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We propose a computationally and statistically efficient procedure for segmenting univariate data under piecewise linearity. The proposed moving sum (MOSUM) methodology detects multiple change points where the underlying signal undergoes…

Methodology · Statistics 2023-08-25 Joonpyo Kim , Hee-Seok Oh , Haeran Cho

The research described herewith investigates detecting change points of means and of variances in a sequence of observations. The number of change points can be divergent at certain rate as the sample size goes to infinity. We define a…

Methodology · Statistics 2020-03-04 Wenbiao Zhao , Xuehu Zhu , Lixing Zhu

Change point detection plays a fundamental role in many real-world applications, where the goal is to analyze and monitor the behaviour of a data stream. In this paper, we study change detection in binary streams. To this end, we use a…

Machine Learning · Computer Science 2023-01-24 Nikolaj Tatti

Cell crawling is critical to biological development, homeostasis and disease. In many cases, cell trajectories are quasi-random-walk. In vitro assays on flat surfaces often described such quasi-random-walk cell trajectories as…

Change point detection in covariance structures is a fundamental and crucial problem for sequential data. Under the high-dimensional setting, most of the existing research has focused on identifying change points in historical data.…

Statistics Theory · Mathematics 2026-02-02 Zhigang Bao , Kha Man Cheong , Yuji Li , Jiaxin Qiu

This paper is concerned with the estimation of time-varying networks for high-dimensional nonstationary time series. Two types of dynamic behaviors are considered: structural breaks (i.e., abrupt change points) and smooth changes. To…

Statistics Theory · Mathematics 2020-02-19 Mengyu Xu , Xiaohui Chen , Wei Biao Wu

The movement of intracellular cargo transported by molecular motors is commonly marked by switches between directed motion and stationary pauses. The predominant measure for assessing movement is effective diffusivity, which predicts the…

Quantitative Methods · Quantitative Biology 2024-12-31 Keisha J. Cook , Nathan Rayens , Linh Do , Christine K. Payne , Scott A. McKinley

Mathematical models are vital interpretive and predictive tools used to assist in the understanding of cell migration. There are typically two approaches to modelling cell migration: either micro-scale, discrete or macro-scale, continuum.…

Cell Behavior · Quantitative Biology 2018-08-16 Enrico Gavagnin , Christian A. Yates

Conventional cell tracking methods detect multiple cells in each frame (detection) and then associate the detection results in successive time-frames (association). Most cell tracking methods perform the association task independently from…

Computer Vision and Pattern Recognition · Computer Science 2020-02-27 Junya Hayashida , Kazuya Nishimura , Ryoma Bise

Stereotyped behaviors are series of postures that show very little variability between repeats. They have been used to classify the dynamics of individuals, groups and species without reference to the lower-level mechanisms that drive them.…

Cell Behavior · Quantitative Biology 2019-06-12 Luke Tweedy , Patrick Witzel , Doris Heinrich , Robert H. Insall , Robert G. Endres

Single-cell trajectory analysis aims to reconstruct the biological developmental processes of cells as they evolve over time, leveraging temporal correlations in gene expression. During cellular development, gene expression patterns…

Applications · Statistics 2026-03-30 Junhao Zhu , Kevin Zhang , Zhaolei Zhang , Dehan Kong

It is increasingly the case with modern time series that many data sets of practical interest contain abrupt changes in structure. These changes may occur in complex characteristics such as the extremal dependence structure, and identifying…

Methodology · Statistics 2025-09-03 Euan T. McGonigle , Matthew Pawley , Jordan Richards , Christian Rohrbeck

The ocean is filled with phytoplankton that contribute as much photosynthesis as all land plants combined, making them vital to the carbon cycle and climate system. Recent advances in flow cytometry allow oceanographers to measure the…

Methodology · Statistics 2026-03-09 Yik Lun Kei , Qi Wang , Paul Parker , Francois Ribalet , Sangwon Hyun

The segmentation of data into stationary stretches also known as multiple change point problem is important for many applications in time series analysis as well as signal processing. Based on strong invariance principles, we analyse data…

Methodology · Statistics 2023-11-17 Claudia Kirch , Philipp Klein

The dynamics of single cell migration on flat surfaces is usually modeled by a Langevin-like problem consisting of ballistic motion for short periods and random walk. for long periods. Conversely, recent studies have revealed a previously…

A method for change point detection is proposed. We consider a univariate sequence of independent random variables with piecewise constant expectation and variance, apart from which the distribution may vary periodically. We aim to detect…

Methodology · Statistics 2021-06-23 Michael Messer

This paper studies methods for testing and estimating change-points in the covariance structure of a high-dimensional linear time series. The assumed framework allows for a large class of multivariate linear processes (including vector…

Statistics Theory · Mathematics 2020-01-14 Ansgar Steland

We investigate path-wise observables in experiments on driven colloids in a periodic light field to dissect selected intricate transport features, kinetics, and transition-path time statistics out of thermodynamic equilibrium. These…

In Change point detection task Likelihood Ratio Test (LRT) is sequentially applied in a sliding window procedure. Its high values indicate changes of parametric distribution in the data sequence. Correspondingly LRT values require…

Statistics Theory · Mathematics 2017-10-23 Nazar Buzun , Valeriy Avanesov

In this work, we introduce CPLASS (Continuous Piecewise-Linear Approximation via Stochastic Search), an algorithm for detecting changes in velocity within multidimensional data. The one-dimensional version of this problem is known as the…

Methodology · Statistics 2026-01-15 Linh Do , Dat Do , Keisha J. Cook , Scott A. McKinley
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