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Mediation analysis in causal inference typically concentrates on one binary exposure, using deterministic interventions to split the average treatment effect into direct and indirect effects through a single mediator. Yet, real-world…

Methodology · Statistics 2023-07-07 David B. McCoy , Alan E. Hubbard , Mark van der Laan , Alejandro Schuler

How do we know if communication is emerging in a multi-agent system? The vast majority of recent papers on emergent communication show that adding a communication channel leads to an increase in reward or task success. This is a useful…

Machine Learning · Computer Science 2019-03-14 Ryan Lowe , Jakob Foerster , Y-Lan Boureau , Joelle Pineau , Yann Dauphin

As the most important tool to provide high-level evidence-based medicine, researchers can statistically summarize and combine data from multiple studies by conducting meta-analysis. In meta-analysis, mean differences are frequently used…

Methodology · Statistics 2018-01-30 Dehui Luo , Xiang Wan , Jiming Liu , Tiejun Tong

Interim analyses for group-sequential decision making are prevalent in clinical trials. Methodology is well established and has been routinely implemented over the last decades. Still, confusions and uncertainties on aspects of how to…

Accurate estimation of treatment effects is essential for decision-making across various scientific fields. This task, however, becomes challenging in areas like social sciences and online marketplaces, where treating one experimental unit…

Machine Learning · Computer Science 2025-02-04 Mohsen Bayati , Yuwei Luo , William Overman , Sadegh Shirani , Ruoxuan Xiong

Meta-analysis can be a critical part of the research process, often serving as the primary analysis on which the practitioners, policymakers, and individuals base their decisions. However, current literature synthesis approaches to…

Methodology · Statistics 2023-08-28 Lily H. Zhang , Menelaos Konstantinidis , Marie-Abèle Bind , Donald B. Rubin

Biological and artificial information processing systems form representations of the world that they can use to categorize, reason, plan, navigate, and make decisions. How can we measure the similarity between the representations formed by…

Causal mediation analysis is a useful tool for epidemiological research, but it has been criticized for relying on a "cross-world" independence assumption that is empirically difficult to verify and problematic to justify based on…

Methodology · Statistics 2021-09-02 Ryan M. Andrews , Vanessa Didelez

Mediation analysis is a useful tool to evaluate surrogate endpoints in clinical trials. We propose a novel method, the M-survival learner, for estimating heterogeneous indirect treatment effects in the presence of censored outcomes. The…

Methodology · Statistics 2026-04-16 Xingyu Li , Qing Liu , Xun Jiang , Hong Amy Xia , Brian P. Hobbs , Peng Wei

Causal mediation analysis aims at disentangling a treatment effect into an indirect mechanism operating through an intermediate outcome or mediator, as well as the direct effect of the treatment on the outcome of interest. However, the…

Econometrics · Economics 2020-05-05 Martin Huber , Lukáš Lafférs

Mediation analytics help examine if and how an intermediate variable mediates the influence of an exposure variable on an outcome of interest. Quantiles, rather than the mean, of an outcome are scientifically relevant to the comparison…

Methodology · Statistics 2024-12-23 Canyi Chen , Yinqiu He , Huixia J. Wang , Gongjun Xu , Peter X. -K. Song

A new method is proposed to explore sources of cross-site impact variance in multi-site trials of social interventions. With this approach, aggregate reports from participants in the treatment arm about the treatment experience are used to…

Applications · Statistics 2021-12-03 David R. Judkins , Gabriel Durham

The use of social robots as instruments for social mediation has been gaining traction in the field of Human-Robot Interaction (HRI). So far, the design of such robots and their behaviors is often driven by technological platforms and…

Causal mediation analysis provides techniques for defining and estimating effects that may be endowed with mechanistic interpretations. With many scientific investigations seeking to address mechanistic questions, causal direct and indirect…

The ability to recognize weakness of students and solving any problem may confront them in timely fashion is always a target of all educational institutions. This study was designed to explore how can predictive and statistical analysis…

Other Computer Science · Computer Science 2016-01-19 Mohammed Al-Sarem

Context: Safety analysis is a predominant activity in developing safety-critical systems. It is a highly cooperative task among multiple functional departments due to increasingly sophisticated safety-critical systems and close-knit…

Software Engineering · Computer Science 2019-04-12 Yang Wang , Daniel Graziotin , Stefan Kriso , Stefan Wagner

How should researchers conduct causal inference when the outcome of interest is latent and measured imperfectly by multiple indicators? We develop a general nonparametric framework for identifying and estimating average treatment effects on…

Methodology · Statistics 2026-04-22 Jiawei Fu , Donald P. Green

Mediation analysis is widely used in health science research to evaluate the extent to which an intermediate variable explains an observed exposure-outcome relationship. However, the validity of analysis can be compromised when the exposure…

Methodology · Statistics 2025-03-06 Chao Cheng , Donna Spiegelman , Fan Li

Random-effects meta-analyses of observational studies can produce biased estimates if the synthesized studies are subject to unmeasured confounding. We propose sensitivity analyses quantifying the extent to which unmeasured confounding of…

Methodology · Statistics 2017-10-10 Maya B. Mathur , Tyler J. VanderWeele

Text data are being used as a lens through which human cognition can be studied at a large scale. Methods like emotion analysis are now in the standard toolkit of computational social scientists but typically rely on third-person annotation…

Computation and Language · Computer Science 2020-06-17 Bennett Kleinberg