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Monitoring of cardiovascular activity is highly desired and can enable novel applications in diagnosing potential cardiovascular diseases and maintaining an individual's well-being. Currently, such vital signs are measured using intrusive…
Background: Chronic obstructive pulmonary disease (COPD) is one of the most prevalent and dangerous pulmonary diseases in the world. It is forecasted that COPD will be the third deadly disease in the future. Therefore, developing…
Imaging fluorescent disease biomarkers in tissues and skin is a non-invasive method to screen for health conditions. We report an automated process that combines intraoral fluorescent porphyrin biomarker imaging, clinical examinations and…
Age prediction from medical images or other health-related non-imaging data is an important approach to data-driven aging research, providing knowledge of how much information a specific tissue or organ carries about the chronological age…
PURPOSE: To develop an automated algorithm allowing extraction of quantitative corneal transparency parameters from clinical spectral-domain OCT images. To establish a representative dataset of normative transparency values from healthy…
One of the symptoms of Parkinson's disease (PD) is hypomimia or reduced facial expressions. In this paper, we present a digital biomarker for PD that utilizes the study of micro-expressions. We analyzed the facial action units (AU) from…
Capillaries are the smallest vessels in the body responsible for delivering oxygen and nutrients to surrounding cells. Various life-threatening diseases are known to alter the density of healthy capillaries and the flow velocity of…
The choroid, a highly vascular layer behind the retina, is an extension of the central nervous system and has parallels with the renal cortex, with blood flow far exceeding that of the brain and kidney. Thus, there has been growing interest…
Motion-related artifacts are inevitable in Magnetic Resonance Imaging (MRI) and can bias automated neuroanatomical metrics such as cortical thickness. These biases can interfere with statistical analysis which is a major concern as motion…
We study the problem of facial analysis in videos. We propose a novel weakly supervised learning method that models the video event (expression, pain etc.) as a sequence of automatically mined, discriminative sub-events (eg. onset and…
Purpose: Recently the authors presented a technique that allows corneal thickness measurements along any meridian from optical sections obtained using a rotary scanning system. This paper presents 3-D mapping of the corneal thickness and…
We investigated the feasibility and advantages of using non-contrast CT calcium score (CTCS) images to assess pericoronary adipose tissue (PCAT) and its association with major adverse cardiovascular events (MACE). PCAT features from…
This paper presents a comparative evaluation of methods for remote heart rate estimation using face videos, i.e., given a video sequence of the face as input, methods to process it to obtain a robust estimation of the subjects heart rate at…
Currently, diagnosis of skin diseases is based primarily on visual pattern recognition skills and expertise of the physician observing the lesion. Even though dermatologists are trained to recognize patterns of morphology, it is still a…
Dry Eye Disease (DED) is one of the most common ocular diseases: over five percent of US adults suffer from DED. Tear film instability is a known factor for DED, and is thought to be regulated in large part by the thin lipid layer that…
Peripheral blood oxygen saturation (SpO2), an indicator of oxygen levels in the blood, is one of the most important physiological parameters. Although SpO2 is usually measured using a pulse oximeter, non-contact SpO2 estimation methods from…
Objective: This study aims to evaluate the functional significance of coronary stenosis by analyzing low-level radiomic features of the pericoronary adipose tissue (PCAT) surrounding the lesions, which are indicative of its inflammation…
Social Anxiety Disorder (SAD) significantly impacts individuals' daily lives and relationships. The conventional methods for SAD detection involve physical consultations and self-reported questionnaires, but they have limitations such as…
Orofacial deficits are common in people with Parkinson's disease (PD) and their evolution might represent an important biomarker of disease progression. We are developing an automated system for assessment of orofacial function in PD that…
We present an efficient and accessible PD screening method by leveraging AI-driven models enabled by the largest video dataset of facial expressions from 1,059 unique participants. This dataset includes 256 individuals with PD, 165…