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Connected operators are filtering tools that act by merging elementary regions of an image. A popular strategy is based on tree-based image representations: for example, one can compute an attribute on each node of the tree and keep only…

Computer Vision and Pattern Recognition · Computer Science 2012-07-17 Yongchao Xu , Thierry Géraud , Laurent Najman

Multiplexed immunofluorescence provides an unprecedented opportunity for studying specific cell-to-cell and cell microenvironment interactions. We employ graph neural networks to combine features obtained from tissue morphology with…

Collecting pixel-level labels for medical datasets can be a laborious and expensive process, and enhancing segmentation performance with a scarcity of labeled data is a crucial challenge. This work introduces AugPaint, a data augmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Xinrong Hu , Yiyu Shi

Comprehensive assessment of the various aspects of the brain's microstructure requires the use of complementary imaging techniques. This includes measuring the spatial distribution of cell bodies (cytoarchitecture) and nerve fibers…

Estimating slide- and patch-level gene expression profiles from pathology images enables rapid and low-cost molecular analysis with broad clinical impact. Despite strong results, existing approaches treat gene expression as a mere slide- or…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Kazuya Nishimura , Ryoma Bise , Shinnosuke Matsuo , Haruka Hirose , Yasuhiro Kojima

The distribution and appearance of nuclei are essential markers for the diagnosis and study of cancer. Despite the importance of nuclear morphology, there is a lack of large scale, accurate, publicly accessible nucleus segmentation data. To…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Le Hou , Rajarsi Gupta , John S. Van Arnam , Yuwei Zhang , Kaustubh Sivalenka , Dimitris Samaras , Tahsin M. Kurc , Joel H. Saltz

Inpainting-based image compression is a promising alternative to classical transform-based lossy codecs. Typically it stores a carefully selected subset of all pixel locations and their colour values. In the decoding phase the missing…

Image and Video Processing · Electrical Eng. & Systems 2023-05-16 Ferdinand Jost , Vassillen Chizhov , Joachim Weickert

Mathematical morphology is a theory and technique to collect features like geometric and topological structures in digital images. Given a target image, determining suitable morphological operations and structuring elements is a cumbersome…

Computer Vision and Pattern Recognition · Computer Science 2019-09-05 Yucong Shen , Xin Zhong , Frank Y. Shih

Multiplex Imaging (MI) enables the simultaneous visualization of multiple biological markers in separate imaging channels at subcellular resolution, providing valuable insights into cell-type heterogeneity and spatial organization. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-07 Simon Gutwein , Daria Lazic , Thomas Walter , Sabine Taschner-Mandl , Roxane Licandro

We propose a general framework for a collaborative machine learning system to assist bioscience researchers with the task of labeling specific cell identities from microscopic still or video imaging. The distinguishing features of this…

Quantitative Methods · Quantitative Biology 2019-03-25 Greg Bubnis , Steven Ban , Matthew D. DiFranco , Saul Kato

Face morphing is a problem in computer graphics with numerous artistic and forensic applications. It is challenging due to variations in pose, lighting, gender, and ethnicity. This task consists of a warping for feature alignment and a…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Guilherme Schardong , Tiago Novello , Hallison Paz , Iurii Medvedev , Vinícius da Silva , Luiz Velho , Nuno Gonçalves

The accurate segmentation and tracking of cells in microscopy image sequences is an important task in biomedical research, e.g., for studying the development of tissues, organs or entire organisms. However, the segmentation of touching…

Computer Vision and Pattern Recognition · Computer Science 2020-12-10 Tim Scherr , Katharina Löffler , Moritz Böhland , Ralf Mikut

Despite their black-box nature, deep learning models are extensively used in image-based drug discovery to extract feature vectors from single cells in microscopy images. To better understand how these networks perform representation…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Vivek Gopalakrishnan , Jingzhe Ma , Zhiyong Xie

The colorful appearance of a physical painting is determined by the distribution of paint pigments across the canvas, which we model as a per-pixel mixture of a small number of pigments with multispectral absorption and scattering…

Graphics · Computer Science 2018-07-23 Jianchao Tan , Stephen DiVerdi , Jingwan Lu , Yotam Gingold

Visualizing the details of different cellular structures is of great importance to elucidate cellular functions. However, it is challenging to obtain high quality images of different structures directly due to complex cellular environments.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-01 Yi Liu , Hao Yuan , Zhengyang Wang , Shuiwang Ji

The visual attributes of cells, such as the nuclear morphology and chromatin openness, are critical for histopathology image analysis. By learning cell-level visual representation, we can obtain a rich mix of features that are highly…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Bo Hu , Ye Tang , Eric I-Chao Chang , Yubo Fan , Maode Lai , Yan Xu

In this paper, we present a cosmetic-specific skin image dataset. It consists of skin images from $45$ patches ($5$ skin patches each from $9$ participants) of size $8mm^*8mm$ under three cosmetic products (i.e., foundation, blusher, and…

Computer Vision and Pattern Recognition · Computer Science 2024-01-12 Toby Chong , Alina Chadwick , I-chao Shen , Haoran Xie , Takeo Igarashi

Accurate cell counting is essential in various biomedical research and clinical applications, including cancer diagnosis, stem cell research, and immunology. Manual counting is labor-intensive and error-prone, motivating automation through…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Abdurahman Ali Mohammed , Catherine Fonder , Ying Wei , Wallapak Tavanapong , Donald S Sakaguchi , Qi Li , Surya K. Mallapragada

Background and objective: Prior probability shift between training and deployment datasets challenges deep learning-based medical image classification. Standard correction methods reweight posterior probabilities to adjust prior bias, yet…

Quantitative Methods · Quantitative Biology 2025-11-06 Takaaki Tachibana , Toru Nagasaka , Yukari Adachi , Hiroki Kagiyama , Ryota Ito , Mitsugu Fujita , Kimihiro Yamashita , Yoshihiro Kakeji

Label-free single-cell imaging offers a scalable, non-invasive alternative to fluorescence-based cytometry, yet inferring molecular phenotypes directly from bright-field morphology remains challenging. We present a unified Deep Learning…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Saqib Nazir , Ardhendu Behera