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Large language models (LLMs) are being widely applied across various fields, but as tasks become more complex, evaluating their responses is increasingly challenging. Compared to human evaluators, the use of LLMs to support performance…

Artificial Intelligence · Computer Science 2025-04-25 Yuran Li , Jama Hussein Mohamud , Chongren Sun , Di Wu , Benoit Boulet

An accurate differential diagnosis (DDx) is a cornerstone of medical care, often reached through an iterative process of interpretation that combines clinical history, physical examination, investigations and procedures. Interactive…

Open-source pre-trained Large Language Models (LLMs) exhibit strong language understanding and generation capabilities, making them highly successful in a variety of tasks. However, when used as agents for dealing with complex problems in…

Computation and Language · Computer Science 2024-04-01 Qinhao Zhou , Zihan Zhang , Xiang Xiang , Ke Wang , Yuchuan Wu , Yongbin Li

We develop assistive agents based on Large Language Models (LLMs) that aid interlocutors in business negotiations. Specifically, we simulate business negotiations by letting two LLM-based agents engage in role play. A third LLM acts as a…

Computation and Language · Computer Science 2025-02-18 Yuncheng Hua , Lizhen Qu , Gholamreza Haffari

As Large Language Models (LLMs) have become integral to both research and daily operations, rigorous evaluation is crucial. This assessment is important not only for individual tasks but also for understanding their societal impact and…

Software Engineering · Computer Science 2024-04-02 Zeeshan Rasheed , Muhammad Waseem , Kari Systä , Pekka Abrahamsson

Large Language Models (LLMs) are increasingly explored for legal argument generation, yet they pose significant risks of manipulation through hallucination and ungrounded persuasion, and often fail to utilize provided factual bases…

Artificial Intelligence · Computer Science 2025-10-27 Li Zhang , Kevin D. Ashley

Large Language Models (LLMs) have emerged as powerful candidates to inform clinical decision-making processes. While these models play an increasingly prominent role in shaping the digital landscape, two growing concerns emerge in…

Computation and Language · Computer Science 2024-04-24 Raphael Poulain , Hamed Fayyaz , Rahmatollah Beheshti

Limited access to mental healthcare, extended wait times, and increasing capabilities of Large Language Models (LLMs) has led individuals to turn to LLMs for fulfilling their mental health needs. However, examining the multi-turn mental…

Computation and Language · Computer Science 2025-05-29 Mohit Chandra , Siddharth Sriraman , Harneet Singh Khanuja , Yiqiao Jin , Munmun De Choudhury

Multi-agent large language model (LLM) systems have shown promise for solving complex tasks through agent collaboration. However, existing frameworks assign tasks based on predefined roles without considering whether an agent can accurately…

Artificial Intelligence · Computer Science 2026-05-19 Chenyu Wang , Yang Shu

The introduction of large language models (LLMs) has greatly enhanced the capabilities of software agents. Instead of relying on rule-based interactions, agents can now interact in flexible ways akin to humans. However, this flexibility…

Human-Computer Interaction · Computer Science 2026-02-04 Joar Sabel , Mattias Wingren , Andreas Lundell , Sören Andersson , Sara Rosenberg , Susanne Hägglund , Linda Estman , Malin Andtfolk

Large Language Models (LLMs) have demonstrated impressive performance across diverse domains, yet they still encounter challenges such as insufficient domain-specific knowledge, biases, and hallucinations. This underscores the need for…

Computation and Language · Computer Science 2025-04-07 Hongliu Cao , Ilias Driouich , Robin Singh , Eoin Thomas

Large Language Models (LLMs) have emerged as formidable instruments capable of comprehending and producing human-like text. This paper explores the potential of LLMs, to shape user perspectives and subsequently influence their decisions on…

Artificial Intelligence · Computer Science 2024-09-04 Ganesh Prasath Ramani , Shirish Karande , Santhosh V , Yash Bhatia

Automatic diagnosis is a significant application of AI in healthcare, where diagnoses are generated based on the symptom description of patients. Previous works have approached this task directly by modeling the relationship between the…

Computation and Language · Computer Science 2024-01-30 Haochun Wang , Sendong Zhao , Zewen Qiang , Nuwa Xi , Bing Qin , Ting Liu

Large Language Models (LLMs) show promise in biomedicine but lack true causal understanding, relying instead on correlations. This paper envisions causal LLM agents that integrate multimodal data (text, images, genomics, etc.) and perform…

Artificial Intelligence · Computer Science 2025-05-23 Adib Bazgir , Amir Habibdoust Lafmajani , Yuwen Zhang

Rare disease diagnosis is inherently challenging due to heterogeneous symptoms, limited clinical familiarity, and fragmented evidence across specialties. Recent large language model (LLM)-based agentic systems have shown promise by…

Human-Computer Interaction · Computer Science 2026-03-31 Peng Kuai , Yukun Yang , Shaolun Ruan , Junchi Xu , Yanjie Zhang , Lin Zhang , Min Zhu , Rui Sheng

This research tests the role of Large Language Models (LLMs) as formal second opinion tools in professional decision-making, particularly focusing on complex medical cases where even experienced physicians seek peer consultation. The work…

Cryptography and Security · Computer Science 2024-10-29 David Noever

There is a significant gap between patient needs and available mental health support today. In this paper, we aim to thoroughly examine the potential of using Large Language Models (LLMs) to assist professional psychotherapy. To this end,…

Computation and Language · Computer Science 2025-01-28 Mian Zhang , Xianjun Yang , Xinlu Zhang , Travis Labrum , Jamie C. Chiu , Shaun M. Eack , Fei Fang , William Yang Wang , Zhiyu Zoey Chen

Creating effective dialogue systems for mental health support requires high-quality multi-turn counseling dialogue data, yet collecting real counselor-client conversations presents significant challenges, including privacy concerns, high…

Computation and Language · Computer Science 2026-05-27 Huachuan Qiu , Zhenzhong Lan

LLM-based agents have emerged as transformative tools capable of executing complex tasks through iterative planning and action, achieving significant advancements in understanding and addressing user needs. Yet, their effectiveness remains…

Human-Computer Interaction · Computer Science 2025-08-26 Mithat Can Ozgun , Jiahuan Pei , Koen Hindriks , Lucia Donatelli , Qingzhi Liu , Junxiao Wang

Answering complex medical questions requires not only domain expertise and patient-specific information, but also structured and multi-perspective reasoning. Existing multi-agent approaches often rely on fixed roles or shallow interaction…

Artificial Intelligence · Computer Science 2026-03-04 Siqi Ma , Jiajie Huang , Fan Zhang , Yue Shen , Jinlin Wu , Guohui Fan , Zhu Zhang , Zelin Zang
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