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Motivated by applications in DNA storage, we study a setting in which strings are affected by tandem-duplication errors. In particular, we look at two settings: disjoint tandem-duplication errors, and equal-length tandem-duplication errors.…

Information Theory · Computer Science 2024-01-10 Wenjun Yu , Moshe Schwartz

This work presents a theoretical analysis of the probability of successfully retrieving data encoded with MDS codes (e.g., Reed-Solomon codes) in DNA storage systems. We study this probability under independent and identically distributed…

Information Theory · Computer Science 2026-05-08 Serge Kas Hanna

Noisy shuffling channels capture the main characteristics of DNA storage systems where distinct segments of data are received out of order, after being corrupted by substitution errors. For realistic schemes with short-length segments,…

Information Theory · Computer Science 2024-10-07 Javad Haghighat , Tolga M. Duman

We propose a novel coding scheme for DNA-based storage systems, called the shift-interleave (SI) coding, designed to correct insertion, deletion, and substitution (IDS) errors, as well as sequence losses. The SI coding scheme employs…

Information Theory · Computer Science 2024-01-29 Ryo Shibata , Haruhiko Kaneko

In computational molecular biology, gene regulatory binding sites prediction in whole genome remains a challenge for the researchers. Now a days, the genome wide regulatory binding site prediction tools required either direct pattern…

Genomics · Quantitative Biology 2010-02-06 Chandra Prakash Singh , Feroz Khan , Sanjay Kumar Singh , Durg Singh Chauhan

We consider the problem of coding for the substring channel, in which information strings are observed only through their (multisets of) substrings. Due to existing DNA sequencing techniques and applications in DNA-based storage systems,…

Information Theory · Computer Science 2024-03-27 Yonatan Yehezkeally , Nikita Polyanskii

In order to overcome the limitations imposed by DNA barcoding when multiplexing a large number of samples in the current generation of high-throughput sequencing instruments, we have recently proposed a new protocol that leverages advances…

Quantitative Methods · Quantitative Biology 2013-08-02 Denisa Duma , Mary Wootters , Anna C. Gilbert , Hung Q. Ngo , Atri Rudra , Matthew Alpert , Timothy J. Close , Gianfranco Ciardo , Stefano Lonardi

The macromolecules that encode and translate information in living systems, DNA and RNA, exhibit distinctive structural asymmetries, including homochirality or mirror image asymmetry and $3' - 5'$ directionality, that are invariant across…

Biomolecules · Quantitative Biology 2017-03-10 Hemachander Subramanian , Robert A. Gatenby

The DNA cryptography is a new and very promising direction in cryptography research. DNA can be used in cryptography for storing and transmitting the information, as well as for computation. Although in its primitive stage, DNA cryptography…

Cryptography and Security · Computer Science 2012-03-07 Kang Ning

This paper presents and analyzes a novel concatenated coding scheme for enabling error resilience in two distributed storage settings: one being storage using existing regenerating codes and the second being storage using locally repairable…

Information Theory · Computer Science 2013-12-12 Natalia Silberstein , Ankit Singh Rawat , Sriram Vishwanath

Based on the theoretical neuroscience, G. Cotardo and A. Ravagnavi in \cite{CR} introduced a kind of asymmetric binary codes called combinatorial neural codes (CN codes for short), with a "matched metric" $\delta_{r}$ called asymmetric…

Information Theory · Computer Science 2021-12-16 Aixian Zhang , Xiaoyan Jin , Keqin Feng

DNA storage has matured from concept to practical stage, yet its integration with neural compression pipelines remains inefficient. Early DNA encoders applied redundancy-heavy constraint layers atop raw binary data - workable but primitive.…

Machine Learning · Computer Science 2026-02-09 Cihan Ruan , Lebin Zhou , Rongduo Han , Linyi Han , Bingqing Zhao , Chenchen Zhu , Wei Jiang , Wei Wang , Nam Ling

DNA based storage systems received attention by many researchers. This includes archival and re-writable random access DNA based storage systems. In this work, we have developed an efficient technique to encode the data into DNA sequence by…

Information Theory · Computer Science 2016-04-25 Dixita Limbachiya , Vijay Dhameliya , Madhav Khakhar , Manish K Gupta

The strongly correlated systems we use to realise quantum error-correcting codes may give rise to high-weight, problematic errors. Encouragingly, we can expect local quantum error-correcting codes with no string-like logical operators $-$…

Quantum Physics · Physics 2021-07-14 Georgia M. Nixon , Benjamin J. Brown

The article demonstrates a technique for fabricating a structure with the inclusion of suspended DNA threads and manipulating them using composite nanotweezers with shape memory effect. This technique could be suitable for stretching of…

Due to the redundant nature of DNA synthesis and sequencing technologies, a basic model for a DNA storage system is a multi-draw "shuffling-sampling" channel. In this model, a random number of noisy copies of each sequence is observed at…

Information Theory · Computer Science 2021-12-06 Kel Levick , Reinhard Heckel , Ilan Shomorony

Two concatenated coding schemes based on fixed-rate Raptor codes are proposed for error control in NAND flash memory. One is geared for off-line recovery of uncorrectable pages and the other is designed for page error correction during the…

Information Theory · Computer Science 2013-12-23 Geunyeong Yu , Jaekyun Moon

The simplest possible informational heteropolymer requires only a two-letter alphabet to be able to store information. The evolutionary choice of four monomers in the informational biomolecules RNA/DNA or their progenitors is intriguing,…

Genomics · Quantitative Biology 2022-11-17 Hemachander Subramanian

Motivated by communication channels in which the transmitted sequences are subject to random permutations, as well as by certain DNA storage systems, we study the error control problem in settings where the information is stored/transmitted…

Information Theory · Computer Science 2020-08-13 Mladen Kovačević , Vincent Y. F. Tan

In recent years, the emergence of DNA storage systems has led to a widespread focus on the research of codes correcting insertions, deletions, and classic substitutions. During the initial investigation, Levenshtein discovered the VT codes…

Information Theory · Computer Science 2024-01-23 Yuhang Pi , Zhifang Zhang
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