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Related papers: Health-LLM: Personalized Retrieval-Augmented Disea…

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Background: Large language models (LLMs) such as OpenAI's GPT-4 or Google's PaLM 2 are proposed as viable diagnostic support tools or even spoken of as replacements for "curbside consults". However, even LLMs specifically trained on medical…

Artificial Intelligence · Computer Science 2024-10-21 Gioele Barabucci , Victor Shia , Eugene Chu , Benjamin Harack , Nathan Fu

Emerging topics in biomedical research are continuously expanding, providing a wealth of information about genes and their function. This rapid proliferation of knowledge presents unprecedented opportunities for scientific discovery and…

Genomics · Quantitative Biology 2024-12-25 Zhijian Chen , Chuan Hu , Min Wu , Qingqing Long , Xuezhi Wang , Yuanchun Zhou , Meng Xiao

The proliferation of Large Language Models (LLMs) in high-stakes applications such as medical (self-)diagnosis and preliminary triage raises significant ethical and practical concerns about the effectiveness, appropriateness, and possible…

Computers and Society · Computer Science 2025-06-18 Bonam Mingole , Aditya Majumdar , Firdaus Ahmed Choudhury , Jennifer L. Kraschnewski , Shyam S. Sundar , Amulya Yadav

This paper explores the development of the Six Stages of Information Search Model and its enhancement through the application of the Large Language Model (LLM) powered Information Search Processes (ISP) in healthcare. The Six Stages Model,…

Information Retrieval · Computer Science 2024-07-03 Forhan Bin Emdad , Mohammad Ishtiaque Rahman

Large language models (LLMs) are increasingly deployed across healthcare applications, including clinical documentation, diagnostic reasoning, medicine recommendation, and medical education. Their outputs are largely unstructured clinical…

Computers and Society · Computer Science 2026-05-26 Lingyao Li , Deyi Li , Chen Chen , Renkai Ma , Runlong Yu , Mingquan Lin , Rui Yin , Lizhou Fan , Cathy Shyr , Siyuan Ma , Mei Liu , Steven Bethard

In response to the success of proprietary Large Language Models (LLMs) such as OpenAI's GPT-4, there is a growing interest in developing open, non-proprietary LLMs and AI foundation models (AIFMs) for transparent use in academic,…

Computation and Language · Computer Science 2025-02-10 Mahdi Alkaeed , Sofiat Abioye , Adnan Qayyum , Yosra Magdi Mekki , Ilhem Berrou , Mohamad Abdallah , Ala Al-Fuqaha , Muhammad Bilal , Junaid Qadir

Effective patient care in digital healthcare requires large language models (LLMs) that not only answer questions but also actively gather critical information through well-crafted inquiries. This paper introduces HealthQ, a novel framework…

Computation and Language · Computer Science 2025-02-26 Ziyu Wang , Hao Li , Di Huang , Hye-Sung Kim , Chae-Won Shin , Amir M. Rahmani

The extraction of lung lesion information from clinical and medical imaging reports is crucial for research on and clinical care of lung-related diseases. Large language models (LLMs) can be effective at interpreting unstructured text in…

Computation and Language · Computer Science 2024-11-18 Diya Li , Asim Kadav , Aijing Gao , Rui Li , Richard Bourgon

Large language models (LLMs) have emerged as powerful tools for medical information retrieval, yet their accuracy and depth remain limited in specialized domains such as Alzheimer's disease (AD), a growing global health challenge. To…

Radiology report generation (RRG) models typically focus on individual exams, often overlooking the integration of historical visual or textual data, which is crucial for patient follow-ups. Traditional methods usually struggle with long…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Tengfei Liu , Jiapu Wang , Yongli Hu , Mingjie Li , Junfei Yi , Xiaojun Chang , Junbin Gao , Baocai Yin

Clinical decision-making is inherently complex, often influenced by cognitive biases, incomplete information, and case ambiguity. Large Language Models (LLMs) have shown promise as tools for supporting clinical decision-making, yet their…

Machine Learning · Computer Science 2025-07-10 Burcu Sayin , Ipek Baris Schlicht , Ngoc Vo Hong , Sara Allievi , Jacopo Staiano , Pasquale Minervini , Andrea Passerini

Recent advances in Retrieval-Augmented Generation (RAG) have enabled large language models (LLMs) to ground outputs in clinical evidence. However, connecting LLMs with external databases introduces the risk of contextual leakage: a subtle…

Computation and Language · Computer Science 2026-03-17 Shaowei Guan , Yu Zhai , Hin Chi Kwok , Jiawei Du , Xinyu Feng , Jing Li , Harry Qin , Vivian Hui

Large language models (LLMs) holds significant promise in achieving general medication recommendation systems owing to their comprehensive interpretation of clinical notes and flexibility to medication encoding. We evaluated both…

Information Retrieval · Computer Science 2025-08-05 Zihao Zhao , Chenxiao Fan , Junlong Liu , Zheng Wang , Xiangnan He , Chongming Gao , Juan Li , Fuli Feng

The transcription of medical monologues, especially those containing a high density of specialized terminology and delivered with a distinct accent, presents a significant challenge for existing automated systems. This paper introduces a…

Computation and Language · Computer Science 2024-10-08 Jiafeng Li , Yanda Mu

We present PhysioLLM, an interactive system that leverages large language models (LLMs) to provide personalized health understanding and exploration by integrating physiological data from wearables with contextual information. Unlike…

Human-Computer Interaction · Computer Science 2024-06-28 Cathy Mengying Fang , Valdemar Danry , Nathan Whitmore , Andria Bao , Andrew Hutchison , Cayden Pierce , Pattie Maes

Large language models (LLMs) show promise for supporting clinical decision-making in complex fields such as rheumatology. Our evaluation shows that smaller language models (SLMs), combined with retrieval-augmented generation (RAG), achieve…

Computation and Language · Computer Science 2025-07-11 Sabine Felde , Rüdiger Buchkremer , Gamal Chehab , Christian Thielscher , Jörg HW Distler , Matthias Schneider , Jutta G. Richter

Large Language Models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence (AI) technology which is rapidly evolving and promises to aid in medical diagnosis either by assisting doctors or by simulating a doctor's…

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

With the rapid advancement of generative artificial intelligence, large language models (LLMs) are increasingly adopted in industrial domains, offering new opportunities for Prognostics and Health Management (PHM). These models help address…

Artificial Intelligence · Computer Science 2025-08-05 Puyu Yang , Laifa Tao , Zijian Huang , Haifei Liu , Wenyan Cao , Hao Ji , Jianan Qiu , Qixuan Huang , Xuanyuan Su , Yuhang Xie , Jun Zhang , Shangyu Li , Chen Lu , Zhixuan Lian

Mobile and wearable healthcare monitoring play a vital role in facilitating timely interventions, managing chronic health conditions, and ultimately improving individuals' quality of life. Previous studies on large language models (LLMs)…

Artificial Intelligence · Computer Science 2025-10-01 Xin Wang , Ting Dang , Xinyu Zhang , Vassilis Kostakos , Michael J. Witbrock , Hong Jia