English
Related papers

Related papers: GenFormer: A Deep-Learning-Based Approach for Gene…

200 papers

Diffusion models (DMs) represent state-of-the-art generative models for continuous inputs. DMs work by constructing a Stochastic Differential Equation (SDE) in the input space (ie, position space), and using a neural network to reverse it.…

Machine Learning · Computer Science 2024-05-14 Tianrong Chen , Jiatao Gu , Laurent Dinh , Evangelos A. Theodorou , Joshua Susskind , Shuangfei Zhai

This paper formed part of a preliminary research report for a risk consultancy and academic research. Stochastic Programming models provide a powerful paradigm for decision making under uncertainty. In these models the uncertainties are…

Computational Finance · Quantitative Finance 2009-04-08 Sovan Mitra

The Transformer model has shown strong performance in multivariate time series forecasting by leveraging channel-wise self-attention. However, this approach lacks temporal constraints when computing temporal features and does not utilize…

Machine Learning · Computer Science 2025-05-06 Shiwei Guo , Ziang Chen , Yupeng Ma , Yunfei Han , Yi Wang

We introduce a novel method to unite deep learning with biology by which generative adversarial networks (GANs) generate transcriptome perturbations and reveal condition-defining gene expression patterns. We find that a generator…

Quantitative Methods · Quantitative Biology 2019-07-02 Colin Targonski , Benjamin T. Shealy , Melissa C. Smith , F. Alex Feltus

This paper motivates the use of random-bridges -- stochastic processes conditioned to take target distributions at fixed timepoints -- in the realm of generative modelling. Herein, random-bridges can act as stochastic transports between two…

Machine Learning · Computer Science 2026-04-07 Stefano Goria , Levent A. Mengütürk , Murat C. Mengütürk , Berkan Sesen

Renewable energy projects, such as large offshore wind farms, are critical to achieving low-emission targets set by governments. Stochastic computer models allow us to explore future scenarios to aid decision making whilst considering the…

Methodology · Statistics 2021-12-07 Jack C. Kennedy , Daniel A. Henderson , Kevin J. Wilson

Time series forecasting plays a vital role across scientific, industrial, and environmental domains, especially when dealing with high-dimensional and nonlinear systems. While Transformer-based models have recently achieved state-of-the-art…

Machine Learning · Computer Science 2025-08-05 Ali Forootani , Mohammad Khosravi , Masoud Barati

We introduce a generative smoothness regularization on manifolds (SToRM) model for the recovery of dynamic image data from highly undersampled measurements. The model assumes that the images in the dataset are non-linear mappings of…

Image and Video Processing · Electrical Eng. & Systems 2021-03-12 Qing Zou , Abdul Haseeb Ahmed , Prashant Nagpal , Stanley Kruger , Mathews Jacob

Artificial Intelligence (AI) research often aims to develop models that can generalize reliably across complex datasets, yet this remains challenging in fields where data is scarce, intricate, or inaccessible. This paper introduces a novel…

Machine Learning · Computer Science 2024-12-20 Mohammad Zbeeb , Mohammad Ghorayeb , Mariam Salman

We investigate learning the eigenfunctions of evolution operators for time-reversal invariant stochastic processes, a prime example being the Langevin equation used in molecular dynamics. Many physical or chemical processes described by…

Machine Learning · Computer Science 2024-12-11 Timothée Devergne , Vladimir Kostic , Michele Parrinello , Massimiliano Pontil

We introduce SurgFormer, a multiresolution gated transformer for data driven soft tissue simulation on volumetric meshes. High fidelity biomechanical solvers are often too costly for interactive use, so we train SurgFormer on solver…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Ashkan Shahbazi , Elaheh Akbari , Kyvia Pereira , Jon S. Heiselman , Annie C. Benson , Garrison L. H. Johnston , Jie Ying Wu , Nabil Simaan , Michael I. Miga , Soheil Kolouri

Stochastic kinetic models describe systems across biology, chemistry, and physics where discrete events and small populations render deterministic approximations inadequate. Parameter inference and inverse design in these systems require…

Computational Physics · Physics 2026-03-06 Francesco Mottes , Qian-Ze Zhu , Michael P. Brenner

Generative models have recently emerged as powerful surrogates for physical systems, demonstrating increased accuracy, stability, and/or statistical fidelity. Most approaches rely on iteratively denoising a Gaussian, a choice that may not…

Machine Learning · Computer Science 2025-10-01 Anthony Zhou , Alexander Wikner , Amaury Lancelin , Pedram Hassanzadeh , Amir Barati Farimani

This paper studies the dynamic generator model for spatial-temporal processes such as dynamic textures and action sequences in video data. In this model, each time frame of the video sequence is generated by a generator model, which is a…

Machine Learning · Statistics 2018-12-31 Jianwen Xie , Ruiqi Gao , Zilong Zheng , Song-Chun Zhu , Ying Nian Wu

Path planning in complex environments is one of the key problems of artificial intelligence because it requires simultaneous understanding of the geometry of space and the global structure of the problem. In this paper, we explore the…

Artificial Intelligence · Computer Science 2026-02-24 Agnieszka Polowczyk , Alicja Polowczyk , Michał Wieczorek

Probabilistic inference in high-dimensional state-space models is computationally challenging. For many spatiotemporal systems, however, prior knowledge about the dependency structure of state variables is available. We leverage this…

Machine Learning · Computer Science 2024-08-09 Fiona Lippert , Bart Kranstauber , E. Emiel van Loon , Patrick Forré

Efficiently leveraging simulation to acquire advanced manipulation skills is both challenging and highly significant. We introduce \textit{ForeRobo}, a generative robotic agent that utilizes generative simulations to autonomously acquire…

Robotics · Computer Science 2025-11-07 Dexin wang , Faliang Chang , Chunsheng Liu

In this work we investigate approaches to reconstruct generator models from measurements available at the generator terminal bus using machine learning (ML) techniques. The goal is to develop an emulator which is trained online and is…

Machine Learning · Statistics 2021-09-15 Nikolay Stulov , Dejan J Sobajic , Yury Maximov , Deepjyoti Deka , Michael Chertkov

Generative models such as Large Language Models, Diffusion Models, and generative adversarial networks have recently revolutionized the creation of synthetic data, offering scalable solutions to data scarcity, privacy, and annotation…

Machine Learning · Computer Science 2025-08-28 Dawei Li , Yue Huang , Ming Li , Tianyi Zhou , Xiangliang Zhang , Huan Liu

Reconciling symbolic and distributed representations is a crucial challenge that can potentially resolve the limitations of current deep learning. Remarkable advances in this direction have been achieved recently via generative…

Machine Learning · Computer Science 2021-02-09 Jindong Jiang , Sungjin Ahn