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Deterministic optical manipulation of fluorescent nanodiamonds (FNDs) in fluids has emerged as an experimental challenge in multimodal biological imaging. Designing and developing nano-optical trapping strategies to serve this purpose is an…

The nitrogen-vacancy (NV) center in diamond exists in different charge states with distinct photoluminescence properties, which are sensitive to the nanoscale electrochemical environment. Hence, the NV charge state is emerging as a powerful…

Mesoscale and Nanoscale Physics · Physics 2026-05-12 Patrick Voorhoeve , Hiroshi Abe , Takeshi Ohshima , Qiang Sun , Anita Quigley , Rob Kapsa , Nikolai Dontschuk , Philipp Reineck

Fluorescent nanodiamonds (FNDs) have been exploited as sensitive quantum probes for nanoscale chemical and biological sensing applications, with the majority of demonstrations to date relying on the detection of single FNDs. This places…

Owing to the unique electronic spin properties, the nitrogen-vacancy (NV) centers hosted in diamond have emerged as a powerful quantum sensor for various physical parameters and biological species. In this work, a miniature optical-fiber…

Understanding and controlling fluorescent nanodiamonds (FNDs) with optically read qubits is a key focus of research, as they show high potential for detecting electric and magnetic fields, temperature, and other physico-chemical quantities…

Nitrogen vacancy (NV) color centers in diamond have emerged as highly versatile optical emitters that exhibit room temperature spin properties. These characteristics make NV centers ideal for magnetometry, which plays an important role in…

Quantum Physics · Physics 2017-07-26 Kangmook Lim , Chad Ropp , Benjamin Shapiro , Jacob M. Taylor , Edo Waks

Nanodiamonds containing nitrogen-vacancy (NV) centers offer a versatile platform for sensing applications spanning from nanomagnetism to in-vivo monitoring of cellular processes. In many cases, however, weak optical signals and poor…

Quantum Physics · Physics 2018-04-30 David A. Hopper , Richard R. Grote , Samuel M. Parks , Lee C. Bassett

Optically accessible spin-active nanomaterials are promising as quantum nanosensors for probing biological samples. However, achieving bioimaging-level brightness and high-quality spin properties for these materials is challenging and…

Understanding the behavior of confined water at liquid-solid interfaces is central to numerous physical, chemical, and biological processes, yet remains experimentally challenging. Here, we utilize shallow nitrogen-vacancy (NV) centers in…

The nitrogen-vacancy (NV) centers in nanodiamonds can be utilized as low-cost, highly versatile quantum sensors for studying surface properties in condensed matter physics through the application of relaxometry protocols. For such…

Mesoscale and Nanoscale Physics · Physics 2025-09-03 Izidor Benedičič , Yuri Tanuma , Žiga Gosar , Bastien Anézo , Mariusz Mrózek , Adam Wojciechowski , Denis Arčon

Spin relaxometry using fluorescent nanodiamonds (FNDs) has been applied successfully to sense numerous paramagnetic target molecules such as free radicals and metalloproteins. However, despite their high sensitivity, T1 spin relaxation…

Mesoscale and Nanoscale Physics · Physics 2026-02-23 Trent Ralph , Erin S. Grant , Lianne Lay , Sepehr Ahmadi , David A. Simpson

Sensitive probing of temperature variations on nanometer scales represents an outstanding challenge in many areas of modern science and technology. In particular, a thermometer capable of sub-degree temperature resolution as well as…

Quantum Physics · Physics 2013-08-06 G. Kucsko , P. C. Maurer , N. Y. Yao , M. Kubo , H. J. Noh , P. K. Lo , H. Park , M. D. Lukin

Biosensing based on optically trapped fluorescent nanodiamonds potentially allows to resolve biochemical processes inside living cells at a desired intracellular location. Towards this goal, we investigate near infrared (NIR) laser…

Atomic-scale magnetic field sensors based on nitrogen vacancy (NV) defects in diamonds are an exciting platform for nanoscale nuclear magnetic resonance (NMR) spectroscopy. The detection of NMR signals from a few zeptoliters to single…

Biocompatible nanoscale probes for sensitive detection of paramagnetic species and molecules associated with their (bio)chemical transformations would provide a desirable tool for a better understanding of cellular redox processes. Here, we…

In this article we explore the requirements for enabling high quality optically detected magnetic resonance (ODMR) spectroscopy in a conventional gradient force optical tweezers using nanodiamonds containing nitrogen-vacancy (NV$^{-}$)…

Optics · Physics 2021-01-25 L. W. Russell , E. C. Dossetor , A. A. Wood , D. A. Simpson , P. J. Reece

The negatively-charged nitrogen-vacancy (NV) center in diamond is at the frontier of quantum nano-metrology and bio-sensing. Recent attention has focused on the application of high-sensitivity thermometry using the spin resonances of NV…

Quantum Physics · Physics 2015-02-26 Taras Plakhotnik , Marcus W. Doherty , Jared H. Cole , Robert Chapman , Neil B. Manson

In many chemical reactions, short-lived radical intermediates play a crucial role, while detecting such short-lived species in-situ remains challenging. The optically readable electronic spin of nitrogen-vacancy (NV) centers in diamond is a…

Mesoscale and Nanoscale Physics · Physics 2026-04-22 Emma Herbst , Sebastian Westrich , Alena Erlenbach , Jonas Gutsche , Maria Wächtler , Elke Neu

Enzymes are cellular protein machines using a variety of conformational changes to power fast biochemical catalysis. Our goal is to exploit the single-spin properties of the luminescent NV (nitrogen-vacancy) center in nanodiamonds to reveal…

Quantitative Methods · Quantitative Biology 2024-01-25 Ivan Perez , Anke Krueger , Joerg Wrachtrup , Fedor Jelezko , Michael Börsch

Nitrogen-vacancy (NV) centers in nanodiamonds are excellent nanoscale sensors for measuring parameters such as temperature, magnetic field, and viscosity in complex fluidic environments, including living cells. However, the rapid motion of…

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