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Carcinogenesis is a proteiform phenomenon, with tumors emerging in various locations and displaying complex, diverse shapes. At the crucial intersection of research and clinical practice, it demands precise and flexible assessment. However,…

Human readers or radiologists routinely perform full-body multi-organ multi-disease detection and diagnosis in clinical practice, while most medical AI systems are built to focus on single organs with a narrow list of a few diseases. This…

Trustworthy clinical advice is crucial but burdensome when seeking health support from professionals. Inaccessibility and financial burdens present obstacles to obtaining professional clinical advice, even when healthcare is available.…

Human-Computer Interaction · Computer Science 2024-02-14 Delong Du , Richard Paluch , Gunnar Stevens , Claudia Müller

Campus climate surveys play a pivotal role in capturing how students, faculty, and staff experience university life, yet traditional methods frequently suffer from low participation and minimal follow-up. We present TigerGPT, a new AI…

Human-Computer Interaction · Computer Science 2025-04-22 Jinwen Tang , Songxi Chen , Yi Shang

Biological systems are governed by structured molecular interactions, where pathways, regulatory circuits, and functional gene relationships shape cellular behavior and disease progression. Much of this knowledge is naturally represented as…

Machine Learning · Computer Science 2026-05-26 Yuwei Xue , Sakib Mostafa , James Zou , Joseph Liao , Maximilian Diehn , Ash A. Alizadeh , Lei Xing , Md. Tauhidul Islam

Objective: Assess the feasibility of using ChatGPT or a similar AI-based chatbot for patient-provider communication. Participants: A US representative sample of 430 study participants aged 18 and above. 53.2% of respondents analyzed were…

Human-Computer Interaction · Computer Science 2023-01-25 Oded Nov , Nina Singh , Devin Mann

Purpose: Thyroid cancer has been a common cancer. Papillary thyroid cancer and follicular thyroid cancer are the two most common types of thyroid cancer. Follicular thyroid cancer lacks distinctive ultrasound signs and is more difficult to…

Machine Learning · Computer Science 2025-09-17 Songlin Zhou , Tao Zhou , Xin Li , Stephen Shing-Toung Yau

Purpose of review: Artificial intelligence (AI) has become popular in medical applications, specifically as a clinical support tool for computer-aided diagnosis. These tools are typically employed on medical data (i.e., image, molecular…

Machine Learning · Computer Science 2022-06-08 Ahmad Chaddad , Yousef Katib , Lama Hassan

Over the past decades, the incidence of thyroid cancer has been increasing globally. Accurate and early diagnosis allows timely treatment and helps to avoid over-diagnosis. Clinically, a nodule is commonly evaluated from both transverse and…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Han Huang , Yijie Dong , Xiaohong Jia , Jianqiao Zhou , Dong Ni , Jun Cheng , Ruobing Huang

[18F]FDG-PET/CT is a cornerstone imaging modality for tumor staging and treatment response assessment across many cancer types, yet expert reader shortages necessitate more efficient diagnostic aids. While standalone AI models for automatic…

Background We aim to use Natural Language Processing (NLP) to automate the extraction and classification of thyroid cancer risk factors from pathology reports. Methods We analyzed 1,410 surgical pathology reports from adult papillary…

Generalist Medical AI (GMAI) systems have demonstrated expert-level performance in biomedical perception tasks, yet their clinical utility remains limited by inadequate multi-modal explainability and suboptimal prognostic capabilities.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Honglong Yang , Shanshan Song , Yi Qin , Lehan Wang , Haonan Wang , Xinpeng Ding , Qixiang Zhang , Bodong Du , Xiaomeng Li

The release of ChatGPT, a language model capable of generating text that appears human-like and authentic, has gained significant attention beyond the research community. We expect that the convincing performance of ChatGPT incentivizes…

Computer-aided diagnosis systems hold great promise to aid radiologists and clinicians in radiological clinical practice and enhance diagnostic accuracy and efficiency. However, the conventional systems primarily focus on delivering…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Sheng Wang , Tianming Du , Katherine Fischer , Gregory E Tasian , Justin Ziemba , Joanie M Garratt , Hersh Sagreiya , Yong Fan

The large language model called ChatGPT has drawn extensively attention because of its human-like expression and reasoning abilities. In this study, we investigate the feasibility of using ChatGPT in experiments on using ChatGPT to…

Computation and Language · Computer Science 2024-10-22 Qing Lyu , Josh Tan , Michael E. Zapadka , Janardhana Ponnatapura , Chuang Niu , Kyle J. Myers , Ge Wang , Christopher T. Whitlow

Ultrasound is a useful technique for diagnosing thyroid nodules. Benign and malignant nodules that automatically discriminate in the ultrasound pictures can provide diagnostic recommendations or, improve diagnostic accuracy in the absence…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Ponugoti Nikhila , Sabari Nathan , Elmer Jeto Gomes Ataide , Alfredo Illanes , Michael Friebe , Srichandana Abbineni

As AI chatbots gain adoption in clinical medicine, developing effective frameworks for complex, emerging diseases presents significant challenges. We developed and evaluated six Retrieval-Augmented Generation (RAG) corpus configurations for…

Artificial Intelligence · Computer Science 2025-10-20 Philip DiGiacomo , Haoyang Wang , Jinrui Fang , Yan Leng , W Michael Brode , Ying Ding

Diagnosing rare diseases presents a common challenge in clinical practice, necessitating the expertise of specialists for accurate identification. The advent of machine learning offers a promising solution, while the development of such…

Machine Learning · Computer Science 2024-03-12 Yifan Wu , Yang Liu , Yue Yang , Michael S. Yao , Wenli Yang , Xuehui Shi , Lihong Yang , Dongjun Li , Yueming Liu , James C. Gee , Xuan Yang , Wenbin Wei , Shi Gu

Vision-language models (VLM) have markedly advanced AI-driven interpretation and reporting of complex medical imaging, such as computed tomography (CT). Yet, existing methods largely relegate clinicians to passive observers of final…

Recently, intelligent analysis of lung nodules with the assistant of computer aided detection (CAD) techniques can improve the accuracy rate of lung cancer diagnosis. However, existing CAD systems and pulmonary datasets mainly focus on…

Image and Video Processing · Electrical Eng. & Systems 2024-06-27 Muwei Jian , Haoran Zhang , Mingju Shao , Hongyu Chen , Huihui Huang , Yanjie Zhong , Changlei Zhang , Bin Wang , Penghui Gao