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A model of an organism as an autonomous intelligent system has been proposed. This model was used to analyze learning of an organism in various environmental conditions. Processes of learning were divided into two types: strong and weak…

Artificial Intelligence · Computer Science 2007-05-23 Alexey V. Melkikh

We numerically demonstrate a network of coupled oscillators that can learn to solve a classification task from a set of examples -- performing both training and inference through the nonlinear evolution of the system. We accomplish this by…

Mesoscale and Nanoscale Physics · Physics 2026-01-07 Daan de Bos , Marc Serra-Garcia

Living organisms rely on molecular networks, such as gene circuits and signaling pathways, for information processing and robust decision-making in crowded, noisy environments. Recent advances show that interacting biomolecules…

Living organisms are molecular systems with self-sustained dynamics via energy conversion through molecular cooperation, resulting in highly complex macroscopic behaviors. Construction of such autonomous macroscopic dynamics at a molecular…

Physarum Polycephalum is a unicellular slime mold that has been intensely studied due to its ability to solve mazes, find shortest paths, generate Steiner trees, share knowledge, remember past events, and its applications to unconventional…

Biological Physics · Physics 2022-10-18 Sheryl Hsu , Laura P. Schaposnik

The hippocampus and the striatum support episodic and procedural memory, respectively, and "place" and "response" learning within spatial navigation. Recently this dichotomy has been linked to "model-based" and "model-free" reinforcement…

Neurons and Cognition · Quantitative Biology 2018-02-05 Chersi Fabian , Burgess Neil

Molecular simulations and biophysical experiments can be used to provide independent and complementary insights into the molecular origin of biological processes. A particularly useful strategy is to use molecular simulations as a modelling…

Chemical Physics · Physics 2019-12-10 Simone Orioli , Andreas Haahr Larsen , Sandro Bottaro , Kresten Lindorff-Larsen

Computer simulations have become an important tool across the biomedical sciences and beyond. For many important problems several different models or hypotheses exist and choosing which one best describes reality or observed data is not…

Quantitative Methods · Quantitative Biology 2010-01-20 Tina Toni , Michael P. H. Stumpf

The present habilitation thesis in theoretical biological physics addresses two central dynamical processes in cells and organisms: (i) active motility and motility control and (ii) self-organized pattern formation. The unifying theme is…

Cell Behavior · Quantitative Biology 2018-03-21 Benjamin M. Friedrich

Recent advances at the intersection of control theory, neuroscience, and machine learning have revealed novel mechanisms by which dynamical systems perform computation. These advances encompass a wide range of conceptual, mathematical, and…

Machine Learning · Computer Science 2026-04-10 Arthur N. Montanari , Francesco Bullo , Dmitry Krotov , Adilson E. Motter

Human cognition emerges from coordinated spiking dynamics in distributed neural circuits, where information is encoded via both firing rates and precise spike timing determined by brain rhythms. Inspired by this notion, we propose a…

Neurons and Cognition · Quantitative Biology 2026-05-05 Tingting Dan , Guorong Wu

The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…

Neurons and Cognition · Quantitative Biology 2020-12-02 Hui Wei

Living systems, from single cells to higher vertebrates, receive a continuous stream of non-stationary inputs that they sense, e.g., via cell surface receptors or sensory organs. Integrating these time-varying, multi-sensory, and often…

Other Quantitative Biology · Quantitative Biology 2024-04-17 Daniel Koch , Akhilesh Nandan , Gayathri Ramesan , Aneta Koseska

High auditory sensitivity, sharp frequency selectivity, and otoacoustic emissions are signatures of active amplification of the cochlea. The human ear can also detect very large amplitude sound without being damaged as long as the exposed…

Biological Physics · Physics 2008-10-01 Yong Zhang , Chul Koo Kim , Kong-Ju-Bock Lee , Youngah Park

We present a multi-scale differentiable brain modeling workflow utilizing BrainPy, a unique differentiable brain simulator that combines accurate brain simulation with powerful gradient-based optimization. We leverage this capability of…

Neural and Evolutionary Computing · Computer Science 2024-09-26 Chaoming Wang , Muyang Lyu , Tianqiu Zhang , Sichao He , Si Wu

Working memory is responsible for the temporary manipulation and storage of information to support reasoning, learning and comprehension in the human brain. Background oscillations from subcortical structures may drive a gating or switching…

Neurons and Cognition · Quantitative Biology 2016-01-29 Utku Çelikok , Eva M. Navarro-López , Neslihan S. Şengör

Humans and other organisms make decisions choosing between different options, with the aim to maximize the reward and minimize the cost. The main theoretical framework for modeling the decision-making process has been based on the highly…

Neurons and Cognition · Quantitative Biology 2024-11-19 Olga Tapinova , Tal Finkelman , Tamar Reitich-Stolero , Rony Paz , Assaf Tal , Nir S. Gov

Recent experiments have shown that the spontaneous activity of young dissociated neuronal cultures can be described as a process of highly inhomogeneous nucleation and front propagation due to the localization of noise activity, i.e., noise…

Neurons and Cognition · Quantitative Biology 2021-05-26 Javier G. Orlandi , Jaume Casademunt

A parallel program together with the parallel hardware it is running on is not only a vehicle to solve numerical problems, it is also a complex system with interesting dynamical behavior: resynchronization and desynchronization of parallel…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-11-15 Ayesha Afzal , Georg Hager , Gerhard Wellein

Plants are capable of intelligent responses to complex environmental signals. Learning and memory play fundamental roles in such responses. Two simple models of plant memory are proposed based on the calcium-signalling system. The memory…

Condensed Matter · Physics 2009-11-10 Indrani Bose , Rajesh Karmakar