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When testing for the association of a single SNP with a phenotypic response, one usually considers an additive genetic model, assuming that the mean of of the response for the heterozygous state is the average of the means for the two…

Methodology · Statistics 2025-01-07 Dominic Edelmann , Fernando Castro-Prado , Jelle J. Goeman

We investigate two closely related nonparametric hypothesis testing problems. In the first problem (i.e., the existence problem), we test whether a testing data stream is generated by one of a set of composite distributions. In the second…

Signal Processing · Electrical Eng. & Systems 2018-12-05 Yixian Liu , Yingbin Liang , Shuguang Cui

High dimensional hypothesis test deals with models in which the number of parameters is significantly larger than the sample size. Existing literature develops a variety of individual tests. Some of them are sensitive to the dense and small…

Statistics Theory · Mathematics 2018-08-09 Cheng Zhou , Xinsheng Zhang , Wenxin Zhou , Han Liu

We study the coboundary expansion property of product codes called product expansion, which played a key role in all recent constructions of good qLDPC codes. It was shown before that this property is equivalent to robust testability and…

Information Theory · Computer Science 2023-08-08 Gleb Kalachev

In the problem of classical group testing one aims to identify a small subset (of size $d$) diseased individuals/defective items in a large population (of size $n$). This process is based on a minimal number of suitably-designed group tests…

Information Theory · Computer Science 2022-09-26 Xiwei Cheng , Sidharth Jaggi , Qiaoqiao Zhou

The large bulk of work in multiple testing has focused on specifying procedures that control the false discovery rate (FDR), with relatively less attention being paid to the corresponding Type II error known as the false non-discovery rate…

Statistics Theory · Mathematics 2020-05-11 Max Rabinovich , Michael I. Jordan , Martin J. Wainwright

We consider linear regression in the high-dimensional regime where the number of observations $n$ is smaller than the number of parameters $p$. A very successful approach in this setting uses $\ell_1$-penalized least squares (a.k.a. the…

Methodology · Statistics 2014-02-05 Adel Javanmard , Andrea Montanari

Small set expansion in high dimensional expanders is of great importance, e.g., towards proving cosystolic expansion, local testability of codes and constructions of good quantum codes. In this work we improve upon the state of the art…

Computational Complexity · Computer Science 2025-12-12 Tali Kaufman , David Mass

Motivated by differential co-expression analysis in genomics, we consider in this paper estimation and testing of high-dimensional differential correlation matrices. An adaptive thresholding procedure is introduced and theoretical…

Methodology · Statistics 2015-10-22 T. Tony Cai , Anru Zhang

In this paper, we introduce a variation of the group testing problem capturing the idea that a positive test requires a combination of multiple ``types'' of item. Specifically, we assume that there are multiple disjoint \emph{semi-defective…

Information Theory · Computer Science 2024-05-10 Thach V. Bui , Jonathan Scarlett

Model-X knockoffs is a general procedure that can leverage any feature importance measure to produce a variable selection algorithm, which discovers true effects while rigorously controlling the number or fraction of false positives.…

Methodology · Statistics 2020-12-07 Zhimei Ren , Yuting Wei , Emmanuel Candès

Generalized linear mixed models (GLMMs) are used to model responses from exponential families with a combination of fixed and random effects. For variance components in GLMMs, we propose an approximate restricted likelihood ratio test that…

Methodology · Statistics 2019-06-11 Stephanie T. Chen , Luo Xiao , Ana-Maria Staicu

A large class of spatial models contains intractable normalizing functions, such as spatial lattice models, interaction spatial point processes, and social network models. Bayesian inference for such models is challenging since the…

Methodology · Statistics 2026-01-05 Jong Hyeon Lee , Jongmin Kim , Heesang Lee , Jaewoo Park

We propose a new algorithmic framework, called "partial rejection sampling", to draw samples exactly from a product distribution, conditioned on none of a number of bad events occurring. Our framework builds (perhaps surprising) new…

Data Structures and Algorithms · Computer Science 2019-01-16 Heng Guo , Mark Jerrum , Jingcheng Liu

In this paper, we investigate the adequacy testing problem of high-dimensional factor-augmented regression model. Existing test procedures perform not well under dense alternatives. To address this critical issue, we introduce a novel…

Methodology · Statistics 2025-04-04 Yanmei Shi , Leheng Cai , Xu Guo , Shurong Zheng

In this paper we consider an acceptance-rejection (AR) sampler based on deterministic driver sequences. We prove that the discrepancy of an $N$ element sample set generated in this way is bounded by $\mathcal{O} (N^{-2/3}\log N)$, provided…

Numerical Analysis · Mathematics 2016-04-18 Houying Zhu , Josef Dick

The dynamic behavior of jointed assemblies exhibiting friction nonlinearities features amplitude-dependent dissipation and stiffness. To develop numerical simulations for predictive and design purposes, macro-scale High Fidelity Models…

Computational Engineering, Finance, and Science · Computer Science 2022-04-27 Ahmed Amr Morsy , Mariella Kast , Paolo Tiso

We present a method for approximating solutions of Stochastic Differential Equations (SDEs) with arbitrary rates. This approximation is derived for bounded and measurable test functions. Specifically, we demonstrate that, leveraging the…

Probability · Mathematics 2024-03-27 Clément Rey

This paper proposes and analyzes a dampened proximal alternating direction method of multipliers (DP.ADMM) for solving linearly-constrained nonconvex optimization problems where the smooth part of the objective function is nonseparable.…

Optimization and Control · Mathematics 2023-01-05 Weiwei Kong , Renato D. C. Monteiro

The standard paired-sample testing approach in the multidimensional setting applies multiple univariate tests on the individual features, followed by p-value adjustments. Such an approach suffers when the data carry numerous features. A…

Machine Learning · Statistics 2023-09-29 Ioannis Bargiotas , Argyris Kalogeratos , Nicolas Vayatis