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Latent space models are widely used for analyzing high-dimensional discrete data matrices, such as patient-feature matrices in electronic health records (EHRs), by capturing complex dependence structures through low-dimensional embeddings.…

Machine Learning · Computer Science 2026-02-19 Weijing Tang , Ming Yuan , Zongqi Xia , Tianxi Cai

As two important textual modalities in electronic health records (EHR), both structured data (clinical codes) and unstructured data (clinical narratives) have recently been increasingly applied to the healthcare domain. Most existing…

Computation and Language · Computer Science 2022-11-01 Sicen Liu , Xiaolong Wang , Yongshuai Hou , Ge Li , Hui Wang , Hui Xu , Yang Xiang , Buzhou Tang

Recurrent Neural Networks (RNNs) have achieved remarkable performance on a range of tasks. A key step to further empowering RNN-based approaches is improving their explainability and interpretability. In this work we present MEME: a model…

Machine Learning · Computer Science 2021-04-15 Dmitry Kazhdan , Botty Dimanov , Mateja Jamnik , Pietro Liò

Early detection of preventable diseases is important for better disease management, improved inter-ventions, and more efficient health-care resource allocation. Various machine learning approacheshave been developed to utilize information…

Machine Learning · Computer Science 2018-08-16 Jingshu Liu , Zachariah Zhang , Narges Razavian

In this paper, we investigate a new approach to Population, Intervention and Outcome (PIO) element detection, a common task in Evidence Based Medicine (EBM). The purpose of this study is two-fold: to build a training dataset for PIO element…

Computation and Language · Computer Science 2019-06-27 Hichem Mezaoui , Aleksandr Gontcharov , Isuru Gunasekara

Electronic Health Records (EHRs) offer considerable potential for clinical prediction, but their complexity and heterogeneity challenge traditional machine learning. Domain-specific EHR foundation models trained on unlabeled EHR data have…

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

Machine Learning · Computer Science 2025-08-29 Rituparna Datta , Jiaming Cui , Zihan Guan , Vishal G. Reddy , Joshua C. Eby , Gregory Madden , Rupesh Silwal , Anil Vullikanti

In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

Quantitative Methods · Quantitative Biology 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu

Electronic Health Records (EHRs) enable deep learning for clinical predictions, but the optimal method for representing patient data remains unclear due to inconsistent evaluation practices. We present the first systematic benchmark to…

Machine Learning · Computer Science 2025-10-13 Tianyi Chen , Mingcheng Zhu , Zhiyao Luo , Tingting Zhu

Early diagnosis of disease can lead to improved health outcomes, including higher survival rates and lower treatment costs. With the massive amount of information available in electronic health records (EHRs), there is great potential to…

Machine Learning · Computer Science 2022-08-02 Asem Alaa , Erik Mayer , Mauricio Barahona

Electronic health records (EHRs) form an invaluable resource for training clinical decision support systems. To leverage the potential of such systems in high-risk applications, we need large, structured tabular datasets on which we can…

Artificial Intelligence · Computer Science 2025-11-24 Paloma Rabaey , Adrick Tench , Stefan Heytens , Thomas Demeester

Multimodal Large Language Models (MLLMs) have shown transformative potential in medical applications, yet their performance is hindered by conventional data curation strategies that rely on coarse-grained partitioning by modality or…

Computation and Language · Computer Science 2026-04-29 Jianghang Lin , Haihua Yang , Deli Yu , Kai Wu , Kai Ye , Jinghao Lin , Zihan Wang , Yuhang Wu , Liujuan Cao

Sentence embedding tasks are important in natural language processing (NLP), but improving their performance while keeping them reliable is still hard. This paper presents a framework that combines pseudo-label generation and model ensemble…

Computation and Language · Computer Science 2025-01-28 Ziwei Liu , Qi Zhang , Lifu Gao

The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

Computation and Language · Computer Science 2023-12-08 Angeela Acharya , Sulabh Shrestha , Anyi Chen , Joseph Conte , Sanja Avramovic , Siddhartha Sikdar , Antonios Anastasopoulos , Sanmay Das

Healthcare data now span EHRs, medical imaging, genomics, and wearable sensors, but most diagnostic models still process these modalities in isolation. This limits their ability to capture early, cross-modal disease signatures. This paper…

Machine Learning · Computer Science 2025-12-18 Md Talha Mohsin , Ismail Abdulrashid

The wide adoption of Electronic Health Records (EHR) has resulted in large amounts of clinical data becoming available, which promises to support service delivery and advance clinical and informatics research. Deep learning techniques have…

Machine Learning · Computer Science 2022-02-14 Thanh Nguyen-Duc , Natasha Mulligan , Gurdeep S. Mannu , Joao H. Bettencourt-Silva

Artificial intelligence (AI) tools for radiology are commonly unmonitored once deployed. The lack of real-time case-by-case assessments of AI prediction confidence requires users to independently distinguish between trustworthy and…

Despite the great success of word embedding, sentence embedding remains a not-well-solved problem. In this paper, we present a supervised learning framework to exploit sentence embedding for the medical question answering task. The learning…

Computation and Language · Computer Science 2018-11-16 Yu Hao , Xien Liu , Ji Wu , Ping Lv

Diagnosis of a clinical condition is a challenging task, which often requires significant medical investigation. Previous work related to diagnostic inferencing problems mostly consider multivariate observational data (e.g. physiological…

Computation and Language · Computer Science 2017-01-05 Aaditya Prakash , Siyuan Zhao , Sadid A. Hasan , Vivek Datla , Kathy Lee , Ashequl Qadir , Joey Liu , Oladimeji Farri

Automatic representation learning of key entities in electronic health record (EHR) data is a critical step for healthcare informatics that turns heterogeneous medical records into structured and actionable information. Here we propose…

Machine Learning · Computer Science 2019-10-08 Tong Wu , Yunlong Wang , Yue Wang , Emily Zhao , Yilian Yuan , Zhi Yang