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We consider the problem of estimating the average treatment effect (ATE) when both randomized control trial (RCT) data and external real-world data (RWD) are available. We decompose the ATE estimand as the difference between a pooled-ATE…

Methodology · Statistics 2025-01-22 Mark van der Laan , Sky Qiu , Jens Magelund Tarp , Lars van der Laan

One of the major challenges in estimating conditional potential outcomes and conditional average treatment effects (CATE) is the presence of hidden confounders. Since testing for hidden confounders cannot be accomplished only with…

Machine Learning · Computer Science 2025-06-17 Ahmed Aloui , Juncheng Dong , Ali Hasan , Vahid Tarokh

In this paper we review recent advances in statistical methods for the evaluation of the heterogeneity of treatment effects (HTE), including subgroup identification and estimation of individualized treatment regimens, from randomized…

Methodology · Statistics 2024-10-22 Ilya Lipkovich , David Svensson , Bohdana Ratitch , Alex Dmitrienko

Many experiments in quantum information aim at creating multi-partite entangled states. Quantifying the amount of entanglement that was actually generated can, in principle, be accomplished using full-state tomography. This method requires…

Quantum Physics · Physics 2015-05-13 Harald Wunderlich , Martin B. Plenio

In semi-logarithmic regressions, treatment coefficients are often interpreted as approximations of the average treatment effect (ATE) in percentage points. This paper highlights the overlooked bias of this approximation under treatment…

Econometrics · Economics 2026-02-04 Ying Zeng

Randomized control trials (RCTs) have been the gold standard to evaluate the effectiveness of a program, policy, or treatment on an outcome of interest. However, many RCTs assume that study participants are willing to share their…

Applications · Statistics 2021-12-07 Manjusha Kancharla , Hyunseung Kang

The age of big data has fueled expectations for accelerating learning. The availability of large data sets enables researchers to achieve more powerful statistical analyses and enhances the reliability of conclusions, which can be based on…

Methodology · Statistics 2023-08-22 Ori Becher , Mira Marcus-Kalish , David M. Steinberg

Quantile regression and quantile treatment effect methods are powerful econometric tools for considering economic impacts of events or variables of interest beyond the mean. The use of quantile methods allows for an examination of impacts…

General Economics · Economics 2021-08-16 Damian Clarke , Manuel Llorca Jaña , Daniel Pailañir

We consider the problem of partial identification, the estimation of bounds on the treatment effects from observational data. Although studied using discrete treatment variables or in specific causal graphs (e.g., instrumental variables),…

Machine Learning · Computer Science 2022-10-18 Vahid Balazadeh , Vasilis Syrgkanis , Rahul G. Krishnan

Precision medicine is a rapidly expanding area of health research wherein patient level information is used to inform treatment decisions. A statistical framework helps to formalize the individualization of treatment decisions that…

Methodology · Statistics 2021-12-23 Coraline Danieli , Erica Moodie

In this work, we introduce a new approach for statistical quantification of differential privacy in a black box setting. We present estimators and confidence intervals for the optimal privacy parameter of a randomized algorithm $A$, as well…

Cryptography and Security · Computer Science 2022-05-03 Önder Askin , Tim Kutta , Holger Dette

Randomized controlled trials play an important role in how Internet companies predict the impact of policy decisions and product changes. In these `digital experiments', different units (people, devices, products) respond differently to the…

Applications · Statistics 2015-12-21 Matt Taddy , Matt Gardner , Liyun Chen , David Draper

This paper proposes a new test for the comparison of conditional quantile curves when the outcome of interest, typically a duration, is subject to right censoring. The test can be applied both in the case of two independent samples and for…

Methodology · Statistics 2023-02-08 Lorenzo Tedesco , Ingrid Van Keilegom

The massive deployment of Machine Learning (ML) models raises serious concerns about data protection. Privacy-enhancing technologies (PETs) offer a promising first step, but hard challenges persist in achieving confidentiality and…

Cryptography and Security · Computer Science 2024-07-01 Maurizio Colombo , Rasool Asal , Ernesto Damiani , Lamees Mahmoud AlQassem , Al Anoud Almemari , Yousof Alhammadi

Evidence syntheses and meta-analyses are used to inform clinical practice guidelines and health economic evaluations. However, heterogeneity of treatment effects poses a significant challenge. Conventional meta-analysis addresses…

Nowadays, crowd sensing becomes increasingly more popular due to the ubiquitous usage of mobile devices. However, the quality of such human-generated sensory data varies significantly among different users. To better utilize sensory data,…

Cryptography and Security · Computer Science 2018-10-12 Yaliang Li , Houping Xiao , Zhan Qin , Chenglin Miao , Lu Su , Jing Gao , Kui Ren , Bolin Ding

The heterogeneity of treatment effect (HTE) lies at the heart of precision medicine. Randomized controlled trials are gold-standard for treatment effect estimation but are typically underpowered for heterogeneous effects. In contrast, large…

Methodology · Statistics 2024-11-14 Shu Yang , Siyi Liu , Donglin Zeng , Xiaofei Wang

Treatment effect estimates are often available from randomized controlled trials as a single average treatment effect for a certain patient population. Estimates of the conditional average treatment effect (CATE) are more useful for…

Methodology · Statistics 2023-09-12 Wouter A. C. van Amsterdam , Rajesh Ranganath

Individual Treatment Effect (ITE) estimation is an extensively researched problem, with applications in various domains. We model the case where there exists heterogeneous non-compliance to a randomly assigned treatment, a typical situation…

Machine Learning · Statistics 2020-10-26 Thibaud Rahier , Amélie Héliou , Matthieu Martin , Christophe Renaudin , Eustache Diemert

Treatment effect estimation (TEE) is the task of determining the impact of various treatments on patient outcomes. Current TEE methods fall short due to reliance on limited labeled data and challenges posed by sparse and high-dimensional…

Machine Learning · Computer Science 2024-03-07 Ruoqi Liu , Lingfei Wu , Ping Zhang