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We present a new semi-external algorithm that builds the Burrows--Wheeler transform variant of Bauer et al. (a.k.a., BCR BWT) in linear expected time. Our method uses compression techniques to reduce computational costs when the input is…

Data Structures and Algorithms · Computer Science 2023-08-15 Diego Díaz-Domínguez , Gonzalo Navarro

The Burrows-Wheeler-Transform (BWT) is a reversible string transformation which plays a central role in text compression and is fundamental in many modern bioinformatics applications. The BWT is a permutation of the characters, which is in…

Data Structures and Algorithms · Computer Science 2021-03-15 Sara Giuliani , Zsuzsanna Lipták , Francesco Masillo , Romeo Rizzi

The Burrows-Wheeler Transform (BWT) serves as the basis for many important sequence indexes. On very large datasets (e.g. genomic databases), classical BWT construction algorithms are often infeasible because they usually need to have the…

Data Structures and Algorithms · Computer Science 2025-09-24 Jannik Olbrich

The Burrows-Wheeler Transform (BWT) is often taught in undergraduate courses on algorithmic bioinformatics, because it underlies the FM-index and thus important tools such as Bowtie and BWA. Its admirers consider the BWT a thing of beauty…

Data Structures and Algorithms · Computer Science 2022-08-23 Travis Gagie , Giovanni Manzini , Marinella Sciortino

The boom of genomic sequencing makes compression of set of sequences inescapable. This underlies the need for multi-string indexing data structures that helps compressing the data. The most prominent example of such data structures is the…

Data Structures and Algorithms · Computer Science 2021-11-18 Bastien Cazaux , Eric Rivals

Compressed suffix arrays (CSAs) index large repetitive collections and are key in many text applications. The r-index and its derivatives combine the run-length Burrows-Wheeler Transform (BWT) with suffix array sampling to achieve space…

Data Structures and Algorithms · Computer Science 2026-02-20 Diego Díaz-Domínguez , Veli Mäkinen

We propose algorithms that, given the input string of length $n$ over integer alphabet of size $\sigma$, construct the Burrows-Wheeler transform (BWT), the permuted longest-common-prefix (PLCP) array, and the LZ77 parsing in…

Data Structures and Algorithms · Computer Science 2020-12-09 Dominik Kempa

In order to avoid the reference bias introduced by mapping reads to a reference genome, bioinformaticians are investigating reference-free methods for analyzing sequenced genomes. With large projects sequencing thousands of individuals,…

Data Structures and Algorithms · Computer Science 2016-01-15 Jouni Sirén

One of the most well-known variants of the Burrows-Wheeler transform (BWT) [Burrows and Wheeler, 1994] is the bijective BWT (BBWT) [Gil and Scott, arXiv 2012], which applies the extended BWT (EBWT) [Mantaci et al., TCS 2007] to the multiset…

Data Structures and Algorithms · Computer Science 2020-04-28 Dominik Köppl , Daiki Hashimoto , Diptarama Hendrian , Ayumi Shinohara

The Burrows-Wheeler Transform (BWT) of a string is an invertible permutation of the string, which can be used for data compression and compact indexes for string pattern matching. Ganguly et al. [SODA, 2017] introduced the parameterized BWT…

Data Structures and Algorithms · Computer Science 2025-05-12 Shogen Kawanami , Kento Iseri , Tomohiro I

Indexing highly repetitive strings (i.e., strings with many repetitions) for fast queries has become a central research topic in string processing, because it has a wide variety of applications in bioinformatics and natural language…

Data Structures and Algorithms · Computer Science 2021-04-19 Takaaki Nishimoto , Yasuo Tabei

In recent years, the focus of bioinformatics research has moved from individual sequences to collections of sequences. Given the fundamental role of the Burrows-Wheeler Transform (BWT) in string processing, a number of dedicated tools have…

Data Structures and Algorithms · Computer Science 2025-05-28 Davide Cenzato , Zsuzsanna Lipták

Constructing the Burrows-Wheeler transform (BWT) for long strings poses significant challenges regarding construction time and memory usage. We use a prefix of the suffix array to partition a long string into shorter substrings, thereby…

Data Structures and Algorithms · Computer Science 2025-05-15 Enno Adler , Stefan Böttcher , Rita Hartel

Indexing of very large collections of strings such as those produced by the widespread sequencing technologies, heavily relies on multi-string generalizations of the Burrows-Wheeler Transform (BWT), and for this problem various in-memory…

Data Structures and Algorithms · Computer Science 2016-07-29 Paola Bonizzoni , Gianluca Della Vedova , Serena Nicosia , Marco Previtali , Raffaella Rizzi

The Lempel-Ziv factorization (LZ77) and the Run-Length encoded Burrows-Wheeler Transform (RLBWT) are two important tools in text compression and indexing, being their sizes $z$ and $r$ closely related to the amount of text…

Data Structures and Algorithms · Computer Science 2017-02-07 Alberto Policriti , Nicola Prezza

Due to the exponential growth of genomic data, constructing dedicated data structures has become the principal bottleneck in common bioinformatics applications. In particular, the Burrows-Wheeler Transform (BWT) is the basis of some of the…

Data Structures and Algorithms · Computer Science 2023-05-15 Francesco Masillo

The Positional Burrows--Wheeler Transform (PBWT) is a data structure designed for efficiently representing and querying large collections of sequences, such as haplotype panels in genomics. Forward and backward stepping operations --…

Data Structures and Algorithms · Computer Science 2026-02-17 Paola Bonizzoni , Davide Cozzi , Younan Gao

We investigate properties of the bijective Burrows-Wheeler transform (BBWT). We show that for any string $w$, a bidirectional macro scheme of size $O(r_B)$ can be induced from the BBWT of $w$, where $r_B$ is the number of maximal character…

Data Structures and Algorithms · Computer Science 2024-08-20 Golnaz Badkobeh , Hideo Bannai , Dominik Köppl

The Burrows-Wheeler transform (BWT) is integral to the FM-index, which is used extensively in text compression, indexing, pattern search, and bioinformatic problems as de novo assembly and read alignment. Thus, efficient construction of the…

Data Structures and Algorithms · Computer Science 2025-02-04 Enno Adler , Stefan Böttcher , Rita Hartel , Cederic Alexander Steininger

The Burrows-Wheeler transform (BWT) is used by the bzip2 family of compressors. In this paper, we present a hardware architecture that implements an inplace algorithm to compute the BWT. Our design does not have explicit storage for the…

Signal Processing · Electrical Eng. & Systems 2022-09-07 Kleber Stangherlin , Andrew Kennings