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Histopathology image segmentation is essential for delineating tissue structures in skin cancer diagnostics, but modeling spatial context and inter-tissue relationships remains a challenge, especially in regions with overlapping or…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Shravan Venkatraman , Muthu Subash Kavitha , Joe Dhanith P R , V Manikandarajan , Jia Wu

There are multiple scales of abstraction from which we can describe the same image, depending on whether we are focusing on fine-grained details or a more global attribute of the image. In brain mapping, learning to automatically parse…

Nuclear Magnetic Resonance (NMR) spectroscopy is the cornerstone of small-molecule structure elucidation. While deep learning has demonstrated significant potential in automating structure elucidation and spectral simulation, current…

Computational Engineering, Finance, and Science · Computer Science 2026-01-23 Zheng Fang , Chen Yang , Hai-tao Yu , Haoming Luo , Haitao He , Jiaqing Xie , Zhuo Yang , Jun Xia

The throughput of electron microscopes has increased significantly in recent years, enabling detailed analysis of cell morphology and ultrastructure. Analysis of neural circuits at single-synapse resolution remains the flagship target of…

Computer Vision and Pattern Recognition · Computer Science 2019-08-07 Constantin Pape , Alex Matskevych , Adrian Wolny , Julian Hennies , Giula Mizzon , Marion Louveaux , Jacob Musser , Alexis Maizel , Detlev Arendt , Anna Kreshuk

With modern calcium imaging technology, activities of thousands of neurons can be recorded in vivo. These experiments can potentially provide new insights into intrinsic functional neuronal connectivity, defined as contemporaneous…

Methodology · Statistics 2022-08-29 Andersen Chang , Genevera I. Allen

Connectomics - the mapping of neural connections in an organism's brain - currently requires extraordinary human effort to proofread the data collected from imaging and machine-learning assisted segmentation. With the growing excitement…

Neurons and Cognition · Quantitative Biology 2025-11-11 Jeff Brown , Andrew Kirjner , Annika Vivekananthan , Ed Boyden

Recent studies in neuroscience highlight the significant potential of brain connectivity networks, which are commonly constructed from functional magnetic resonance imaging (fMRI) data for brain disorder diagnosis. Traditional brain…

Obtaining high-resolution (HR) segmentations from coarse annotations is a pervasive challenge in computer vision. Applications include inferring pixel-level segmentations from token-level labels in vision transformers, upsampling coarse…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Xiaoling Hu , Peirong Liu , Dina Zemlyanker , Jonathan Williams Ramirez , Oula Puonti , Juan Eugenio Iglesias

Charting the lifespan evolutionary trajectory of brain function serves as the normative standard for preventing mental disorders during brain development and aging. Although numerous MRI studies have mapped the structural connectome for…

Neural and Evolutionary Computing · Computer Science 2025-06-04 Shiang Hu , Xiaolong Huang , Yifan Hu , Xue Xiang , Xiaoliang Sheng , Debin Zhou , Pedro A. Valdes-Sosa

Network science has been applied widely to study brain network organization, especially at the meso-scale, where nodes represent brain areas and edges reflect interareal connectivity inferred from imaging or tract-tracing data. While this…

Neurons and Cognition · Quantitative Biology 2025-08-26 Richard Betzel , Caio Seguin , Maria Grazia Puxeddu

Substantial evidence indicates that major psychiatric disorders are associated with distributed neural dysconnectivity, leading to strong interest in using neuroimaging methods to accurately predict disorder status. In this work, we are…

Machine Learning · Statistics 2014-03-26 Takanori Watanabe , Daniel Kessler , Clayton Scott , Michael Angstadt , Chandra Sripada

Magnetoencephalographic (MEG) recordings from a large normative cohort (n = 619) were processed to extract measures of regional neuroelectric activity. The overall objective of the effort was to use these measures to identify normative…

Neurons and Cognition · Quantitative Biology 2018-11-20 Don Krieger , Paul Shepard , David O. Okonkwo

Based on the data of the NIH-funded Human Connectome Project, we have computed structural connectomes of 426 human subjects in five different resolutions of 83, 129, 234, 463 and 1015 nodes and several edge weights. The graphs are given in…

Neurons and Cognition · Quantitative Biology 2016-10-07 Csaba Kerepesi , Balazs Szalkai , Balint Varga , Vince Grolmusz

The study of random networks in a neuroscientific context has developed extensively over the last couple of decades. By contrast, techniques for the statistical analysis of these networks are less developed. In this paper, we focus on the…

Neurons and Cognition · Quantitative Biology 2017-07-11 Daniel Fraiman , Ricardo Fraiman

Connectomes are spatially embedded networks whose architecture has been shaped by physical constraints and communication needs throughout evolution. Using a decentralized navigation protocol, we investigate the relationship between the…

Neurons and Cognition · Quantitative Biology 2020-02-07 Antoine Allard , M. Ángeles Serrano

Neural networks are increasingly used to support decision-making. To verify their reliability and adaptability, researchers and practitioners have proposed a variety of tools and methods for tasks such as NN code verification, refactoring,…

Machine Learning · Computer Science 2026-02-05 Nadia Daoudi , Jordi Cabot

Volumetric brain reconstructions provide an unprecedented opportunity to gain insights into the complex connectivity patterns of neurons in an increasing number of organisms. Here, we model and quantify the complexity of the resulting…

Neurons and Cognition · Quantitative Biology 2024-05-13 Anastasiya Salova , István A. Kovács

The information content of atomic resolution scanning transmission electron microscopy (STEM) images can often be reduced to a handful of parameters describing each atomic column, chief amongst which is the column position. Neural networks…

Materials Science · Physics 2023-02-22 Jingrui Wei , Ben Blaiszik , Aristana Scourtas , Dane Morgan , Paul M. Voyles

The availability of network datasets advances research in network science, machine learning and related fields by enabling empirical analyses and their reproducibility, algorithm development, model validation and benchmarking. Existing…

The digitization of cultural heritage collections has opened new directions for research, yet the lack of enriched metadata poses a substantial challenge to accessibility, interoperability, and cross-institutional collaboration. In several…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Jan Ignatowicz , Krzysztof Kutt , Grzegorz J. Nalepa
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