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Image domain prior models have been shown to improve the quality of reconstructed images, especially when data are limited. Pre-processing of raw data, through the implicit or explicit inclusion of data domain priors have separately also…
Positron emission tomography (PET) is a critical tool for diagnosing tumors and neurological disorders but poses radiation risks to patients, particularly to sensitive populations. While reducing injected radiation dose mitigates this risk,…
With the development of computed tomography (CT) imaging technology, it is possible to acquire multi-energy data by spectral CT. Being different from conventional CT, the X-ray energy spectrum of spectral CT is cutting into several narrow…
Computed Tomography (CT) is widely used in healthcare for detailed imaging. However, Low-dose CT, despite reducing radiation exposure, often results in images with compromised quality due to increased noise. Traditional methods, including…
Quantitative imaging is an important feature of spectral X-ray and CT systems, especially photon-counting CT (PCCT) imaging systems, which is achieved through material decomposition (MD) using spectral measurements. In this work, we present…
Computational tomography (CT) provides high-resolution medical imaging, but it can expose patients to high radiation. X-ray scanners have low radiation exposure, but their resolutions are low. This paper proposes a new conditional diffusion…
Computed tomography (CT) can provide a 3D view of the patient's internal organs, facilitating disease diagnosis, but it incurs more radiation dose to a patient and a CT scanner is much more cost prohibitive than an X-ray machine too.…
The potential huge advantage of spectral computed tomography (CT) is its capability to provide accuracy material identification and quantitative tissue information. This can benefit clinical applications, such as brain angiography, early…
Many spectral CT applications require accurate material decomposition. Existing material decomposition algorithms are often susceptible to significant noise magnification or, in the case of one-step model-based approaches, hampered by slow…
Computed Tomography (CT) technology reduces radiation haz-ards to the human body through sparse sampling, but fewer sampling angles pose challenges for image reconstruction. Score-based generative models are widely used in sparse-view CT…
Breast cancer is the most frequently diagnosed human cancer in the United States at present. Early detection is crucial for its successful treatment. X-ray mammography and digital breast tomosynthesis are currently the main methods for…
Like in many other research fields, recent developments in computational imaging have focused on developing machine learning (ML) approaches to tackle its main challenges. To improve the performance of computational imaging algorithms,…
Computed Tomography (CT) is a medical imaging modality that can generate more informative 3D images than 2D X-rays. However, this advantage comes at the expense of more radiation exposure, higher costs, and longer acquisition time. Hence,…
Kidney DCE-MRI aims at both qualitative assessment of kidney anatomy and quantitative assessment of kidney function by estimating the tracer kinetic (TK) model parameters. Accurate estimation of TK model parameters requires an accurate…
Cone-beam computed tomography (CBCT) offers advantages over conventional fan-beam CT in that it requires a shorter time and less exposure to obtain images. CBCT has found a wide variety of applications in patient positioning for…
Inspired by the success of deep learning applications on restoration of low-dose and sparse CT images, we propose a novel method to reconstruct high-quality 4D cone-beam CT (4DCBCT) images from sparse datasets. Our approach combines the…
Multi-contrast (MC) Magnetic Resonance Imaging (MRI) reconstruction aims to incorporate a reference image of auxiliary modality to guide the reconstruction process of the target modality. Known MC reconstruction methods perform well with a…
Inverse problems spanning four or more dimensions such as space, time and other independent parameters have become increasingly important. State-of-the-art 4D reconstruction methods use model based iterative reconstruction (MBIR), but…
Computed Tomography (CT) is an essential non-destructive three dimensional imaging modality used in medicine, security screening, and inspection of manufactured components. Typical CT data acquisition entails the collection of a thousand or…
A major challenge for medical X-ray CT imaging is reducing the number of X-ray projections to lower radiation dosage and reduce scan times without compromising image quality. However these under-determined inverse imaging problems rely on…