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We introduce and study methods for inferring and learning from correspondences among neurons. The approach enables alignment of data from distinct multiunit studies of nervous systems. We show that the methods for inferring correspondences…

Neurons and Cognition · Quantitative Biology 2015-01-28 Ashish Kapoor , E. Paxon Frady , Stefanie Jegelka , William B. Kristan , Eric Horvitz

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

Neurons and Cognition · Quantitative Biology 2017-03-03 Jannis Schuecker , Maximilian Schmidt , Sacha J. van Albada , Markus Diesmann , Moritz Helias

Performing more tasks in parallel is a typical feature of complex brains. These are characterized by the coexistence of excitatory and inhibitory synapses, whose percentage in mammals is measured to have a typical value of 20-30\%. Here we…

Neurons and Cognition · Quantitative Biology 2015-08-25 Vittorio Capano , Hans J. Herrmann , Lucilla de Arcangelis

How the information microscopically processed by individual neurons is integrated and used in organizing the behavior of an animal is a central question in neuroscience. The coherence of neuronal dynamics over different scales has been…

Disordered Systems and Neural Networks · Physics 2020-03-11 Takashi Hayakawa , Tomoki Fukai

We present a bipartite network model that captures intermediate stages of optimization by blending the Maximum Entropy approach with Optimal Transport. In this framework, the network's constraints define the total mass each node can supply…

Statistical Mechanics · Physics 2026-02-05 Lorenzo Buffa , Dario Mazzilli , Riccardo Piombo , Fabio Saracco , Giulio Cimini , Aurelio Patelli

Demystifying effective connectivity among neuronal populations has become the trend to understand the brain mechanisms of Parkinson's disease, schizophrenia, mild traumatic brain injury, and many other unlisted neurological diseases.…

Quantitative Methods · Quantitative Biology 2019-09-27 Po-Ya Hsu

This paper deals with the problem of inferring the signals and parameters that cause neural activity to occur. The ultimate challenge being to unveil brain's connectivity, here we focus on a microscopic vision of the problem, where single…

Computation · Statistics 2015-11-13 Pau Closas , Antoni Guillamon

Hawkes process provides an effective statistical framework for analyzing the time-dependent interaction of neuronal spiking activities. Although utilized in many real applications, the classic Hawkes process is incapable of modelling…

Machine Learning · Statistics 2021-02-23 Feng Zhou , Yixuan Zhang , Jun Zhu

We study the statistics of spike trains of simultaneously recorded grid cells in freely behaving rats. We evaluate pairwise correlations between these cells and, using a generalized linear model (kinetic Ising model), study their functional…

Neurons and Cognition · Quantitative Biology 2015-06-19 Benjamin Dunn , Maria Mørreaunet , Yasser Roudi

Maximum entropy principle (MEP) offers an effective and unbiased approach to inferring unknown probability distributions when faced with incomplete information, while neural networks provide the flexibility to learn complex distributions…

Machine Learning · Statistics 2024-12-04 Wuyue Yang , Liangrong Peng , Guojie Li , Liu Hong

I consider the problem of deriving couplings of a statistical model from measured correlations, a task which generalizes the well-known inverse Ising problem. After reminding that such problem can be mapped on the one of expressing the…

Statistical Mechanics · Physics 2013-10-09 Iacopo Mastromatteo

Understanding the relation between cortical neuronal network structure and neuronal activity is a fundamental unresolved question in neuroscience, with implications to our understanding of the mechanism by which neuronal networks evolve…

The availability of large-scale neuronal population datasets necessitates new methods to model population dynamics and extract interpretable, scientifically translatable insights. Existing deep learning methods often overlook the biological…

Neurons and Cognition · Quantitative Biology 2024-11-14 Parsa Delavari , Ipek Oruc , Timothy H Murphy

In this study, we analyzed the activity of monkey V1 neurons responding to grating stimuli of different orientations using inference methods for a time-dependent Ising model. The method provides optimal estimation of time-dependent neural…

Neurons and Cognition · Quantitative Biology 2018-07-25 Jimmy Gaudreault , Hideaki Shimazaki

Networks of spiking neurons with adaption have been shown to be able to reproduce a wide range of neural activities, including the emergent population bursting and spike synchrony that underpin brain disorders and normal function. Exact…

Neurons and Cognition · Quantitative Biology 2022-03-17 Liang Chen , Sue Ann Campbell

We study the dynamics of the processes in the small-world networks with a power-law degree distribution where every node is considered to be in one of the two available statuses. We present an algorithm for generation of such network and…

Statistical Mechanics · Physics 2019-07-19 Bahruz Gadjiev , Tatiana Progulova

A core challenge for the brain is to process information across various timescales. This could be achieved by a hierarchical organization of temporal processing through intrinsic mechanisms (e.g., recurrent coupling or adaptation), but…

Neurons and Cognition · Quantitative Biology 2024-01-18 Lucas Rudelt , Daniel González Marx , F. Paul Spitzner , Benjamin Cramer , Johannes Zierenberg , Viola Priesemann

Neural circuits must balance local connectivity constraints against the need for global integration. Here we introduce a minimal wiring rule motivated by synaptic crowding: as a neuron accumulates incoming connections, each additional…

Neurons and Cognition · Quantitative Biology 2026-03-23 Makoto Fukushima

We briefly review and highlight the consequences of rigorous and exact results obtained in \cite{cessac:10}, characterizing the statistics of spike trains in a network of leaky Integrate-and-Fire neurons, where time is discrete and where…

Adaptation and Self-Organizing Systems · Physics 2010-08-31 Bruno Cessac , Hassan Nasser , Juan-Carlos Vasquez

Although instantaneous interactions are unphysical, a large variety of maximum entropy statistical inference methods match the model-inferred and the empirically-measured equal-time correlation functions. Focusing on collective motion of…