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The morphology of glands has been used routinely by pathologists to assess the malignancy degree of adenocarcinomas. Accurate segmentation of glands from histology images is a crucial step to obtain reliable morphological statistics for…

Computer Vision and Pattern Recognition · Computer Science 2016-04-12 Hao Chen , Xiaojuan Qi , Lequan Yu , Pheng-Ann Heng

Histology method is vital in the diagnosis and prognosis of cancers and many other diseases. For the analysis of histopathological images, we need to detect and segment all gland structures. These images are very challenging, and the task…

Image and Video Processing · Electrical Eng. & Systems 2019-11-05 Safiye Rezaei , Ali Emami , Nader Karimi , Shadrokh Samavi

Segmentation of histopathology sections is an ubiquitous requirement in digital pathology and due to the large variability of biological tissue, machine learning techniques have shown superior performance over standard image processing…

Computer Vision and Pattern Recognition · Computer Science 2017-10-11 Philipp Kainz , Michael Pfeiffer , Martin Urschler

Histopathology images contain essential information for medical diagnosis and prognosis of cancerous disease. Segmentation of glands in histopathology images is a primary step for analysis and diagnosis of an unhealthy patient. Due to the…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Safiyeh Rezaei , Ali Emami , Hamidreza Zarrabi , Shima Rafiei , Kayvan Najarian , Nader Karimi , Shadrokh Samavi , S. M. Reza Soroushmehr

We trained and applied an encoder-decoder model to semantically segment breast biopsy images into biologically meaningful tissue labels. Since conventional encoder-decoder networks cannot be applied directly on large biopsy images and the…

Computer Vision and Pattern Recognition · Computer Science 2017-10-12 Sachin Mehta , Ezgi Mercan , Jamen Bartlett , Donald Weaver , Joann Elmore , Linda Shapiro

Objective: A new image instance segmentation method is proposed to segment individual glands (instances) in colon histology images. This process is challenging since the glands not only need to be segmented from a complex background, they…

Computer Vision and Pattern Recognition · Computer Science 2017-11-27 Yan Xu , Yang Li , Yipei Wang , Mingyuan Liu , Yubo Fan , Maode Lai , Eric I-Chao Chang

Gland segmentation is a critical step to quantitatively assess the morphology of glands in histopathology image analysis. However, it is challenging to separate densely clustered glands accurately. Existing deep learning-based approaches…

Image and Video Processing · Electrical Eng. & Systems 2021-10-28 Haotian Wang , Min Xian , Aleksandar Vakanski

In this paper, we propose a new image instance segmentation method that segments individual glands (instances) in colon histology images. This is a task called instance segmentation that has recently become increasingly important. The…

Computer Vision and Pattern Recognition · Computer Science 2016-07-20 Yan Xu , Yang Li , Mingyuan Liu , Yipei Wang , Yubo Fan , Maode Lai , Eric I-Chao Chang

Automatic segmentation of brain glioma from multimodal MRI scans plays a key role in clinical trials and practice. Unfortunately, manual segmentation is very challenging, time-consuming, costly, and often inaccurate despite human expertise…

Image and Video Processing · Electrical Eng. & Systems 2020-12-08 Minh H. Vu , Tufve Nyholm , Tommy Löfstedt

Cancer grade is a critical clinical criterion that can be used to determine the degree of cancer malignancy. Revealing the condition of the glands, a precise gland segmentation can assist in a more effective cancer grade classification. In…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Yijie Zhu , Shan E Ahmed Raza

Accurate detection and segmentation of glomeruli in kidney tissue are essential for diagnostic applications. Traditional deep learning methods primarily rely on semantic segmentation, which often fails to precisely delineate adjacent…

Tissues and Organs · Quantitative Biology 2026-04-17 Behnaz Elhaminia , Catherine King , Jiaqi Lv , Lorraine Harper , Paul Moss , Owen Cain , Dimitrios Chanouzas , Shan E Ahmed Raza

Designing deep learning algorithms for gland segmentation is crucial for automatic cancer diagnosis and prognosis, yet the expensive annotation cost hinders the development and application of this technology. In this paper, we make a first…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Qixiang Zhang , Yi Li , Cheng Xue , Xiaomeng Li

Grading of cancer is important to know the extent of its spread. Prior to grading, segmentation of glandular structures is important. Manual segmentation is a time consuming process and is subject to observer bias. Hence, an automated…

Computer Vision and Pattern Recognition · Computer Science 2017-08-16 Rohith AP , Salman S. Khan , Kumar Anubhav , Angshuman Paul

Automated medical image segmentation plays a key role in quantitative research and diagnostics. Convolutional neural networks based on the U-Net architecture are the state-of-the-art. A key disadvantage is the hard-coding of the receptive…

Image and Video Processing · Electrical Eng. & Systems 2019-10-24 Hans Pinckaers , Geert Litjens

In this paper, we propose a new image instance segmentation method that segments individual glands (instances) in colon histology images. This is a task called instance segmentation that has recently become increasingly important. The…

Computer Vision and Pattern Recognition · Computer Science 2016-07-15 Yan Xu , Yang Li , Mingyuan Liu , Yipei Wang , Maode Lai , Eric I-Chao Chang

Breast ultrasound imaging is a valuable tool for early breast cancer detection, but automated tumor segmentation is challenging due to inherent noise, variations in scale of lesions, and fuzzy boundaries. To address these challenges, we…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Muhammad Azeem Aslam , Asim Naveed , Nisar Ahmed

Developing an AI-assisted gland segmentation method from histology images is critical for automatic cancer diagnosis and prognosis; however, the high cost of pixel-level annotations hinders its applications to broader diseases. Existing…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Yi Li , Yiduo Yu , Yiwen Zou , Tianqi Xiang , Xiaomeng Li

Segmenting biomarkers in medical images is crucial for various biotech applications. Despite advances, Transformer and CNN based methods often struggle with variations in staining and morphology, limiting feature extraction. In medical…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Saad Wazir , Daeyoung Kim

Brain tumor segmentation is a challenging problem in medical image analysis. The endpoint is to generate the salient masks that accurately identify brain tumor regions in an fMRI screening. In this paper, we propose a novel attention gate…

Image and Video Processing · Electrical Eng. & Systems 2021-07-08 Tim Cvetko

Kidney structures segmentation is a crucial yet challenging task in the computer-aided diagnosis of surgery-based renal cancer. Although numerous deep learning models have achieved remarkable success in many medical image segmentation…

Image and Video Processing · Electrical Eng. & Systems 2022-08-30 Shishuai Hu , Yiwen Ye , Zehui Liao , Yong Xia
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