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Many biological studies involve inferring the evolutionary history of a sample of individuals from a large population and interpreting the reconstructed tree. Such an ascertained tree typically represents only a small part of a…

Populations and Evolution · Quantitative Biology 2024-08-13 Michael Celentano , William S. DeWitt , Sebastian Prillo , Yun S. Song

Finding an effective medical treatment often requires a search by trial and error. Making this search more efficient by minimizing the number of unnecessary trials could lower both costs and patient suffering. We formalize this problem as…

Machine Learning · Computer Science 2021-02-18 Samuel Håkansson , Viktor Lindblom , Omer Gottesman , Fredrik D. Johansson

Multi-target regression is useful in a plethora of applications. Although random forest models perform well in these tasks, they are often difficult to interpret. Interpretability is crucial in machine learning, especially when it can…

Machine Learning · Computer Science 2023-03-30 Avraam Bardos , Nikolaos Mylonas , Ioannis Mollas , Grigorios Tsoumakas

Survival analysis of right censored data arises often in many areas of research including medical research. Effect of covariates (and their interactions) on survival distribution can be studied through existing methods which requires to…

Methodology · Statistics 2021-08-11 Madan Gopal Kundu , Samiran Ghosh

Decision tree models, including random forests and gradient-boosted decision trees, are widely used in machine learning due to their high predictive performance. However, their complex structures often make them difficult to interpret,…

Artificial Intelligence · Computer Science 2026-01-08 Akihiro Takemura , Masayuki Otani , Katsumi Inoue

Tree methods (recursive partitioning) are a popular class of nonparametric methods for analyzing data. One extension of the basic tree methodology is the survival tree, which applies recursive partitioning to censored survival data. There…

Methodology · Statistics 2017-03-01 Wei Fu , Jeffrey S. Simonoff

We introduce random survival forests, a random forests method for the analysis of right-censored survival data. New survival splitting rules for growing survival trees are introduced, as is a new missing data algorithm for imputing missing…

Applications · Statistics 2008-11-12 Hemant Ishwaran , Udaya B. Kogalur , Eugene H. Blackstone , Michael S. Lauer

As a multitude of capable machine learning (ML) models become widely available in forms such as open-source software and public APIs, central questions remain regarding their use in real-world applications, especially in high-stakes…

Machine Learning · Computer Science 2024-06-03 Dimitris Bertsimas , Matthew Peroni

Security risk management can be applied on well-defined or existing systems; in this case, the objective is to identify existing vulnerabilities, assess the risks and provide for the adequate countermeasures. Security risk management can…

Cryptography and Security · Computer Science 2014-04-09 Stéphane Paul

Decision trees are interpretable models that are well-suited to non-linear learning problems. Much work has been done on extending decision tree learning algorithms with differential privacy, a system that guarantees the privacy of samples…

Machine Learning · Computer Science 2023-10-13 Daniël Vos , Jelle Vos , Tianyu Li , Zekeriya Erkin , Sicco Verwer

This paper is concerned with the approximation of high-dimensional functions in a statistical learning setting, by empirical risk minimization over model classes of functions in tree-based tensor format. These are particular classes of…

Machine Learning · Statistics 2019-01-15 Erwan Grelier , Anthony Nouy , Mathilde Chevreuil

Deep Learning based models are currently dominating most state-of-the-art solutions for disease prediction. Existing works employ RNNs along with multiple levels of attention mechanisms to provide interpretability. These deep learning…

Machine Learning · Statistics 2022-06-01 Subhadip Maji , Raghav Bali , Sree Harsha Ankem , Kishore V Ayyadevara

Survival analysis is a widely-used technique for analyzing time-to-event data in the presence of censoring. In recent years, numerous survival analysis methods have emerged which scale to large datasets and relax traditional assumptions…

Machine Learning · Computer Science 2023-11-06 Mert Ketenci , Shreyas Bhave , Noémie Elhadad , Adler Perotte

The rise of machine learning methods on heavily resource constrained devices requires not only the choice of a suitable model architecture for the target platform, but also the optimization of the chosen model with regard to execution time…

Machine Learning · Computer Science 2024-06-19 Lena Schmid , Daniel Biebert , Christian Hakert , Kuan-Hsun Chen , Michel Lang , Markus Pauly , Jian-Jia Chen

Nowadays new technologies, and especially artificial intelligence, are more and more established in our society. Big data analysis and machine learning, two sub-fields of artificial intelligence, are at the core of many recent breakthroughs…

Machine Learning · Statistics 2021-06-22 Antonio Sutera

Short spanning trees subject to additional constraints are important building blocks in various approximation algorithms. Especially in the context of the Traveling Salesman Problem (TSP), new techniques for finding spanning trees with…

Data Structures and Algorithms · Computer Science 2023-09-13 Martin Nägele , Rico Zenklusen

In many modern applications, including analysis of gene expression and text documents, the data are noisy, high-dimensional, and unordered--with no particular meaning to the given order of the variables. Yet, successful learning is often…

Methodology · Statistics 2008-07-25 Ann B. Lee , Boaz Nadler , Larry Wasserman

Identifying and making statistical inferences on differential treatment effects (commonly known as subgroup analysis in clinical research) is central to precision health. Subgroup analysis allows practitioners to pinpoint populations for…

Machine Learning · Statistics 2026-02-05 Zhongming Xie , Joseph Giorgio , Jingshen Wang

Tree ensemble models like random forests and gradient boosting machines are widely used in machine learning due to their excellent predictive performance. However, a high-performance ensemble consisting of a large number of decision trees…

Machine Learning · Statistics 2024-10-28 Zebin Yang , Agus Sudjianto , Xiaoming Li , Aijun Zhang

Decision trees and randomized forests are widely used in computer vision and machine learning. Standard algorithms for decision tree induction optimize the split functions one node at a time according to some splitting criteria. This greedy…

Machine Learning · Computer Science 2015-11-13 Mohammad Norouzi , Maxwell D. Collins , Matthew Johnson , David J. Fleet , Pushmeet Kohli
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