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Imbalanced regression refers to prediction tasks where the target variable is skewed. This skewness hinders machine learning models, especially neural networks, which concentrate on dense regions and therefore perform poorly on…

Machine Learning · Computer Science 2025-08-11 Shayan Alahyari , Mike Domaratzki

We propose SLIM (Stochastic Learning and Inference in overidentified Models), a scalable stochastic approximation framework for nonlinear GMM. SLIM forms iterative updates from independent mini-batches of moments and their derivatives,…

Econometrics · Economics 2025-11-03 Xiaohong Chen , Min Seong Kim , Sokbae Lee , Myung Hwan Seo , Myunghyun Song

Next-generation RNA sequencing (RNA-seq) technology has been widely used to assess full-length RNA isoform abundance in a high-throughput manner. RNA-seq data offer insight into gene expression levels and transcriptome structures, enabling…

Applications · Statistics 2021-12-01 Wei Vivian Li , Anqi Zhao , Shihua Zhang , Jingyi Jessica Li

Modeling cellular dynamics from single-cell RNA sequencing (scRNA-seq) data is critical for understanding cell development and underlying gene regulatory relationships. Many current methods rely on single-cell velocity to obtain pseudotime,…

Molecular Networks · Quantitative Biology 2024-10-25 Zhen Zhou , Jiachen Li , Hongyi Xin , Xiaoyong Pan , Hong-Bin Shen

This paper is concerned about sparse, continuous frequency estimation in line spectral estimation, and focused on developing gridless sparse methods which overcome grid mismatches and correspond to limiting scenarios of existing grid-based…

Information Theory · Computer Science 2023-07-19 Zai Yang , Lihua Xie

Accelerometer data is commonplace in physical activity research, exercise science, and public health studies, where the goal is to understand and compare physical activity differences between groups and/or subject populations, and to…

Applications · Statistics 2023-06-14 Rui Xie , Lulu Chen , Joon-Hyuk Park , Jeffrey Stout , Ladda Thiamwong

Recent advances in high-resolution sequencing have paved the way for population-scale analysis in single-cell RNA-sequencing (scRNA-seq) data. scRNA-seq data, in particular, have proven to be extremely powerful in profiling a variety of…

Methodology · Statistics 2025-10-30 Hanxuan Ye , Zachary Qian , Hongzhe Li

Spiking Neural Networks (SNNs) have attracted significant attention from researchers across various domains due to their brain-like information processing mechanism. However, SNNs typically grapple with challenges such as extended time…

Neural and Evolutionary Computing · Computer Science 2023-10-24 Yiting Dong , Dongcheng Zhao , Yi Zeng

The Linear Smoothing (LS) scheme \cite{francisa.ortiz-bernardin2017} ameliorates linear and quadratic approximations over convex polytopes by employing a three-point integration scheme. In this work, we propose a linearly consistent one…

Numerical Analysis · Mathematics 2019-04-04 Sundararajan Natarajan , Amrita Francis , Elena Atroshchenko , Stephane PA Bordas

Single-cell RNA sequencing (scRNA-seq) has made significant strides in unraveling the intricate cellular diversity within complex tissues. This is particularly critical in the brain, presenting a greater diversity of cell types than other…

Machine Learning · Computer Science 2023-10-05 Gyutaek Oh , Baekgyu Choi , Inkyung Jung , Jong Chul Ye

In this paper, the method of Singular Spectrum Analysis (SSA) is applied for investigation of the zenith troposphere delay time-series derived from VLBI observations. With the help of this method we can analyze the structure of time-series…

Geophysics · Physics 2009-11-19 Natalia Miller , Zinovy Malkin

Additive spatial statistical models with weakly stationary process assumptions have become standard in spatial statistics. However, one disadvantage of such models is the computation time, which rapidly increases with the number of data…

Methodology · Statistics 2024-10-18 Sudipto Saha , Jonathan R. Bradley

Identifying genetic regulators of DNA methylation (mQTLs) with multivariate models enhances statistical power, but is challenged by missing data from bisulfite sequencing. Standard imputation-based methods can introduce bias, limiting…

Generating turbulent inflow data is a challenging task in zonal Large Eddy Simulation (zLES) and often relies on predefined DNS data to generate synthetic turbulence with the correct statistics. The more accurate, but more involved…

Fluid Dynamics · Physics 2024-04-23 Marcel Blind , Johannes Kleinert , Andrea Beck , Thorsten Lutz

Stochastic approximation (SA) that involves multiple coupled sequences, known as multiple-sequence SA (MSSA), finds diverse applications in the fields of signal processing and machine learning. However, existing theoretical understandings…

Machine Learning · Computer Science 2024-10-18 Yue Huang , Zhaoxian Wu , Shiqian Ma , Qing Ling

Diffusion models have gained attention for their success in modeling complex distributions, achieving impressive perceptual quality in SR tasks. However, existing diffusion-based SR methods often suffer from high computational costs,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Rui Qin , Qijie Wang , Ming Sun , Haowei Zhu , Chao Zhou , Bin Wang

Single-cell RNA sequencing (scRNA-seq) is essential for unraveling cellular heterogeneity and diversity, offering invaluable insights for bioinformatics advancements. Despite its potential, traditional clustering methods in scRNA-seq data…

Machine Learning · Computer Science 2025-10-01 Ping Xu , Zhiyuan Ning , Meng Xiao , Guihai Feng , Xin Li , Yuanchun Zhou , Pengfei Wang

Smoothing of noisy sample covariances is an important component in functional data analysis. We propose a novel covariance smoothing method based on penalized splines and associated software. The proposed method is a bivariate spline…

Methodology · Statistics 2017-04-07 Luo Xiao , Cai Li , William Checkley , Ciprian M. Crainiceanu

Satellite Image Time Series (SITS) is crucial for agricultural semantic segmentation. However, Cloud contamination introduces time gaps in SITS, disrupting temporal dependencies and causing feature shifts, leading to degraded performance of…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Yuze Wang , Mariana Belgiu , Haiyang Wu , Dandan Zhong , Yangyang Cao , Chao Tao

Zero-Shot Learning (ZSL) is achieved via aligning the semantic relationships between the global image feature vector and the corresponding class semantic descriptions. However, using the global features to represent fine-grained images may…

Computer Vision and Pattern Recognition · Computer Science 2018-05-22 Yunlong Yu , Zhong Ji , Yanwei Fu , Jichang Guo , Yanwei Pang , Zhongfei Zhang