Related papers: Proton-CAT: a Novel Strategy for Enhanced Proton T…
Purpose: LATTICE, a form of spatially fractionated radiation therapy that delivers high-dose peaks and low-dose valleys within the target, has been clinically utilized for treating bulky tumors. However, its application to…
The interplay between the beam delivery time structure and the patient motion makes 4D dose calculation (4DDC) important when treating moving tumors with intensity modulated proton therapy. 4DDC based on phase sorting of a 4DCT suffers from…
Carbon ion is the mostly common used particle in heavy ion radiotherapy. In this paper, carbon ion dose in tumor treatment for human eye was simulated with FLUKA code, 80 MeV/u carbon beam was irradiated into the human eye from two…
In carbon-therapy, the interaction of the incoming beam with human tissues may lead to the production of a large amount of nuclear fragments and secondary light particles. An accurate estimation of the biological dose deposited into the…
To expedite the commissioning process of the proton therapy system at Samsung Medical Center (SMC), we have developed a Monte Carlo simulation model of the proton therapy nozzles using TOPAS. At SMC proton therapy center, we have two gantry…
A scheme with gold cone-capillary is proposed to improve the protons acceleration and involved problems are investigated by using the two-dimensional particle-in-cell simulations. It is demonstrated that the cone-capillary can efficiently…
Chemical substitution during growth is a well-established method to manipulate electronic states of quantum materials, and leads to rich spectra of phase diagrams in cuprate and iron-based superconductors. Here we report a novel and generic…
Background: Promising results for mammary carcinoma treatment with photodynamic therapy (PDT) presuppose a careful selection of irradiation light wavelength. Methods: 4T1 tumors implanted in NOD-SCID mice were treated with Metvix-PDT under…
Laser-accelerated protons have a great potential for innovative experiments in radiation biology due to the sub-picosecond pulse duration and high dose rate achievable. However, the broad angular divergence makes them not optimal for…
The long-term efficacy of targeted therapeutics for cancer treatment can be significantly limited by the type of therapy and development of drug resistance, inter alia. Experimental studies indicate that the factors enhancing acquisition of…
Particle therapy is an established method to treat deep-seated tumours using accelerator-produced ion beams. For treatment planning, the precise knowledge of the relative stopping power (RSP) within the patient is vital. Conversion errors…
Background : Proton flash therapy is an emergency research topic in radiation therapy since the Varian announced the promising results from the first in human clinical trial of Flash therapy recently. However, it still needs a lot of…
Renormalization of proton-proton fusion is studied in the framework of chiral effective field theory. Strict perturbative treatment of subleading corrections is applied in the analysis. Possible enhancement of two-nucleon contact axial…
Intensity modulated proton therapy (IMPT) provides highly conformal dose distributions through the application of multiple, angularly spaced fields, each applying an ad-hoc pattern of spatially varying particle fluences. In particular,…
Photocatalytic nitrogen fixation is an important pathway for carbon neutralization and sustainable development. Inspired by nitrogenase, the participation of molybdenum can effectively activate nitrogen. A novel Ti/Mo composites…
We investigate the target normal sheath acceleration of protons in thin aluminum targets irradiated at relativistic intensity by two time-separated ultrashort (35 fs) laser pulses. For identical laser pulses and target thicknesses of 3 and…
Accurate dose calculation is vitally important for proton therapy. Pencil beam (PB) model-based dose calculation is fast but inaccurate due to the approximation when dealing with inhomogeneities. Monte Carlo (MC) dose calculation is the…
Proton therapy exploits the finite range of charged particles in tissue to achieve dose distributions no photon based modality can replicate. Yet the modality reaches fewer than 1 percent of patients who might benefit a gap rooted in cost…
Purpose: In treatment planning of charged-particle radiotherapy, patient heterogeneity is conventionally modeled as variable-density water converted from CT images to best reproduce the stopping power, which may lead to inaccuracies in the…
Recent developments for the delivery of proton and ion beam therapy have been significant, and a number of technological solutions now exist for the creation and utilisation of these particles for the treatment of cancer. In this paper we…