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It is currently accepted that cortical maps are dynamic constructions that are altered in response to external input. Experience-dependent structural changes in cortical microcurcuts lead to changes of activity, i.e. to changes in…

Neurons and Cognition · Quantitative Biology 2013-02-26 F. Gafarov , N. Khusnutdinov , F. Galimyanov

Higher brain function relies upon the ability to flexibly integrate information across specialized communities of brain regions, however it is unclear how this mechanism manifests over time. In this study, we use time-resolved network…

Causal relations among neuronal populations of the brain are studied through the so-called effective connectivity (EC) network. The latter is estimated from EEG or fMRI measurements, by inverting a generative model of the corresponding…

Systems and Control · Computer Science 2018-02-16 Giulia Prando , Mattia Zorzi , Alessandra Bertoldo , Alessandro Chiuso

Computational modeling and simulation have become essential tools in the quest to better understand the brain's makeup and to decipher the causal interrelations of its components. The breadth of biochemical and biophysical processes and…

Neurons and Cognition · Quantitative Biology 2019-06-10 Francesco Cremonesi , Felix Schürmann

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

The representation of the flow of information between neurons in the brain based on their activity is termed the causal functional connectome. Such representation incorporates the dynamic nature of neuronal activity and causal interactions…

Neurons and Cognition · Quantitative Biology 2022-11-16 Rahul Biswas , Eli Shlizerman

Active sensing is traditionally defined as the expenditure of energy, typically in the form of movement, for obtaining information. Here, we propose that the combination of reliance on adaptive sensors, the linkage between movement and…

Neurons and Cognition · Quantitative Biology 2026-05-25 Andrew Lamperski , Debojyoti Biswas , Eric S. Fortune , John Guckenheimer , Kathleen Hoffman , Noah J. Cowan

Neural circuits comprise multiple interconnected regions, each with complex dynamics. The interplay between local and global activity is thought to underlie computational flexibility, yet the structure of multiregion neural activity and its…

Neurons and Cognition · Quantitative Biology 2025-01-09 David G. Clark , Manuel Beiran

Dimensionality reduction, a form of compression, can simplify representations of information to increase efficiency and reveal general patterns. Yet, this simplification also forfeits information, thereby reducing representational capacity.…

A central goal in neuroscience is to provide explanations for how animal nervous systems can generate actions and cognitive states such as consciousness while artificial intelligence (AI) and machine learning (ML) seek to provide models…

Neurons and Cognition · Quantitative Biology 2024-05-24 Catalin C. Mitelut

In this review, we describe the singular success of attractor neural network models in describing how the brain maintains persistent activity states for working memory, error-corrects, and integrates noisy cues. We consider the mechanisms…

Neurons and Cognition · Quantitative Biology 2022-03-03 Mikail Khona , Ila R. Fiete

*Concept-based explanations* offer a promising approach for explaining the predictions of deep neural networks in terms of high-level, human-understandable concepts. However, existing methods either do not establish a causal connection…

Machine Learning · Computer Science 2026-05-08 Ronaldo Canizales , Divya Gopinath , Corina Păsăreanu , Ravi Mangal

A number of studies have concluded that dreaming is mostly caused by randomly arriving internal signals because "dream contents are random impulses", and argued that dream sleep is unlikely to play an important part in our intellectual…

Neurons and Cognition · Quantitative Biology 2026-02-05 Qi Zhang

The ability to modulate brain states using targeted stimulation is increasingly being employed to treat neurological disorders and to enhance human performance. Despite the growing interest in brain stimulation as a form of neuromodulation,…

Neurons and Cognition · Quantitative Biology 2016-01-07 Sarah Feldt Muldoon , Fabio Pasqualetti , Shi Gu , Matthew Cieslak , Scott T. Grafton , Jean M. Vettel , Danielle S. Bassett

Functional connections in the brain are frequently represented by weighted networks, with nodes representing locations in the brain, and edges representing the strength of connectivity between these locations. One challenge in analyzing…

Applications · Statistics 2022-09-28 Yura Kim , Daniel Kessler , Elizaveta Levina

Human brain dynamics can be profitably viewed through the lens of statistical mechanics, where neurophysiological activity evolves around and between local attractors representing preferred mental states. Many physically-inspired models of…

Neurons and Cognition · Quantitative Biology 2016-09-06 Arian Ashourvan , Shi Gu , Marcelo G. Mattar , Jean M. Vettel , Danielle S. Bassett

Computations related to learning processes within an organizational social network area require some network model preparation and specific algorithms in order to implement human behaviors in simulated environments. The proposals in this…

Computers and Society · Computer Science 2015-05-13 Przemyslaw Rozewski , Jaroslaw Jankowski , Piotr Brodka , Radoslaw Michalski

Cognitive effort, defined as the relationship between cognitive load and task performance, provides insight into how individuals allocate mental resources during demanding tasks. This construct is particularly important in high-stakes…

Human-Computer Interaction · Computer Science 2026-04-13 Shayla Sharmin , Mohammad Fahim Abrar , Gael Lucero-Palacios , Aditya Raikwar , Roghayeh Leila Barmaki

The ability of reasoning beyond data fitting is substantial to deep learning systems in order to make a leap forward towards artificial general intelligence. A lot of efforts have been made to model neural-based reasoning as an iterative…

Artificial Intelligence · Computer Science 2019-05-31 Xiaoran Xu , Wei Feng , Zhiqing Sun , Zhi-Hong Deng

Computational cognitive models discovered using large language models have so far relied solely on behavioral data. However, it is well-known that models produced from the behavioral trajectory alone are typically under-determined. In this…

Neurons and Cognition · Quantitative Biology 2026-05-07 Hanbo Xie , Akshay K. Jagadish , Lan Pan , Robert C. Wilson