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The recent surge in Multimodal Large Language Models (MLLMs) has showcased their remarkable potential for achieving generalized intelligence by integrating visual understanding into Large Language Models.Nevertheless, the sheer model size…

Computation and Language · Computer Science 2024-07-30 Shilin Xu , Xiangtai Li , Haobo Yuan , Lu Qi , Yunhai Tong , Ming-Hsuan Yang

The emergence of Large Language Models (LLMs) has achieved tremendous success in the field of Natural Language Processing owing to diverse training paradigms that empower LLMs to effectively capture intricate linguistic patterns and…

Information Retrieval · Computer Science 2024-07-04 Lemei Zhang , Peng Liu , Yashar Deldjoo , Yong Zheng , Jon Atle Gulla

The integration of Large Language Models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating drug discovery, and optimizing…

Quantitative Methods · Quantitative Biology 2024-09-10 Yizhen Zheng , Huan Yee Koh , Maddie Yang , Li Li , Lauren T. May , Geoffrey I. Webb , Shirui Pan , George Church

The rapid advancement of large language models (LLMs) has opened new boundaries in the extraction and synthesis of medical knowledge, particularly within evidence synthesis. This paper reviews the state-of-the-art applications of LLMs in…

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

Intelligent drug recommendation based on Electronic Health Records (EHRs) is critical for improving the quality and efficiency of clinical decision-making. By leveraging large-scale patient data, drug recommendation systems can assist…

Computation and Language · Computer Science 2025-12-08 Juntao Li , Haobin Yuan , Ling Luo , Yan Jiang , Fan Wang , Ping Zhang , Huiyi Lv , Jian Wang , Yuanyuan Sun , Hongfei Lin

Large language models (LLMs), such as GPT-4, have demonstrated remarkable capabilities across a wide range of tasks, including health applications. In this paper, we study how LLMs can be used to scale biomedical knowledge curation. We find…

Large Language Models (LLMs) have displayed remarkable performances across various complex tasks by leveraging Chain-of-Thought (CoT) prompting. Recently, studies have proposed a Knowledge Distillation (KD) approach, reasoning distillation,…

Computation and Language · Computer Science 2024-10-14 Hojae Lee , Junho Kim , SangKeun Lee

Multimodal recommender systems (MRS) integrate heterogeneous user and item data, such as text, images, and structured information, to enhance recommendation performance. The emergence of large language models (LLMs) introduces new…

Information Retrieval · Computer Science 2025-05-16 Alejo Lopez-Avila , Jinhua Du

We propose DISC-MedLLM, a comprehensive solution that leverages Large Language Models (LLMs) to provide accurate and truthful medical response in end-to-end conversational healthcare services. To construct high-quality Supervised…

Computation and Language · Computer Science 2023-08-29 Zhijie Bao , Wei Chen , Shengze Xiao , Kuang Ren , Jiaao Wu , Cheng Zhong , Jiajie Peng , Xuanjing Huang , Zhongyu Wei

Large Language Models (LLMs) have showcased exceptional capabilities in various domains, attracting significant interest from both academia and industry. Despite their impressive performance, the substantial size and computational demands…

Computation and Language · Computer Science 2024-07-03 Chuanpeng Yang , Wang Lu , Yao Zhu , Yidong Wang , Qian Chen , Chenlong Gao , Bingjie Yan , Yiqiang Chen

Recent advancements in recommendation systems have shifted towards more comprehensive and personalized recommendations by utilizing large language models (LLM). However, effectively integrating LLM's commonsense knowledge and reasoning…

Information Retrieval · Computer Science 2023-08-22 Zhixuan Chu , Hongyan Hao , Xin Ouyang , Simeng Wang , Yan Wang , Yue Shen , Jinjie Gu , Qing Cui , Longfei Li , Siqiao Xue , James Y Zhang , Sheng Li

The introduction of large language models (LLMs) has greatly enhanced the capabilities of software agents. Instead of relying on rule-based interactions, agents can now interact in flexible ways akin to humans. However, this flexibility…

Human-Computer Interaction · Computer Science 2026-02-04 Joar Sabel , Mattias Wingren , Andreas Lundell , Sören Andersson , Sara Rosenberg , Susanne Hägglund , Linda Estman , Malin Andtfolk

Sequential recommendation systems aim to predict users' next likely interaction based on their history. However, these systems face data sparsity and cold-start problems. Utilizing data from other domains, known as multi-domain methods, is…

Information Retrieval · Computer Science 2025-02-20 Zuoli Tang , Zhaoxin Huan , Zihao Li , Xiaolu Zhang , Jun Hu , Chilin Fu , Jun Zhou , Lixin Zou , Chenliang Li

Large language models (LLMs) have demonstrated remarkable performance across a wide range of industrial applications, from search and recommendation systems to generative tasks. Although scaling laws indicate that larger models generally…

Recent advancements in artificial intelligence (AI), especially large language models (LLMs), have significantly advanced healthcare applications and demonstrated potentials in intelligent medical treatment. However, there are conspicuous…

Computation and Language · Computer Science 2025-05-26 Qinkai Yu , Mingyu Jin , Dong Shu , Chong Zhang , Lizhou Fan , Wenyue Hua , Suiyuan Zhu , Yanda Meng , Zhenting Wang , Mengnan Du , Yongfeng Zhang

Large language models (LLMs) have achieved remarkable progress in the field of natural language processing (NLP), demonstrating remarkable abilities in producing text that resembles human language for various tasks. This opens up new…

Information Retrieval · Computer Science 2024-06-05 Jianghao Lin , Xinyi Dai , Rong Shan , Bo Chen , Ruiming Tang , Yong Yu , Weinan Zhang

In practice, clinicians achieve a diagnosis by following a sequence of steps, such as laboratory exams, observations, or imaging. The pathways to reach diagnosis decisions are documented by guidelines authored by expert organizations, which…

Computation and Language · Computer Science 2024-09-25 Elisa Castagnari , Lillian Muyama , Adrien Coulet

Molecule generation and optimization is a fundamental task in chemical domain. The rapid development of intelligent tools, especially large language models (LLMs) with powerful knowledge reserves and interactive capabilities, has provided…

Machine Learning · Computer Science 2026-02-10 Haoran Liu , Zheni Zeng , Yukun Yan , Yuxuan Chen , Yunduo Xiao

Ensuring the products displayed in e-commerce search results are relevant to users queries is crucial for improving the user experience. With their advanced semantic understanding, deep learning models have been widely used for relevance…

Information Retrieval · Computer Science 2025-05-13 Hongwei Shang , Nguyen Vo , Nitin Yadav , Tian Zhang , Ajit Puthenputhussery , Xunfan Cai , Shuyi Chen , Prijith Chandran , Changsung Kang