing Yao , Xu Huang , Defu Lian , Xing Xie

Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

Computation and Language · Computer Science 2023-09-08 Supun Manathunga , Isuru Hettigoda

Large Language Models (LLMs) have demonstrated exceptional proficiency in text understanding and embedding tasks. However, their potential in multimodal representation, particularly for item-to-item (I2I) recommendations, remains…

Information Retrieval · Computer Science 2025-01-22 Chao Zhang , Haoxin Zhang , Shiwei Wu , Di Wu , Tong Xu , Xiangyu Zhao , Yan Gao , Yao Hu , Enhong Chen

The advent of Large Language Models (LLMs) heralds a pivotal shift in online user interactions with information. Traditional Information Retrieval (IR) systems primarily relied on query-document matching, whereas LLMs excel in comprehending…

Information Retrieval · Computer Science 2023-11-22 Samira Ghodratnama , Mehrdad Zakershahrak

Large Language Models (LLMs) have recently demonstrated impressive capabilities across various real-world applications. However, due to the current text-in-text-out paradigm, it remains challenging for LLMs to handle dynamic and complex…

Artificial Intelligence · Computer Science 2024-10-25 Timothy Wei , Annabelle Miin , Anastasia Miin

Addressing the complexity of accurately classifying International Classification of Diseases (ICD) codes from medical discharge summaries is challenging due to the intricate nature of medical documentation. This paper explores the use of…

Machine Learning · Computer Science 2024-11-12 Zeyd Boukhers , AmeerAli Khan , Qusai Ramadan , Cong Yang

Artificial intelligence (AI) technology has advanced rapidly in recent years, with large language models (LLMs) emerging as a significant breakthrough. LLMs are increasingly making an impact across various industries, with the medical field…

Artificial Intelligence · Computer Science 2025-09-24 Zhiyu Kan , Wensheng Gan , Zhenlian Qi , Philip S. Yu