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The application of large language models (LLMs) in healthcare holds significant promise for enhancing clinical decision-making, medical research, and patient care. However, their integration into real-world clinical settings raises critical…

Computers and Society · Computer Science 2025-09-18 Manar Aljohani , Jun Hou , Sindhura Kommu , Xuan Wang

Matching patients to clinical trial options is critical for identifying novel treatments, especially in oncology. However, manual matching is labor-intensive and error-prone, leading to recruitment delays. Pipelines incorporating large…

Computation and Language · Computer Science 2025-09-25 Braxton A. Morrison , Madhumita Sushil , Jacob S. Young

Large language models (LLMs) excel on many NLP benchmarks, but their behavior on real-world, semi-structured prediction remains underexplored. We present LlaMADRS, a benchmark for structured clinical assessment from dialogue built on the…

Human-Computer Interaction · Computer Science 2026-04-23 Gaoussou Youssouf Kebe , Jeffrey M. Girard , Einat Liebenthal , Justin Baker , Fernando De la Torre , Louis-Philippe Morency

Large vision language models (LVLMs) have improved the document understanding capabilities remarkably, enabling the handling of complex document elements, longer contexts, and a wider range of tasks. However, existing document understanding…

Artificial Intelligence · Computer Science 2025-07-16 Chao Deng , Jiale Yuan , Pi Bu , Peijie Wang , Zhong-Zhi Li , Jian Xu , Xiao-Hui Li , Yuan Gao , Jun Song , Bo Zheng , Cheng-Lin Liu

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

Large Language Models (LLMs) hold significant promise for transforming digital health by enabling automated medical question answering. However, ensuring these models meet critical industry standards for factual accuracy, usefulness, and…

Computation and Language · Computer Science 2025-10-10 Mohammad Anas Azeez , Rafiq Ali , Ebad Shabbir , Zohaib Hasan Siddiqui , Gautam Siddharth Kashyap , Jiechao Gao , Usman Naseem

Large language models (LLMs) are approaching expert-level performance in medical question answering (QA), demonstrating strong potential to improve public healthcare. However, underlying biases related to sensitive attributes such as sex…

Artificial Intelligence · Computer Science 2026-01-13 Ying Xiao , Jie Huang , Ruijuan He , Jing Xiao , Mohammad Reza Mousavi , Yepang Liu , Kezhi Li , Zhenpeng Chen , Jie M. Zhang

The evaluation of Large Language Models (LLMs) in healthcare has been dominated by physician-centric, English-language benchmarks, creating a dangerous illusion of competence that ignores the interprofessional nature of patient care. To…

Computation and Language · Computer Science 2025-06-30 Andrew Maranhão Ventura D'addario

As large language models (LLMs) develop increasingly sophisticated capabilities and find applications in medical settings, it becomes important to assess their medical safety due to their far-reaching implications for personal and public…

Artificial Intelligence · Computer Science 2024-10-11 Tessa Han , Aounon Kumar , Chirag Agarwal , Himabindu Lakkaraju

Large Language Models (LLMs) have emerged as promising solutions for a variety of medical and clinical decision support applications. However, LLMs are often subject to different types of biases, which can lead to unfair treatment of…

Computation and Language · Computer Science 2024-08-23 Raphael Poulain , Hamed Fayyaz , Rahmatollah Beheshti

Evaluating large language models (LLMs) for medical applications remains challenging due to benchmark saturation, limited data accessibility, and insufficient coverage of relevant tasks. Existing suites have either saturated, heavily depend…

This paper introduces LongBench v2, a benchmark designed to assess the ability of LLMs to handle long-context problems requiring deep understanding and reasoning across real-world multitasks. LongBench v2 consists of 503 challenging…

Computation and Language · Computer Science 2025-01-06 Yushi Bai , Shangqing Tu , Jiajie Zhang , Hao Peng , Xiaozhi Wang , Xin Lv , Shulin Cao , Jiazheng Xu , Lei Hou , Yuxiao Dong , Jie Tang , Juanzi Li

HealthBranches is a novel benchmark dataset for medical Question-Answering (Q&A), specifically designed to evaluate complex reasoning in Large Language Models (LLMs). This dataset is generated through a semi-automated pipeline that…

Computation and Language · Computer Science 2025-08-12 Cristian Cosentino , Annamaria Defilippo , Marco Dossena , Christopher Irwin , Sara Joubbi , Pietro Liò

Clinical trial matching is a key process in health delivery and discovery. In practice, it is plagued by overwhelming unstructured data and unscalable manual processing. In this paper, we conduct a systematic study on scaling clinical trial…

Recent advancements in large language models (LLMs) have transformed the field of question answering (QA). However, evaluating LLMs in the medical field is challenging due to the lack of standardized and comprehensive datasets. To address…

Computation and Language · Computer Science 2023-10-24 Junling Liu , Peilin Zhou , Yining Hua , Dading Chong , Zhongyu Tian , Andrew Liu , Helin Wang , Chenyu You , Zhenhua Guo , Lei Zhu , Michael Lingzhi Li

With the rapid development of artificial intelligence, large language models (LLMs) have shown promising capabilities in mimicking human-level language comprehension and reasoning. This has sparked significant interest in applying LLMs to…

Computation and Language · Computer Science 2023-11-06 Mingze Yuan , Peng Bao , Jiajia Yuan , Yunhao Shen , Zifan Chen , Yi Xie , Jie Zhao , Yang Chen , Li Zhang , Lin Shen , Bin Dong

Large Language Models (LLMs) have become a key topic in AI and NLP, transforming sectors like healthcare, finance, education, and marketing by improving customer service, automating tasks, providing insights, improving diagnostics, and…

Artificial Intelligence · Computer Science 2025-12-05 Vignesh Kumar Kembu , Pierandrea Morandini , Marta Bianca Maria Ranzini , Antonino Nocera

Automatic disease diagnosis has become increasingly valuable in clinical practice. The advent of large language models (LLMs) has catalyzed a paradigm shift in artificial intelligence, with growing evidence supporting the efficacy of LLMs…

Background: Advances in artificial intelligence, particularly large language models (LLMs), have the potential to enhance technical expertise in magnetic resonance imaging (MRI), regardless of operator skill or geographic location. Methods:…

Medical Physics · Physics 2024-11-20 Alan B McMillan

Medical question answering (QA) benchmarks often focus on multiple-choice or fact-based tasks, leaving open-ended answers to real patient questions underexplored. This gap is particularly critical in mental health, where patient questions…

Computation and Language · Computer Science 2026-05-15 Yahan Li , Jifan Yao , John Bosco S. Bunyi , Adam C. Frank , Angel Hsing-Chi Hwang , Ruishan Liu