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Limited throughput is a key challenge in in-vivo deep-tissue imaging using nonlinear optical microscopy. Point scanning multiphoton microscopy, the current gold standard, is slow especially compared to the wide-field imaging modalities used…

Image and Video Processing · Electrical Eng. & Systems 2022-12-26 Navodini Wijethilake , Mithunjha Anandakumar , Cheng Zheng , Peter T. C. So , Murat Yildirim , Dushan N. Wadduwage

Light propagation in materials with microscopic inhomogeneities is affected by scattering. In scattering materials, such as powders, disordered metamaterials or biological tissue, multiple scattering on sub-wavelength particles makes light…

Disordered Systems and Neural Networks · Physics 2009-11-13 I. M. Vellekoop , A. P. Mosk

Optical scattering presents a major obstacle to high resolution imaging in biological tissue and other turbid media. Conventional photoacoustic imaging can partially overcome this obstacle, enabling imaging of optical absorption in the…

In-camera light scattering is a typical form of non-systematic interference in indirect Time-of-Flight (iToF) cameras, primarily caused by multiple reflections and optical path variations within the camera body. This effect can…

Optics · Physics 2025-11-05 Yansong Du , Jingtong Yao , Yuting Zhou , Feiyu Jiao , Zhaoxiang Jiang , Xun Guan

A fundamental issue that limits the efficiency of many photoelectrochemical systems is that the photon absorption length is typically much longer than the electron diffusion length. Various photon management schemes have been developed to…

Photodetector nonlinearity, the main limiting factor in terms of optical power in the detection chain, is corrected to improve the signal-to-noise ratio of a short-time measurement in dual-comb spectroscopy. An iterative correction…

Instrumentation and Detectors · Physics 2021-09-08 Philippe Guay , Nicolas Bourbeau Hébert , Alex Tourigny-Plante , Vincent Michaud-Belleau , Jérôme Genest

Imaging in thick biological tissues is often degraded by sample-induced aberrations, which reduce image quality and resolution, particularly in super-resolution techniques. While hardware-based adaptive optics, which correct aberrations…

Filtered backprojection (FBP) algorithm is a popular choice for complicated trajectory SAR image formation processing due to its inherent nonlinear motion compensation capability. However, how to efficiently autofocus the defocused FBP…

Signal Processing · Electrical Eng. & Systems 2020-01-08 Xinhua Mao , Lan Ding , Yudong Zhang , Ronghui Zhan , Shan Li

Polarization-sensitive optical coherence tomography (PS-OCT) is a promising biomedical imaging tool for differentiation of various tissue properties. However, the presence of multiple-scattering (MS) signals can degrade the quantitative…

Transparent tissue scaffolds enable illumination of growing tissue to accelerate cell proliferation and improve other cell functions through photobiomodulation. The biphasic dose response of cells exposed to photobiomodulating light…

Biological Physics · Physics 2016-12-12 Jonathan K. George , Hamed Haghshenas , Duncan DHemecourt , Wei Zhu , Lijie Zhang , Volker J. Sorger

The optics of any camera degrades the sharpness of photographs, which is a key visual quality criterion. This degradation is characterized by the point-spread function (PSF), which depends on the wavelengths of light and is variable across…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Thomas Eboli , Jean-Michel Morel , Gabriele Facciolo

Diffuse scattering is a rich source of information about disorder in crystalline materials, which can be modelled using atomistic techniques such as Monte Carlo and molecular dynamics simulations. Modern X-ray and neutron scattering…

Materials Science · Physics 2018-12-21 Joseph A. M. Paddison

Interaction of waves with point and line defects are usually described by $\delta$-function potentials supported on points or lines. In two dimensions, the scattering problem for a finite collection of point defects or parallel line defects…

Quantum Physics · Physics 2022-01-14 Hai V. Bui , Farhang Loran , Ali Mostafazadeh

Depth-from-Focus (DFF) enables precise depth estimation by analyzing focus cues across a stack of images captured at varying focal lengths. While recent learning-based approaches have advanced this field, they often struggle in complex…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Sungmin Woo , Sangyoun Lee

We investigate two-photon quantum interference in an opaque scattering medium that intrinsically supports $10^6$ transmission channels. By adaptive spatial phase-modulation of the incident wavefronts, the photons are directed at targeted…

We report on ultrasonic imaging in a random heterogeneous medium. The goal is to detect flaws embedded deeply into a polycrystalline material. A 64-element array of piezoelectric transmitters/receivers at a central frequency of 5 MHz is…

Other Condensed Matter · Physics 2015-06-19 Sharfine Shahjahan , Alexandre Aubry , Fabienne Rupin , Bertrand Chassignole , Arnaud Derode

Wavefront shaping enables control of classical light through scattering media. Extending these techniques to spatially entangled photons promises new quantum applications, but their fundamental limits, especially when both photons scatter,…

Quantum Physics · Physics 2025-05-06 Ronen Shekel , Sébastien M. Popoff , Yaron Bromberg

Focusing light inside scattering media in a freely addressable fashion is challenging, as the wavefront of the scattered light is highly disordered. Recently developed ultrasound-guided wavefront shaping methods are addressing this…

Optics · Physics 2016-01-20 Haowen Ruan , Mooseok Jang , Changhuei Yang

Temporal focusing two-photon microscopy enables high resolution imaging of fine structures in vivo over a large volume. A limitation of temporal focusing is that signal-to-background ratio and resolution degrade rapidly with increasing…

Multiple scattering is one of the main factors that limits the penetration depth of optical coherence tomography (OCT) in scattering samples. We propose a method termed multi-focus averaging (MFA) to suppress the multiple-scattering signals…

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