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The brain's remarkable and efficient information processing capability is driving research into brain-inspired (neuromorphic) computing paradigms. Artificial aqueous ion channels are emerging as an exciting platform for neuromorphic…

Soft Condensed Matter · Physics 2024-04-26 T. M. Kamsma , J. Kim , K. Kim , W. Q. Boon , C. Spitoni , J. Park , R. van Roij

Experiments have shown that the conductance of conical channels, filled with an aqueous electrolyte, can strongly depend on the history of the applied voltage. These channels hence have a memory and are promising elements in brain-inspired…

Soft Condensed Matter · Physics 2023-06-28 T. M. Kamsma , W. Q. Boon , T. ter Rele , C. Spitoni , R. van Roij

Iontronic neuromorphic computing has emerged as a rapidly expanding paradigm. The arrival of angstrom-confined iontronic devices enables ultra-low power consumption with dynamics and memory timescales that intrinsically align well with…

Soft Condensed Matter · Physics 2026-01-22 T. M. Kamsma , Y. Gu , C. Spitoni , M. Dijkstra , Y. Xie , R. van Roij

Conical channels filled with an aqueous electrolyte have been proposed as promising candidates for iontronic neuromorphic circuits. This is facilitated by a novel analytical model for the internal channel dynamics [Kamsma et al.,…

Biological Physics · Physics 2024-01-31 T. M. Kamsma , W. Q. Boon , C. Spitoni , R. van Roij

We present an integrated iontronic memristor circuit that reproduces biologically inspired Spike Rate-Dependent Plasticity (SRDP) and functions as a physical nonlinear frequency kernel, which we demonstrate can be used to classify natural…

Soft Condensed Matter · Physics 2026-03-23 T. M. Kamsma , Y. Gu , D. Shi , C. Spitoni , M. Dijkstra , R. van Roij , Y. Xie

Conical microfluidic channels filled with electrolytes exhibit volatile memristive behavior, offering a promising platform for energy-efficient, neuromorphic computing. Here, we integrate these iontronic channels as additional nonlinear…

Soft Condensed Matter · Physics 2026-04-08 Nex C. X. Stuhlmüller , René van Roij , Marjolein Dijkstra

Primary vestibular neurons are categorized as either regularly or irregularly firing afferents that use rate and temporal sensory encoding strategies, respectively. While many factors influence firing in these neurons, recent work in…

Neurons and Cognition · Quantitative Biology 2021-08-03 Selina Baeza Loya

Inspired by the brain, we present a physical alternative to traditional digital neural networks -- a microfluidic network in which nodes are connected by conical, electrolyte-filled channels acting as memristive iontronic synapses. Their…

Soft Condensed Matter · Physics 2025-11-07 Monica Conte , René van Roij , Marjolein Dijkstra

Fluidic iontronics offer a unique capability for emulating the chemical processes found in neurons. We extract multiple distinct chemically regulated synaptic features from an experimentally accessible conical microfluidic channel carrying…

Soft Condensed Matter · Physics 2026-02-13 T. M. Kamsma , M. S. Klop , W. Q. Boon , C. Spitoni , B. Rueckauer , R. van Roij

Neuromorphic computing-modelled after the functionality and efficiency of biological neural systems-offers promising new directions for advancing artificial intelligence and computational models. Photonic techniques for neuromorphic…

We propose a spintronics-based hardware implementation of neuromorphic computing, specifically, the spiking neural network, using topological winding textures in one-dimensional antiferromagnets. The consistency of such a network is…

Mesoscale and Nanoscale Physics · Physics 2020-11-18 Shu Zhang , Yaroslav Tserkovnyak

Cortical neurons include many sub-cellular processes, operating at multiple timescales, which may affect their response to stimulation through non-linear and stochastic interaction with ion channels and ionic concentrations. Since new…

Neurons and Cognition · Quantitative Biology 2014-05-01 Daniel Soudry , Ron Meir

Neuronal cells present periodic trains of localized voltage spikes involving a large amount of different ionic channels. A relevant question is whether this is a cooperative effect or it could also be an intrinsic property of individual…

Biological Physics · Physics 2018-04-17 Laureano Ramírez-Piscina , José M. Sancho

We describe a simple conductance-based model neuron that includes intra- and extra-cellular ion concentration dynamics and show that this model exhibits periodic bursting. The bursting arises as the fast spiking behavior of the neuron is…

Cell Behavior · Quantitative Biology 2011-09-22 Ernest Barreto , John R. Cressman

We introduce a methodology to implement the physiological transition {between distinct neuronal spiking modes} in electronic circuits composed of resistors, capacitors and transistors. The result is a simple neuromorphic device organized by…

Optimization and Control · Mathematics 2019-11-14 Fernando Castaños , Alessio Franci

Neuromorphic computing, inspired by the functionality and efficiency of biological neural systems, holds promise for advancing artificial intelligence and computational paradigms. Resonant tunneling diodes (RTDs), thanks to their ability to…

In living organisms, information is processed in interconnected symphonies of ionic currents spiking through protein ion channels. As a result of dynamically switching their conductive states, ion channels exhibit a variety of…

Mesoscale and Nanoscale Physics · Physics 2024-01-15 Yechan Noh , Alex Smolyanitsky

Iontronics combines ions as charge carriers with electronic-like operations, enabling unique information processing, chemical regulation, and enhanced bio-integrability. Standard simulation tools encounter difficulties in effectively…

Emerging Technologies · Computer Science 2024-12-12 Noa Edri Fraiman , Barak Sabbagh , Gilad Yossifon , Alexander Fish

Spiking networks that perform probabilistic inference have been proposed both as models of cortical computation and as candidates for solving problems in machine learning. However, the evidence for spike-based computation being in any way…

Neural and Evolutionary Computing · Computer Science 2017-10-12 Luziwei Leng , Roman Martel , Oliver Breitwieser , Ilja Bytschok , Walter Senn , Johannes Schemmel , Karlheinz Meier , Mihai A. Petrovici

This work proposes a two-dimensional electrophysiological model for describing neuronal responses to external electric stimuli under patch-clamped conditions. Our proposed model successfully captures the key features of the Hodgkin-Huxley…

Neurons and Cognition · Quantitative Biology 2023-12-13 Lízia Maria Gonçalves Branco , Rui Manuel Agostinho Dilão
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