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Dementia is a syndrome characterised by the decline of different cognitive abilities. Alzheimer's Disease (AD) is the most common dementia affecting cognitive domains such as memory and learning, perceptual-motion or executive function.…

Computer Vision and Pattern Recognition · Computer Science 2018-10-26 Juan Manuel Fernández Montenegro

Machine learning methods exploiting multi-parametric biomarkers, especially based on neuroimaging, have huge potential to improve early diagnosis of dementia and to predict which individuals are at-risk of developing dementia. To benchmark…

Machine Learning · Computer Science 2022-02-21 Esther E. Bron , Stefan Klein , Annika Reinke , Janne M. Papma , Lena Maier-Hein , Daniel C. Alexander , Neil P. Oxtoby

Alzheimer's disease (AD) and its prodromal stage, Mild Cognitive Impairment (MCI), are associated with subtle declines in memory, attention, and language that often go undetected until late in progression. Traditional diagnostic tools such…

Human-Computer Interaction · Computer Science 2025-12-30 Ananya Drishti , Mahfuza Farooque

Cognitive impairment (CI) is of growing public health concern, and early detection is vital for effective intervention. Speech has gained attention as a non-invasive and easily collectible biomarker for assessing cognitive decline.…

Sound · Computer Science 2025-06-24 Mostafa Shahin , Beena Ahmed , Julien Epps

Speech is usually used for constructing an automatic Alzheimer's dementia (AD) detection system, as the acoustic and linguistic abilities show a decline in people living with AD at the early stages. However, speech includes not only…

Audio and Speech Processing · Electrical Eng. & Systems 2024-10-11 Yilin Pan , Yanpei Shi , Yijia Zhang , Mingyu Lu

Predicting Mild Cognitive Impairment (MCI) is currently a challenge as existing diagnostic criteria rely on neuropsychological examinations. Automated Machine Learning (ML) models that are trained on verbal utterances of MCI patients can…

Computation and Language · Computer Science 2015-12-11 Sylvester Olubolu Orimaye , Kah Yee Tai , Jojo Sze-Meng Wong , Chee Piau Wong

This paper presents the EACare project, an ambitious multi-disciplinary collaboration with the aim to develop an embodied system, capable of carrying out neuropsychological tests to detect early signs of dementia, e.g., due to Alzheimer's…

Objective: This study aimed to evaluate which voice features can predict health deterioration in patients with chronic HF. Background: Heart failure (HF) is a chronic condition with progressive deterioration and acute decompensations, often…

In this paper, we exploit a Fully Convolutional Network (FCN) to analyze the audio data of spontaneous speech for dementia detection. A fully convolutional network accommodates speech samples with varying lengths, thus enabling us to…

Audio and Speech Processing · Electrical Eng. & Systems 2020-08-18 Youxiang Zhu , Xiaohui Liang

Alzheimers disease is a deadly neurological condition, impairing important memory and brain functions. Alzheimers disease promotes brain shrinkage, ultimately leading to dementia. Dementia diagnosis typically takes 2.8 to 4.4 years after…

In light of the growing proportion of older individuals in our society, the timely diagnosis of Alzheimer's disease has become a crucial aspect of healthcare. In this paper, we propose a non-invasive and cost-effective detection method…

Human-Computer Interaction · Computer Science 2025-01-03 Tian Zheng , Xurong Xie , Xiaolan Peng , Hui Chen , Feng Tian

Neurodegenerative diseases are frequently associated with structural changes in the brain. Magnetic Resonance Imaging (MRI) scans can show these variations and therefore be used as a supportive feature for a number of neurodegenerative…

Dementia is associated with various cognitive impairments and typically manifests only after significant progression, making intervention at this stage often ineffective. To address this issue, the Prediction and Recognition of Cognitive…

Automated detection of voice disorders with computational methods is a recent research area in the medical domain since it requires a rigorous endoscopy for the accurate diagnosis. Efficient screening methods are required for the diagnosis…

Quantitative Methods · Quantitative Biology 2018-12-06 Vibhuti Gupta

With populations ageing, the number of people with dementia worldwide is expected to triple to 152 million by 2050. Seventy percent of cases are due to Alzheimer's disease (AD) pathology and there is a 10-20 year 'pre-clinical' period…

Artificial Intelligence · Computer Science 2021-04-30 Renjie Li , Xinyi Wang , Katherine Lawler , Saurabh Garg , Quan Bai , Jane Alty

Alzheimer's disease (AD) constitutes a neurodegenerative disease with serious consequences to peoples' everyday lives, if it is not diagnosed early since there is no available cure. Alzheimer's is the most common cause of dementia, which…

Computation and Language · Computer Science 2023-01-18 Loukas Ilias , Dimitris Askounis , John Psarras

Current approaches to detecting depression and anxiety from speech primarily rely on machine learning techniques that utilize hand-engineered paralinguistic features and related acoustic descriptors derived from time- and frequency-domain…

Machine Learning · Computer Science 2026-05-12 Oleksii Abramenko , Noah D. Stein , Colin Vaz

Early dementia diagnosis requires biomarkers sensitive to both structural and functional brain changes. While structural neuroimaging biomarkers have progressed significantly, objective functional biomarkers of early cognitive decline…

Neurons and Cognition · Quantitative Biology 2025-04-16 Tomasz M. Rutkowski , Stanisław Narębski , Mihoko Otake-Matsuura , Tomasz Komendziński

Alzheimer's disease (AD) is a neurodegenerative disease that affects nearly 50 million individuals across the globe and is one of the leading causes of deaths globally. It is projected that by 2050, the number of people affected by the…

Machine Learning · Computer Science 2021-10-26 Yash Kumar , Piyush Maheshwari , Shreyansh Joshi , Veeky Baths

The global prevalence of dementia is projected to double by 2050, highlighting the urgent need for scalable diagnostic tools. This study utilizes digital cognitive tasks with eye-tracking data correlated with memory processes to distinguish…

Human-Computer Interaction · Computer Science 2025-08-28 Tomás Silva Santos Rocha , Anastasiia Mikhailova , Moreno I. Coco , José Santos-Victor