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We consider a generalization of the classical logistic growth model introducing more than one inflection point. The growth, called multi-sigmoidal, is firstly analyzed from a deterministic point of view in order to obtain the main…

Populations and Evolution · Quantitative Biology 2024-01-31 Antonio Di Crescenzo , Paola Paraggio , Patricia Román-Román , Francisco Torres-Ruiz

This research aims to estimate three parameters in a stochastic generalized logistic differential equation. We assume the intrinsic growth rate and shape parameters are constant but unknown. To estimate these two parameters, we use the…

The maximum likelihood approach is adapted to the problem of estimation of drift and diffusion functions of stochastic processes from measured time series. We reconcile a previously devised iterative procedure [Kleinhans et al., Physics…

Data Analysis, Statistics and Probability · Physics 2009-11-13 D. Kleinhans , R. Friedrich

In this paper, we provide a multiscale perspective on the problem of maximum marginal likelihood estimation. We consider and analyse a diffusion-based maximum marginal likelihood estimation scheme using ideas from multiscale dynamics. Our…

Computation · Statistics 2024-06-11 O. Deniz Akyildiz , Michela Ottobre , Iain Souttar

Filtering and parameter estimation under partial information for multiscale problems is studied in this paper. After proving mean square convergence of the nonlinear filter to a filter of reduced dimension, we establish that the conditional…

Probability · Mathematics 2014-09-09 Andrew Papanicolaou , Konstantinos Spiliopoulos

A stochastic diffusion process, whose mean function is a hyperbolastic curve of type I, is presented. Themain characteristics of the process are studied and the problem of maximum likelihood estimation forthe parameters of the process is…

Methodology · Statistics 2024-02-07 Antonio Barrera , Patricia Román-Román , Francisco Torres-Ruiz

The behaviour of many dynamic real phenomena shows different phases, with each one following a sigmoidal type pattern. This requires studying sigmoidal curves with more than one inflection point. In this work, a diffusion process is…

Statistics Theory · Mathematics 2024-01-31 Patricia Román-Román , Juan José Serrano-Pérez , Francisco Torres-Ruiz

We study the problem of parameter estimation using maximum likelihood for fast/slow systems of stochastic differential equations. Our aim is to shed light on the problem of model/data mismatch at small scales. We consider two classes of…

Statistics Theory · Mathematics 2008-06-20 A. Papavasiliou , G. A. Pavliotis , A. M. Stuart

Logistic regression with unknown sizes has many important applications in biological and medical sciences. All models about this problem in the literature are parametric ones. A semiparametric regression model is proposed. This model…

Statistics Theory · Mathematics 2007-06-13 Wei Zhang

This paper studies an approximation method for the log-likelihood function of a nonlinear diffusion process using the bridge of the diffusion. The main result (Theorem \refthm:approx) shows that this approximation converges uniformly to the…

Statistics Theory · Mathematics 2010-01-11 Aleksandar Mijatović , Paul Schneider

We compute profile likelihoods for a stochastic model of diffusive transport motivated by experimental observations of heat conduction in layered skin tissues. This process is modelled as a random walk in a layered one-dimensional material,…

A free boundary diffusive logistic model finds application in many different fields from biological invasion to wildfire propagation. However, many of these processes show a random nature and contain uncertainties in the parameters. In this…

Numerical Analysis · Mathematics 2025-01-17 M. -C. Casabán , R. Company , V. N. Egorova , L. Jódar

The controlled branching process is a generalization of the classical Bienaym\'e-Galton-Watson branching process. It is a useful model for describing the evolution of populations in which the population size at each generation needs to be…

Statistics Theory · Mathematics 2015-02-09 M. Gonzalez , C. Minuesa , I. del Puerto

Binomial data with unknown sizes often appear in biological and medical sciences and are usually overdispersed. All previous methods used parametric models and only considered overdispersion due to the variation of sizes. The proposed…

Statistics Theory · Mathematics 2007-06-13 Wei Zhang

In this work, we consider a manufactory process which can be described by a multiple-instance logistic regression model. In order to compute the maximum likelihood estimation of the unknown coefficient, an expectation-maximization algorithm…

We revisit the problem of estimating the parameters of a partially observed diffusion process, consisting of a hidden state process and an observed process, with a continuous time parameter. The estimation is to be done online, i.e. the…

Optimization and Control · Mathematics 2018-10-16 Simone Carlo Surace , Jean-Pascal Pfister

Single-molecule localization microscopy allows practitioners to locate and track labeled molecules in biological systems. When extracting diffusion coefficients from the resulting trajectories, it is common practice to perform a linear fit…

Biological Physics · Physics 2024-06-19 Jakob Tómas Bullerjahn , Gerhard Hummer

We consider the problem of frequency estimation by observations of the periodic diffusion process possesing ergodic properties in two different situations. The first one corresponds to continuously differentiable with respect to parameter…

Statistics Theory · Mathematics 2020-03-30 Reinhard Höpfner , Yury A Kutoyants

Binomial data with unknown sizes often appear in biological and medical sciences. The previous methods either use the Poisson approximation or the quasi-likelihood approach. A full likelihood approach is proposed by treating unknown sizes…

Statistics Theory · Mathematics 2007-06-13 Wei Zhang

We propose a new statistical observation scheme of diffusion processes named convolutional observation, where it is possible to deal with smoother observation than ordinary diffusion processes by considering convolution of diffusion…

Statistics Theory · Mathematics 2020-10-28 Shogo H Nakakita , Masayuki Uchida
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