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Phylogenetic placement refers to a family of tools and methods to analyze, visualize, and interpret the tsunami of metagenomic sequencing data generated by high-throughput sequencing. Compared to alternative (e. g., similarity-based)…

Populations and Evolution · Quantitative Biology 2025-01-09 Lucas Czech , Alexandros Stamatakis , Micah Dunthorn , Pierre Barbera

The number of studies that combine Evolutionary Machine Learning and self-supervised learning has been growing steadily in recent years. Evolutionary Machine Learning has been shown to help automate the design of machine learning algorithms…

Neural and Evolutionary Computing · Computer Science 2025-11-05 Adriano Vinhas , João Correia , Penousal Machado

Genetic algorithms are a well-known example of bio-inspired heuristic methods. They mimic natural selection by modeling several operators such as mutation, crossover, and selection. Recent discoveries about Epigenetics regulation processes…

Neural and Evolutionary Computing · Computer Science 2023-03-20 Mohamed Djallel Dilmi , Hanene Azzag , Mustapha Lebbah

Feature selection is an intractable problem, therefore practical algorithms often trade off the solution accuracy against the computation time. In this paper, we propose a novel multi-stage feature selection framework utilizing multiple…

Machine Learning · Computer Science 2021-11-18 Mohammed Ghaith Altarabichi , Sławomir Nowaczyk , Sepideh Pashami , Peyman Sheikholharam Mashhad

Reconciling a gene tree with a species tree is an important task that reveals much about the evolution of genes, genomes, and species, as well as about the molecular function of genes. A wide array of computational tools have been devised…

Populations and Evolution · Quantitative Biology 2012-12-11 Yun Yu , Luay Nakhleh

In evolutionary biology, the speciation history of living organisms is represented graphically by a phylogeny, that is, a rooted tree whose leaves correspond to current species and branchings indicate past speciation events. Phylogenies are…

Populations and Evolution · Quantitative Biology 2019-08-02 Wai-Tong Louis Fan , Sebastien Roch

Phylogenetic trees (i.e. evolutionary trees, additive trees or X-trees) play a key role in the processes of modeling and representing species evolution. Genome evolution of a given group of species is usually modeled by a species…

Populations and Evolution · Quantitative Biology 2023-01-03 Vladimir Makarenkov , Gayane S. Barseghyan , Nadia Tahiri

Clusters of genes that have evolved by repeated segmental duplication present difficult challenges throughout genomic analysis, from sequence assembly to functional analysis. Improved understanding of these clusters is of utmost importance,…

Machine Learning · Computer Science 2010-01-25 Tomáš Vinař , Broňa Brejová , Giltae Song , Adam Siepel

Following genetic ancestry in eukaryote populations poses several open problems due to sexual reproduction and recombination. The history of extant genetic material is usually modeled backwards in time, but tracking chromosomes at a large…

Populations and Evolution · Quantitative Biology 2025-06-23 Juliette Luiselli , Manuel Lafond

Evolution, the engine behind the survival and growth of life on Earth, operates through the population-based process of reproduction. Inspired by this principle, this paper formally defines a newly emerging problem -- the population-based…

Computation and Language · Computer Science 2025-03-10 Yiqun Zhang , Peng Ye , Xiaocui Yang , Shi Feng , Shufei Zhang , Lei Bai , Wanli Ouyang , Shuyue Hu

Phylogenetic comparative methods may fail to produce meaningful results when either the underlying model is inappropriate or the data contain insufficient information to inform the inference. The ability to measure the statistical power of…

Quantitative Methods · Quantitative Biology 2012-07-26 Carl Boettiger , Graham Coop , Peter Ralph

The effectiveness of machine learning models, particularly in unbalanced classification tasks, is often hindered by the failure to differentiate between critical instances near the decision boundary and redundant samples concentrated in the…

Machine Learning · Computer Science 2025-09-25 Samir Brahim Belhaouari , Yunis Carreon Kahalan , Humaira Shaffique , Ismael Belhaouari , Ashhadul Islam

Bayesian inference is now a leading technique for reconstructing phylogenetic trees from aligned sequence data. In this short note, we formally show that the maximum posterior tree topology provides a statistically consistent estimate of a…

Populations and Evolution · Quantitative Biology 2013-07-12 Mike Steel

Ancestral sequence reconstruction is a key task in computational biology. It consists in inferring a molecular sequence at an ancestral species of a known phylogeny, given descendant sequences at the tip of the tree. In addition to its many…

Populations and Evolution · Quantitative Biology 2022-07-27 Brandon Legried , Sebastien Roch

Evolutionary Algorithms are naturally inspired approximation optimisation algorithms that usually interfere with science problems when common mathematical methods are unable to provide a good solution or finding the exact solution requires…

Artificial Intelligence · Computer Science 2021-02-03 Mohammed ElKomy

Computational phylogenetics has become an established tool in historical linguistics, with many language families now analyzed using likelihood-based inference. However, standard approaches rely on expert-annotated cognate sets, which are…

Computation and Language · Computer Science 2026-03-30 Gerhard Jäger

Finding the best configuration of algorithms' hyperparameters for a given optimization problem is an important task in evolutionary computation. We compare in this work the results of four different hyperparameter tuning approaches for a…

Neural and Evolutionary Computing · Computer Science 2022-03-18 Furong Ye , Carola Doerr , Hao Wang , Thomas Bäck

Phylogenetics is now fundamental in life sciences, providing insights into the earliest branches of life and the origins and spread of epidemics. However, finding suitable phylogenies from the vast space of possible trees remains…

Populations and Evolution · Quantitative Biology 2024-01-24 Matthew J Penn , Neil Scheidwasser , Joseph Penn , Christl A Donnelly , David A Duchêne , Samir Bhatt

In computational phylogenetics, the problem of constructing a supertree of a given set of rooted input trees can be formalized in different ways, to cope with contradictory information in the input. We consider the Minimum Flip Supertree…

Data Structures and Algorithms · Computer Science 2011-04-25 Sebastian Böcker

There is now significant historical data available on decision making in organizations, consisting of the decision problem, what decisions were made, and how desirable the outcomes were. Using this data, it is possible to learn a surrogate…

Neural and Evolutionary Computing · Computer Science 2020-04-23 Olivier Francon , Santiago Gonzalez , Babak Hodjat , Elliot Meyerson , Risto Miikkulainen , Xin Qiu , Hormoz Shahrzad