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Cognitive decline is a natural part of aging. However, under some circumstances, this decline is more pronounced than expected, typically due to disorders such as Alzheimer's disease. Early detection of an anomalous decline is crucial, as…

Early detection of cognitive decline is crucial for enabling interventions that can slow neurodegenerative disease progression. Traditional diagnostic approaches rely on labor-intensive clinical assessments, which are impractical for…

Computation and Language · Computer Science 2025-09-04 Kristin Qi , Youxiang Zhu , Caroline Summerour , John A. Batsis , Xiaohui Liang

The global prevalence of dementia is projected to double by 2050, highlighting the urgent need for scalable diagnostic tools. This study utilizes digital cognitive tasks with eye-tracking data correlated with memory processes to distinguish…

Human-Computer Interaction · Computer Science 2025-08-28 Tomás Silva Santos Rocha , Anastasiia Mikhailova , Moreno I. Coco , José Santos-Victor

Co-channel interference cancellation (CCI) is the process used to reduce interference from other signals using the same frequency channel, thereby enhancing the performance of wireless communication systems. An improvement to this approach…

Signal Processing · Electrical Eng. & Systems 2024-11-20 Mostafa Naseri , Eli De Poorter , Ingrid Moerman , H. Vincent Poor , Adnan Shahid

The existing image manipulation localization (IML) models mainly relies on visual cues, but ignores the semantic logical relationships between content features. In fact, the content semantics conveyed by real images often conform to human…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Songlin Li , Zhiqing Guo , Yuanman Li , Zeyu Li , Yunfeng Diao , Gaobo Yang , Liejun Wang

Mild Cognitive Impairment (MCI) is an early stage of Alzheimer's disease (AD), a form of neurodegenerative disorder. Early identification of MCI is crucial for delaying its progression through timely interventions. Existing research has…

Audio and Speech Processing · Electrical Eng. & Systems 2024-10-18 Kristin Qi , Jiatong Shi , Caroline Summerour , John A. Batsis , Xiaohui Liang

Deep learning systems have been reported to achieve state-of-the-art performances in many applications, and a key is the existence of well trained classifiers on benchmark datasets. As a main-stream loss function, the cross entropy can…

Machine Learning · Computer Science 2022-09-22 Jirong Yi , Qiaosheng Zhang , Zhen Chen , Qiao Liu , Wei Shao

Natural language inference (NLI) is a central problem in language understanding. End-to-end artificial neural networks have reached state-of-the-art performance in NLI field recently. In this paper, we propose Character-level Intra…

Computation and Language · Computer Science 2017-07-25 Han Yang , Marta R. Costa-jussà , José A. R. Fonollosa

This study explores a multi-lingual audio self-supervised learning model for detecting mild cognitive impairment (MCI) using the TAUKADIAL cross-lingual dataset. While speech transcription-based detection with BERT models is effective,…

Audio and Speech Processing · Electrical Eng. & Systems 2025-01-28 Yueguan Wang , Tatsunari Matsushima , Soichiro Matsushima , Toshimitsu Sakai

Speech, language, and communication deficits are present in most neurodegenerative syndromes. They enable the early detection, diagnosis, treatment planning, and monitoring of neurocognitive disease progression as part of traditional…

Computation and Language · Computer Science 2023-12-07 Charalambos Themistocleous , Kyrana Tsapkini , Dimitrios Kokkinakis

Multiple sclerosis is an inflammatory autoimmune demyelinating disease that is characterized by lesions in the central nervous system. Typically, magnetic resonance imaging (MRI) is used for tracking disease progression. Automatic image…

Image and Video Processing · Electrical Eng. & Systems 2020-08-06 Nils Gessert , Julia Krüger , Roland Opfer , Ann-Christin Ostwaldt , Praveena Manogaran , Hagen H. Kitzler , Sven Schippling , Alexander Schlaefer

Although Large Language Models (LLMs) can generate coherent text, they often struggle to recognise user intent behind queries. In contrast, Natural Language Understanding (NLU) models interpret the purpose and key information of user input…

Computation and Language · Computer Science 2025-06-02 Yan Li , So-Eon Kim , Seong-Bae Park , Soyeon Caren Han

Traditional loss functions in medical image segmentation, such as Dice, often under-segment small lesions because their small relative volume contributes negligibly to the overall loss. To address this, instance-wise loss functions and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Luc Bouteille , Alexander Jaus , Jens Kleesiek , Rainer Stiefelhagen , Lukas Heine

An interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' interpretations. The dataset used comprises…

Increased variability in performance has been associated with the emergence of several neurological and psychiatric pathologies. However, whether and how consistency of neuronal activity may also be indicative of an underlying pathology is…

Neurons and Cognition · Quantitative Biology 2014-10-31 J. H. Martínez , J. M. Pastor , P. Ariza , M. Zanin , D. Papo , F. Maestú , R. Bajo , S. Boccaletti , J. M. Buldú

Understanding how individuals with Parkinson's disease (PD) describe cognitive experiences in their daily lives can offer valuable insights into disease-related cognitive and emotional changes. However, extracting such information from…

Computation and Language · Computer Science 2025-11-13 Varada Khanna , Nilay Bhatt , Ikgyu Shin , Sule Tinaz , Yang Ren , Hua Xu , Vipina K. Keloth

Early detection of Alzheimer's Dementia (AD) and Mild Cognitive Impairment (MCI) is critical for timely intervention, yet current diagnostic approaches remain resource-intensive and invasive. Speech, encompassing both acoustic and…

Independent component analysis (ICA) of multi-subject functional magnetic resonance imaging (fMRI) data has proven useful in providing a fully multivariate summary that can be used for multiple purposes. ICA can identify patterns that can…

Neurons and Cognition · Quantitative Biology 2022-11-15 Fateme Ghayem , Hanlu Yang , Furkan Kantar , Seung-Jun Kim , Vince D. Calhoun , Tulay Adali

Deep learning systems have been reported to acheive state-of-the-art performances in many applications, and one of the keys for achieving this is the existence of well trained classifiers on benchmark datasets which can be used as backbone…

Machine Learning · Computer Science 2022-10-04 Jirong Yi , Qiaosheng Zhang , Zhen Chen , Qiao Liu , Wei Shao

Early prediction of Mild Cognitive Impairment (MCI) conversion is hampered by a trade-off between immediacy--making fast predictions from a single baseline sMRI--and accuracy--leveraging longitudinal scans to capture disease progression. We…

Machine Learning · Computer Science 2025-06-09 Zhihao Tang , Chaozhuo Li , Litian Zhang , Xi Zhang